"Tubercidin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.
| Descriptor ID |
D014372
|
| MeSH Number(s) |
D03.633.100.759.590.910 D13.570.583.910 D13.570.800.850
|
| Concept/Terms |
Tubercidin- Tubercidin
- 4-Amino-7 beta-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine
- 7-Deazaadenosine
- 7 Deazaadenosine
- Deazaadenosine
|
Below are MeSH descriptors whose meaning is more general than "Tubercidin".
Below are MeSH descriptors whose meaning is more specific than "Tubercidin".
This graph shows the total number of publications written about "Tubercidin" by people in this website by year, and whether "Tubercidin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tubercidin" by people in Profiles.
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2-Aryl-8-aza-3-deazaadenosine analogues of 5'-O-[N-(salicyl)sulfamoyl]adenosine: Nucleoside antibiotics that block siderophore biosynthesis in Mycobacterium tuberculosis. Bioorg Med Chem. 2016 07 15; 24(14):3133-43.
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Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA. 2006 May; 12(5):797-806.
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Renal organic cation and nucleoside transport. Biochem Pharmacol. 2002 Jul 15; 64(2):185-90.
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Role of organic cation transporters in the renal secretion of nucleosides. Biochem Pharmacol. 2000 Jul 15; 60(2):215-9.
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A nucleoside-sensitive organic cation transporter in opossum kidney cells. Am J Physiol. 1999 02; 276(2):F323-8.
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A pre-transition-state mimic of an enzyme: X-ray structure of adenosine deaminase with bound 1-deazaadenosine and zinc-activated water. Biochemistry. 1993 Feb 23; 32(7):1689-94.
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Selective protection of tubercidin toxicity by nitrobenzyl thioinosine in normal tissues but not in human neuroblastoma cells. Cancer Chemother Pharmacol. 1986; 17(3):264-8.