"Receptor, Adenosine A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of tissues including the BRAIN and DORSAL HORN NEURONS. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.
| Descriptor ID |
D043682
|
| MeSH Number(s) |
D12.776.543.750.695.700.700.100 D12.776.543.750.720.700.700.100
|
| Concept/Terms |
Receptor, Adenosine A1- Receptor, Adenosine A1
- Adenosine A1 Receptors
- Receptors, Adenosine A1
- Adenosine A1 Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Adenosine A1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P1 [D12.776.543.750.695.700.700]
- Receptor, Adenosine A1 [D12.776.543.750.695.700.700.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P1 [D12.776.543.750.720.700.700]
- Receptor, Adenosine A1 [D12.776.543.750.720.700.700.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Adenosine A1".
This graph shows the total number of publications written about "Receptor, Adenosine A1" by people in this website by year, and whether "Receptor, Adenosine A1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Receptor, Adenosine A1" by people in Profiles.
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Single exercise stress reduces central neurotrophins levels and adenosine A1 and A2 receptors expression, but does not revert opioid-induced hyperalgesia in rats. Int J Dev Neurosci. 2020 Nov; 80(7):636-647.
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ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis. Cancer Cell. 2020 03 16; 37(3):324-339.e8.
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Chronic treatment with ticagrelor limits myocardial infarct size: an adenosine and cyclooxygenase-2-dependent effect. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2078-85.
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Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels. J Neurochem. 2010 Apr; 113(2):530-42.