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MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition.
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MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition.
MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition. Oncogene. 2012 Oct 11; 31(41):4434-46.
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PubMed
subject areas
Antibodies, Monoclonal, Humanized
Antineoplastic Agents
Apoptosis
Base Sequence
Breast Neoplasms
Cell Line, Tumor
Chromatin Immunoprecipitation
Drug Resistance, Neoplasm
Female
Gene Expression Regulation, Neoplastic
Gene Knockdown Techniques
Humans
Intracellular Signaling Peptides and Proteins
Phosphorylation
Protein Array Analysis
Protein Processing, Post-Translational
Pteridines
Ribosomal Protein S6 Kinases, 90-kDa
Sequence Analysis, DNA
Transcription, Genetic
Trastuzumab
Y-Box-Binding Protein 1
authors with profiles
GORDON B MILLS