JASON KARCH

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular Physiology & Biophysics
AddressOne Baylor Plaza
Houston, TX 77030
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Verify Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Patel P, Karch J. Regulation of cell death in the cardiovascular system. Int Rev Cell Mol Biol. 2020; 353:153-209. PMID: 32381175.
      Citations:    Fields:    
    2. Karch J, Bround MJ, Khalil H, Sargent MA, Latchman N, Terada N, Peixoto PM, Molkentin JD. Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD. Sci Adv. 2019 08; 5(8):eaaw4597. PMID: 31489369.
      Citations: 17     Fields:    Translation:AnimalsCells
    3. Schips TG, Vanhoutte D, Vo A, Correll RN, Brody MJ, Khalil H, Karch J, Tjondrokoesoemo A, Sargent MA, Maillet M, Ross RS, Molkentin JD. Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. Nat Commun. 2019 01 08; 10(1):76. PMID: 30622267.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    4. Maliken BD, Kanisicak O, Karch J, Khalil H, Fu X, Boyer JG, Prasad V, Zheng Y, Molkentin JD. Gata4-Dependent Differentiation of c-Kit+-Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart. Circulation. 2018 09 04; 138(10):1012-1024. PMID: 29666070.
      Citations: 12     Fields:    Translation:AnimalsCells
    5. van Berlo JH, Kanisicak O, Maillet M, Vagnozzi RJ, Karch J, Lin SJ, Middleton RC, Marbán E, Molkentin JD. van Berlo et al. reply. Nature. 2018 03 21; 555(7697):E18. PMID: 29565361.
      Citations: 2     Fields:    
    6. Karch J, Schips TG, Maliken BD, Brody MJ, Sargent MA, Kanisicak O, Molkentin JD. Autophagic cell death is dependent on lysosomal membrane permeability through Bax and Bak. Elife. 2017 11 17; 6. PMID: 29148970.
      Citations: 11     Fields:    Translation:AnimalsCells
    7. Khalil H, Kanisicak O, Prasad V, Correll RN, Fu X, Schips T, Vagnozzi RJ, Liu R, Huynh T, Lee SJ, Karch J, Molkentin JD. Fibroblast-specific TGF-ß-Smad2/3 signaling underlies cardiac fibrosis. J Clin Invest. 2017 Oct 02; 127(10):3770-3783. PMID: 28891814.
      Citations: 73     Fields:    Translation:AnimalsCells
    8. Kanisicak O, Khalil H, Ivey MJ, Karch J, Maliken BD, Correll RN, Brody MJ, J Lin SC, Aronow BJ, Tallquist MD, Molkentin JD. Genetic lineage tracing defines myofibroblast origin and function in the injured heart. Nat Commun. 2016 07 22; 7:12260. PMID: 27447449.
      Citations: 139     Fields:    Translation:AnimalsCells
    9. Brody MJ, Schips TG, Vanhoutte D, Kanisicak O, Karch J, Maliken BD, Blair NS, Sargent MA, Prasad V, Molkentin JD. Dissection of Thrombospondin-4 Domains Involved in Intracellular Adaptive Endoplasmic Reticulum Stress-Responsive Signaling. Mol Cell Biol. 2016 Jan 01; 36(1):2-12. PMID: 26459760.
      Citations: 11     Fields:    Translation:AnimalsCells
    10. Karch J, Kanisicak O, Brody MJ, Sargent MA, Michael DM, Molkentin JD. Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death. PLoS One. 2015; 10(6):e0130520. PMID: 26061004.
      Citations: 22     Fields:    Translation:AnimalsCells
    11. Karch J, Molkentin JD. Regulated necrotic cell death: the passive aggressive side of Bax and Bak. Circ Res. 2015 May 22; 116(11):1800-9. PMID: 25999420.
      Citations: 32     Fields:    Translation:HumansCells
    12. Karch J, Molkentin JD. Identifying the components of the elusive mitochondrial permeability transition pore. Proc Natl Acad Sci U S A. 2014 Jul 22; 111(29):10396-7. PMID: 25002521.
      Citations: 26     Fields:    Translation:HumansAnimals
    13. Wissing ER, Boyer JG, Kwong JQ, Sargent MA, Karch J, McNally EM, Otsu K, Molkentin JD. P38a MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism. Hum Mol Genet. 2014 Oct 15; 23(20):5452-63. PMID: 24876160.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    14. van Berlo JH, Kanisicak O, Maillet M, Vagnozzi RJ, Karch J, Lin SC, Middleton RC, Marbán E, Molkentin JD. c-kit+ cells minimally contribute cardiomyocytes to the heart. Nature. 2014 May 15; 509(7500):337-41. PMID: 24805242.
      Citations: 274     Fields:    Translation:AnimalsCells
    15. Karch J, Kwong JQ, Burr AR, Sargent MA, Elrod JW, Peixoto PM, Martinez-Caballero S, Osinska H, Cheng EH, Robbins J, Kinnally KW, Molkentin JD. Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice. Elife. 2013 Aug 27; 2:e00772. PMID: 23991283.
      Citations: 79     Fields:    Translation:Animals
    16. Karch J, Molkentin JD. Is p53 the long-sought molecular trigger for cyclophilin D-regulated mitochondrial permeability transition pore formation and necrosis? Circ Res. 2012 Oct 26; 111(10):1258-60. PMID: 23104876.
      Citations: 18     Fields:    
    17. Comstock CE, Augello MA, Schiewer MJ, Karch J, Burd CJ, Ertel A, Knudsen ES, Jessen WJ, Aronow BJ, Knudsen KE. Cyclin D1 is a selective modifier of androgen-dependent signaling and androgen receptor function. J Biol Chem. 2011 Mar 11; 286(10):8117-27. PMID: 21212260.
      Citations: 17     Fields:    Translation:HumansCells
    18. Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD. Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice. J Clin Invest. 2010 Oct; 120(10):3680-7. PMID: 20890047.
      Citations: 135     Fields:    Translation:AnimalsCells
    19. Comstock CE, Augello MA, Benito RP, Karch J, Tran TH, Utama FE, Tindall EA, Wang Y, Burd CJ, Groh EM, Hoang HN, Giles GG, Severi G, Hayes VM, Henderson BE, Le Marchand L, Kolonel LN, Haiman CA, Baffa R, Gomella LG, Knudsen ES, Rui H, Henshall SM, Sutherland RL, Knudsen KE. Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer. Clin Cancer Res. 2009 Sep 01; 15(17):5338-49. PMID: 19706803.
      Citations: 43     Fields:    Translation:HumansCells
    KARCH's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (116)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _