Endothelin Receptor Antagonists

"Endothelin Receptor Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Compounds and drugs that bind to and inhibit or block the activation of ENDOTHELIN RECECPTORS.

Descriptor ID	D065128
MeSH Number(s)	D27.505.519.364
Concept/Terms	Endothelin Receptor Antagonists Endothelin Receptor Antagonists Antagonists, Endothelin Receptor Endothelin Antagonists Antagonists, Endothelin

Below are MeSH descriptors whose meaning is more general than "Endothelin Receptor Antagonists".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Endothelin Receptor Antagonists [D27.505.519.364]

Below are MeSH descriptors whose meaning is more specific than "Endothelin Receptor Antagonists".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Endothelin Receptor Antagonists" by people in this website by year, and whether "Endothelin Receptor Antagonists" was a major or minor topic of these publications.

Bar chart showing 21 publications over 12 distinct years, with a maximum of 4 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2001	2	1	3
2002	1	1	2
2003	0	1	1
2004	1	0	1
2007	1	0	1
2008	1	0	1
2009	0	1	1
2010	1	1	2
2011	2	1	3
2015	4	0	4
2017	1	0	1

Below are the most recent publications written about "Endothelin Receptor Antagonists" by people in Profiles.

Smith MP, Rowling EJ, Miskolczi Z, Ferguson J, Spoerri L, Haass NK, Sloss O, McEntegart S, Arozarena I, von Kriegsheim A, Rodriguez J, Brunton H, Kmarashev J, Levesque MP, Dummer R, Frederick DT, Andrews MC, Cooper ZA, Flaherty KT, Wargo JA, Wellbrock C. Targeting endothelin receptor signalling overcomes heterogeneity driven therapy failure. EMBO Mol Med. 2017 08; 9(8):1011-1029.

View in: PubMed
Snarr BS, Paridon SM, Rychik J, Goldberg DJ. Pulmonary vasodilator therapy in the failing Fontan circulation: rationale and efficacy. Cardiol Young. 2015 Dec; 25(8):1489-92.

View in: PubMed
Bednov A, Espinoza J, Betancourt A, Vedernikov Y, Belfort M, Yallampalli C. L-arginine prevents hypoxia-induced vasoconstriction in dual-perfused human placental cotyledons. Placenta. 2015 Nov; 36(11):1254-9.

View in: PubMed
Carducci MA, Manola J, Nair SG, Liu G, Rousey S, Dutcher JP, Wilding G. Atrasentan in Patients With Advanced Renal Cell Carcinoma: A Phase 2 Trial of the ECOG-ACRIN Cancer Research Group (E6800). Clin Genitourin Cancer. 2015 Dec; 13(6):531-539.e1.

View in: PubMed
Kim SJ, Lee HJ, Kim MS, Choi HJ, He J, Wu Q, Aldape K, Weinberg JS, Yung WK, Conrad CA, Langley RR, Lehembre F, Regenass U, Fidler IJ. Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice. Clin Cancer Res. 2015 Oct 15; 21(20):4630-41.

View in: PubMed
Franklin WJ, Parekh DR, Safdar Z. Adult congenital heart disease and pulmonary arterial hypertension: the Texas Adult Congenital Heart Program experience. Postgrad Med. 2011 Nov; 123(6):32-45.

View in: PubMed
Tam Tam KB, George E, Cockrell K, Arany M, Speed J, Martin JN, Lamarca B, Granger JP. Endothelin type A receptor antagonist attenuates placental ischemia-induced hypertension and uterine vascular resistance. Am J Obstet Gynecol. 2011 Apr; 204(4):330.e1-4.

View in: PubMed
Kim SJ, Kim JS, Kim SW, Brantley E, Yun SJ, He J, Maya M, Zhang F, Wu Q, Lehembre F, Regenass U, Fidler IJ. Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer. Neoplasia. 2011 Feb; 13(2):167-79.

View in: PubMed
Li N, Jia N, Dai DZ, Hu C, Dai Y. Role of endothelin in the effects of isoprenaline on potassium currents and calsequestrin 2 expression in the heart. Clin Exp Pharmacol Physiol. 2010 May; 37(5-6):557-63.

View in: PubMed
Adatia I, Shekerdemian L. The role of calcium channel blockers, steroids, anticoagulation, antiplatelet drugs, and endothelin receptor antagonists. Pediatr Crit Care Med. 2010 Mar; 11(2 Suppl):S46-52.

View in: PubMed

People

Explore

Similar Concepts

Top Journals