MEF2 Transcription Factors
"MEF2 Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Activating transcription factors of the MADS family which bind a specific sequence element (MEF2 element) in many muscle-specific genes and are involved in skeletal and cardiac myogenesis, neuronal differentiation and survival/apoptosis.
| Descriptor ID |
D064326
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| MeSH Number(s) |
D12.776.210.500.570.294 D12.776.260.103.750.294 D12.776.260.400.249.624 D12.776.930.125.750.294 D12.776.930.397.700
|
| Concept/Terms |
MEF2 Transcription Factors- MEF2 Transcription Factors
- Transcription Factors, MEF2
- Muscle Enhancer Factor-2
- Enhancer Factor-2, Muscle
- Muscle Enhancer Factor 2
- Myocyte-Specific Enhancer-Binding Factor 2
- Myocyte Specific Enhancer Binding Factor 2
- Myocyte Enhancer Factor 2
- Myocyte-Specific Enhancer Factor 2
- Myocyte Specific Enhancer Factor 2
- MEF2 Proteins
- Muscle-Specific Enhancer Factor-2
- Enhancer Factor-2, Muscle-Specific
- Muscle Specific Enhancer Factor 2
MEF2B Transcription Factor- MEF2B Transcription Factor
- Transcription Factor, MEF2B
- Serum Response Factor-Like Protein 2
- Serum Response Factor Like Protein 2
- Myocyte-Specific Enhancer Factor 2B
- Myocyte Specific Enhancer Factor 2B
- Muscle Enhancer Factor-2B
- Enhancer Factor-2B, Muscle
- Muscle Enhancer Factor 2B
- Muscle-Specific Enhancer Factor-2B
- Enhancer Factor-2B, Muscle-Specific
- Muscle Specific Enhancer Factor 2B
- Myocyte Enhancer Factor 2B
- Myocyte-Specific Enhancer-Binding Factor 2B
- Myocyte Specific Enhancer Binding Factor 2B
- MEF2B Protein
MEF2D Transcription Factor- MEF2D Transcription Factor
- Transcription Factor, MEF2D
- Muscle Enhancer Factor-2D
- Enhancer Factor-2D, Muscle
- Muscle Enhancer Factor 2D
- Muscle-Specific Enhancer Factor-2D
- Enhancer Factor-2D, Muscle-Specific
- Muscle Specific Enhancer Factor 2D
- Myocyte-Specific Enhancer Factor 2D
- Myocyte Specific Enhancer Factor 2D
- Myocyte-Specific Enhancer-Binding Factor 2D
- Myocyte Specific Enhancer Binding Factor 2D
- MEF2D Protein
- Myocyte Enhancer Factor 2D
MEF2A Transcription Factor- MEF2A Transcription Factor
- Transcription Factor, MEF2A
- Muscle Enhancer Factor-2A
- Enhancer Factor-2A, Muscle
- Muscle Enhancer Factor 2A
- Serum Response Factor-Like Protein 1
- Serum Response Factor Like Protein 1
- Myocyte Enhancer Factor 2A
- Myocyte-Specific Enhancer Factor 2A
- Myocyte Specific Enhancer Factor 2A
- Myocyte-Specific Enhancer-Binding Factor 2A
- Myocyte Specific Enhancer Binding Factor 2A
- MEF2A Protein
- Muscle-Specific Enhancer Factor-2A
- Enhancer Factor-2A, Muscle-Specific
- Muscle Specific Enhancer Factor 2A
MEF2C Transcription Factor- MEF2C Transcription Factor
- Transcription Factor, MEF2C
- Muscle Enhancer Factor-2C
- Enhancer Factor-2C, Muscle
- Muscle Enhancer Factor 2C
- Myocyte-Specific Enhancer-Binding Factor 2C
- Myocyte Specific Enhancer Binding Factor 2C
- Myocyte Enhancer Factor 2C
- Myocyte-Specific Enhancer Factor 2C
- Myocyte Specific Enhancer Factor 2C
- MEF2C Protein
- Muscle-Specific Enhancer Factor-2C
- Enhancer Factor-2C, Muscle-Specific
- Muscle Specific Enhancer Factor 2C
|
Below are MeSH descriptors whose meaning is more general than "MEF2 Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "MEF2 Transcription Factors".
This graph shows the total number of publications written about "MEF2 Transcription Factors" by people in this website by year, and whether "MEF2 Transcription Factors" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 2 | 1 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 5 | 6 |
| 2017 | 0 | 1 | 1 |
| 2019 | 2 | 0 | 2 |
| 2024 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "MEF2 Transcription Factors" by people in Profiles.
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Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming. Cell Stem Cell. 2019 07 03; 25(1):87-102.e9.
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Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming. Circulation. 2017 Mar 07; 135(10):978-995.
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Rbfox2-coordinated alternative splicing of Mef2d and Rock2 controls myoblast fusion during myogenesis. Mol Cell. 2014 Aug 21; 55(4):592-603.
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"Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors. J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1656-1664.e2.
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In vivo cardiac cellular reprogramming efficacy is enhanced by angiogenic preconditioning of the infarcted myocardium with vascular endothelial growth factor. J Am Heart Assoc. 2012 Dec; 1(6):e005652.
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Brain-derived neurotrophic factor stimulates the transcriptional and neuroprotective activity of myocyte-enhancer factor 2C through an ERK1/2-RSK2 signaling cascade. J Neurochem. 2007 Aug; 102(3):957-66.
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ZEB1 and c-Jun levels contribute to the establishment of highly lytic Epstein-Barr virus infection in gastric AGS cells. J Virol. 2007 Sep; 81(18):10113-22.
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Overexpression of CUG triplet repeat-binding protein, CUGBP1, in mice inhibits myogenesis. J Biol Chem. 2004 Mar 26; 279(13):13129-39.
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ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons. Proc Natl Acad Sci U S A. 2003 Jul 08; 100(14):8532-7.
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Polymorphic trinucleotide repeat in the MEF2A gene at 15q26 is not expanded in familial cardiomyopathies. Mol Cell Probes. 1997 Feb; 11(1):55-8.