Transcription Factor 7-Like 1 Protein
"Transcription Factor 7-Like 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that takes part in WNT signaling pathway where it may play a role in the differentiation of KERATINOCYTES. The transcriptional activity of this protein is regulated via its interaction with BETA CATENIN.
| Descriptor ID |
D058125
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| MeSH Number(s) |
D12.776.260.730.812 D12.776.660.235.400.800.812 D12.776.664.235.400.800.812 D12.776.930.875.812
|
| Concept/Terms |
Transcription Factor 7-Like 1 Protein- Transcription Factor 7-Like 1 Protein
- Transcription Factor 7 Like 1 Protein
- TCF7L1 Transcription Factor
- Transcription Factor, TCF7L1
- TCF-3 Transcription Factor
- TCF 3 Transcription Factor
- Transcription Factor, TCF-3
- HMG Box Transcription Factor 3
- T Cell Factor 3
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor 7-Like 1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor 7-Like 1 Protein".
This graph shows the total number of publications written about "Transcription Factor 7-Like 1 Protein" by people in this website by year, and whether "Transcription Factor 7-Like 1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Transcription Factor 7-Like 1 Protein" by people in Profiles.
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The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency. Nat Commun. 2023 03 03; 14(1):1210.
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Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12182-12191.
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TCF7L1 promotes skin tumorigenesis independently of ?-catenin through induction of LCN2. Elife. 2017 05 03; 6.
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The Sox4/Tcf7l1 axis promotes progression of BCR-ABL-positive acute lymphoblastic leukemia. Haematologica. 2014 Oct; 99(10):1591-8.
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CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res. 2013 Sep; 23(9):1446-61.
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Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia. Nat Genet. 2009 Oct; 41(10):1068-75.
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Tcf3 governs stem cell features and represses cell fate determination in skin. Cell. 2006 Oct 06; 127(1):171-83.
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Notch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination. Mol Cell Biol. 2004 Oct; 24(20):8951-62.
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Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD. Mol Endocrinol. 2004 Apr; 18(4):776-90.
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Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities. EMBO J. 2003 Nov 03; 22(21):5780-92.