"Inflammasomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.
| Descriptor ID |
D058847
|
| MeSH Number(s) |
D05.500.224
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Inflammasomes".
Below are MeSH descriptors whose meaning is more specific than "Inflammasomes".
This graph shows the total number of publications written about "Inflammasomes" by people in this website by year, and whether "Inflammasomes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 3 | 1 | 4 |
| 2013 | 1 | 2 | 3 |
| 2014 | 7 | 1 | 8 |
| 2015 | 2 | 4 | 6 |
| 2016 | 7 | 5 | 12 |
| 2017 | 9 | 2 | 11 |
| 2018 | 4 | 4 | 8 |
| 2019 | 5 | 1 | 6 |
| 2020 | 1 | 2 | 3 |
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click here.
Below are the most recent publications written about "Inflammasomes" by people in Profiles.
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Hou J, Zhao R, Xia W, Chang CW, You Y, Hsu JM, Nie L, Chen Y, Wang YC, Liu C, Wang WJ, Wu Y, Ke B, Hsu JL, Huang K, Ye Z, Yang Y, Xia X, Li Y, Li CW, Shao B, Tainer JA, Hung MC. PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis. Nat Cell Biol. 2020 10; 22(10):1264-1275.
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Chen H, Tran D, Yang HC, Nylander S, Birnbaum Y, Ye Y. Dapagliflozin and Ticagrelor Have Additive Effects on the Attenuation of the Activation of the NLRP3 Inflammasome and the Progression of Diabetic Cardiomyopathy: an AMPK-mTOR Interplay. Cardiovasc Drugs Ther. 2020 08; 34(4):443-461.
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Karmakar M, Minns M, Greenberg EN, Diaz-Aponte J, Pestonjamasp K, Johnson JL, Rathkey JK, Abbott DW, Wang K, Shao F, Catz SD, Dubyak GR, Pearlman E. N-GSDMD trafficking to neutrophil organelles facilitates IL-1ß release independently of plasma membrane pores and pyroptosis. Nat Commun. 2020 05 05; 11(1):2212.
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Singh GB, Kshirasagar N, Patibandla S, Puchchakayala G, Koka S, Boini KM. Nicotine instigates podocyte injury via NLRP3 inflammasomes activation. Aging (Albany NY). 2019 12 13; 11(24):12810-12821.
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Birnbaum Y, Tran D, Bajaj M, Ye Y. DPP-4 inhibition by linagliptin prevents cardiac dysfunction and inflammation by targeting the Nlrp3/ASC inflammasome. Basic Res Cardiol. 2019 08 06; 114(5):35.
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Shao BZ, Wang SL, Pan P, Yao J, Wu K, Li ZS, Bai Y, Linghu EQ. Targeting NLRP3 Inflammasome in Inflammatory Bowel Disease: Putting out the Fire of Inflammation. Inflammation. 2019 Aug; 42(4):1147-1159.
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Shen YH, Abe JI. Enigma of Inflammasome Activation by Kinases. Arterioscler Thromb Vasc Biol. 2019 08; 39(8):1501-1503.
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Bolívar BE, Vogel TP, Bouchier-Hayes L. Inflammatory caspase regulation: maintaining balance between inflammation and cell death in health and disease. FEBS J. 2019 07; 286(14):2628-2644.
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Koka S, Xia M, Zhang C, Zhang Y, Li PL, Boini KM. Podocyte NLRP3 Inflammasome Activation and Formation by Adipokine Visfatin. Cell Physiol Biochem. 2019; 53(2):355-365.
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Clemens MG. What's New in Shock, December 2018? Shock. 2018 12; 50(6):613-615.