"Receptors, Dopamine D2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its effects. D2-class receptor genes contain INTRONS, and the receptors inhibit ADENYLYL CYCLASES.
| Descriptor ID |
D017448
|
| MeSH Number(s) |
D12.776.543.750.670.300.400.500 D12.776.543.750.695.150.400.500 D12.776.543.750.720.330.400.500
|
| Concept/Terms |
Receptors, Dopamine D2- Receptors, Dopamine D2
- Dopamine-D2 Receptor
- Dopamine D2 Receptor
- Receptor, Dopamine-D2
- Dopamine D2 Receptors
- D2 Receptors, Dopamine
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Dopamine D2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Dopamine [D12.776.543.750.670.300.400]
- Receptors, Dopamine D2 [D12.776.543.750.670.300.400.500]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Dopamine [D12.776.543.750.695.150.400]
- Receptors, Dopamine D2 [D12.776.543.750.695.150.400.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Dopamine [D12.776.543.750.720.330.400]
- Receptors, Dopamine D2 [D12.776.543.750.720.330.400.500]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Dopamine D2".
This graph shows the total number of publications written about "Receptors, Dopamine D2" by people in this website by year, and whether "Receptors, Dopamine D2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 2 | 0 | 2 |
| 2000 | 0 | 2 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 2 | 0 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 3 | 0 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 3 | 3 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Dopamine D2" by people in Profiles.
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Serotonin neurons integrate GABA and dopamine inputs to regulate meal initiation. Metabolism. 2025 Feb; 163:156099.
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PharmacoSTORM nanoscale pharmacology reveals cariprazine binding on Islands of Calleja granule cells. Nat Commun. 2021 11 11; 12(1):6505.
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Brain network dynamics during working memory are modulated by dopamine and diminished in schizophrenia. Nat Commun. 2021 06 09; 12(1):3478.
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Cholinergic neurons constitutively engage the ISR for dopamine modulation and skill learning in mice. Science. 2021 04 23; 372(6540).
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PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia. Nat Commun. 2020 11 19; 11(1):5903.
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Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors. J Biol Chem. 2019 12 13; 294(50):19279-19291.
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REST-DRD2 mechanism impacts glioblastoma stem cell-mediated tumorigenesis. Neuro Oncol. 2019 06 10; 21(6):775-785.
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Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration. J Immunother Cancer. 2019 05 22; 7(1):136.
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Investigational dopamine antagonists for the treatment of schizophrenia. Expert Opin Investig Drugs. 2017 Jun; 26(6):687-698.
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Intramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariation. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):3539-44.