"Inflammasomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multiprotein complexes that mediate the activation of CASPASE-1. Dysregulation of inflammasomes has also been linked to a number of autoinflammatory and autoimmune disorders.
| Descriptor ID |
D058847
|
| MeSH Number(s) |
D05.500.224
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Inflammasomes".
Below are MeSH descriptors whose meaning is more specific than "Inflammasomes".
This graph shows the total number of publications written about "Inflammasomes" by people in this website by year, and whether "Inflammasomes" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 3 | 1 | 4 |
| 2013 | 2 | 0 | 2 |
| 2014 | 7 | 1 | 8 |
| 2015 | 2 | 3 | 5 |
| 2016 | 5 | 1 | 6 |
| 2017 | 9 | 2 | 11 |
| 2018 | 4 | 2 | 6 |
| 2019 | 4 | 1 | 5 |
| 2020 | 9 | 0 | 9 |
| 2021 | 7 | 6 | 13 |
| 2022 | 3 | 1 | 4 |
| 2023 | 1 | 6 | 7 |
| 2024 | 0 | 2 | 2 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Inflammasomes" by people in Profiles.
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Mitigation of nicotine-induced podocyte injury through inhibition of thioredoxin interacting protein. Biomed Pharmacother. 2025 Jun; 187:118110.
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IRE1a silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer. Cell. 2024 Dec 12; 187(25):7248-7266.e34.
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Mitochondrial (mt)DNA-cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling promotes pyroptosis of macrophages via interferon regulatory factor (IRF)7/IRF3 activation to aggravate lung injury during severe acute pancreatitis. Cell Mol Biol Lett. 2024 Apr 27; 29(1):61.
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A High-Protein Diet Promotes Atrial Arrhythmogenesis via Absent-in-Melanoma 2 Inflammasome. Cells. 2024 01 05; 13(2).
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Contribution of membrane raft redox signalling to visfatin-induced inflammasome activation and podocyte injury. Aging (Albany NY). 2023 11 17; 15(22):12738-12748.
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Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation. J Clin Invest. 2023 10 02; 133(19).
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The genetic and clinical characteristics and effects of Canakinumab on cryopyrin-associated periodic syndrome: a large pediatric cohort study from China. Front Immunol. 2023; 14:1267933.
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No NLRP3 inflammasome activity in kidney epithelial cells, not even when the NLRP3-A350V Muckle-Wells variant is expressed in podocytes of diabetic mice. Front Immunol. 2023; 14:1230050.
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Oleoylethanolamide facilitates PPARa and TFEB signaling and attenuates A? pathology in a mouse model of Alzheimer's disease. Mol Neurodegener. 2023 08 15; 18(1):56.
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NLRP3 agonist enhances radiation-induced immune priming and promotes abscopal responses in anti-PD1 resistant model. Cancer Immunol Immunother. 2023 Sep; 72(9):3003-3012.