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Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML.
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Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML.
Simultaneous activation of p53 and inhibition of XIAP enhance the activation of apoptosis signaling pathways in AML. Blood. 2010 Jan 14; 115(2):306-14.
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PubMed
subject areas
Animals
Apoptosis
Apoptosis Regulatory Proteins
Blast Crisis
Carrier Proteins
Caspase 6
Cell Line, Tumor
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Leukemic
Gene Knockdown Techniques
Humans
Imidazoles
Intracellular Signaling Peptides and Proteins
Leukemia, Myeloid, Acute
Mice
Mitochondrial Proteins
Piperazines
Proto-Oncogene Proteins c-mdm2
Signal Transduction
Stromal Cells
Tumor Suppressor Protein p53
X-Linked Inhibitor of Apoptosis Protein
authors with profiles
MICHAEL ANDREEFF
BING Z CARTER