Endothelin B Receptor Antagonists
"Endothelin B Receptor Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds and drugs that bind to and inhibit or block the activation of ENDOTHELIN B RECEPTORS.
Descriptor ID |
D065131
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MeSH Number(s) |
D27.505.519.364.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Endothelin B Receptor Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Endothelin B Receptor Antagonists".
This graph shows the total number of publications written about "Endothelin B Receptor Antagonists" by people in this website by year, and whether "Endothelin B Receptor Antagonists" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 3 | 0 | 3 |
2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endothelin B Receptor Antagonists" by people in Profiles.
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Safety, efficacy, and clinical utility of macitentan in the treatment of pulmonary arterial hypertension. Drug Des Devel Ther. 2016; 10:1675-82.
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CPU0213, a non-selective ETA/ETB receptor antagonist, improves pulmonary arteriolar remodeling of monocrotaline-induced pulmonary hypertension in rats. Clin Exp Pharmacol Physiol. 2009 Feb; 36(2):169-75.
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The endothelin receptor antagonist CPU0213 is more effective than aminoguanidine to attenuate isoproterenol-induced vascular abnormality by suppressing overexpression of NADPH oxidase [correction of oxidas], ETA, ETB, and MMP9 in the vasculature. J Cardiovasc Pharmacol. 2008 Jul; 52(1):42-8.
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Endothelin receptor antagonists improve exercise tolerance and oxygen saturations in patients with Eisenmenger syndrome and congenital heart defects. Tex Heart Inst J. 2008; 35(3):256-61.