"Inosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It is an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage. It also occurs in the anticodon of certain transfer RNA molecules. (Dorland, 28th ed)
| Descriptor ID |
D007288
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| MeSH Number(s) |
D03.633.100.759.590.616 D13.570.583.616 D13.570.800.573
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Inosine".
Below are MeSH descriptors whose meaning is more specific than "Inosine".
This graph shows the total number of publications written about "Inosine" by people in this website by year, and whether "Inosine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Inosine" by people in Profiles.
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Selective refueling of CAR T?cells using ADA1 and CD26 boosts antitumor immunity. Cell Rep Med. 2024 May 21; 5(5):101530.
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The Enzymatic Activity of Inosine 5'-Monophosphate Dehydrogenase May Not Be a Vulnerable Target for Staphylococcus aureus Infections. ACS Infect Dis. 2021 11 12; 7(11):3062-3076.
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Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy. Science. 2020 09 18; 369(6510):1481-1489.
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Regulation of RNA editing by RNA-binding proteins in human cells. Commun Biol. 2019; 2:19.
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Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial. JAMA Neurol. 2014 Feb; 71(2):141-50.
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Altered A-to-I RNA editing in human embryogenesis. PLoS One. 2012; 7(7):e41576.
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Consistent levels of A-to-I RNA editing across individuals in coding sequences and non-conserved Alu repeats. BMC Genomics. 2010 Oct 28; 11:608.
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Alu sequences in undifferentiated human embryonic stem cells display high levels of A-to-I RNA editing. PLoS One. 2010 Jun 21; 5(6):e11173.
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Widespread cleavage of A-to-I hyperediting substrates. RNA. 2009 Sep; 15(9):1632-9.
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Altered adenosine-to-inosine RNA editing in human cancer. Genome Res. 2007 Nov; 17(11):1586-95.