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Sung Yun Jung

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Biochemistry & Molecular Biology
DivisionBiochemistry & Molecular Biology
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


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    R01AR053349     (HAMILTON, SUSAN L)Dec 1, 2005 - Mar 31, 2021
    NIH/NIAMS
    Basis of Muscle Dysfunction in Malignant Hyperthermia & Central Core Disease
    Role: Co-Principal Investigator

    R01AR072475     (HAMILTON, SUSAN L)Mar 22, 2018 - Feb 28, 2023
    NIH/NIAMS
    Redefining the Role of FKBP12 in Skeletal Muscle
    Role: Co-Principal Investigator

    R01AR072602     (HAMILTON, SUSAN L)Aug 1, 2018 - Jun 30, 2023
    NIH/NIAMS
    Mechanisms of couplon-linked skeletal muscle myopathies
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mikheeva SA, Camp ND, Huang L, Jain A, Jung SY, Avci NG, Tokita M, Wolf-Yadlin A, Zhang J, Tapscott SJ, Rostomily RC, Mikheev AM. TWIST1 Heterodimerization with E12 Requires Coordinated Protein Phosphorylation to Regulate Periostin Expression. Cancers (Basel). 2019 Sep 18; 11(9). PMID: 31540485.
      View in: PubMed
    2. Chen Y, Leng M, Gao Y, Zhan D, Choi JM, Song L, Li K, Xia X, Zhang C, Liu M, Ji S, Jain A, Saltzman AB, Malovannaya A, Qin J, Jung SY, Wang Y. A Cross-Linking-Aided Immunoprecipitation/Mass Spectrometry Workflow Reveals Extensive Intracellular Trafficking in Time-Resolved, Signal-Dependent Epidermal Growth Factor Receptor Proteome. J Proteome Res. 2019 Oct 04; 18(10):3715-3730. PMID: 31442056.
      View in: PubMed
    3. Park YY, Jung SY, Jennings NB, Rodriguez-Aguayo C, Peng G, Lee SR, Kim SB, Kim K, Leem SH, Lin SY, Lopez-Berestein G, Sood AK, Lee JS. Corrigendum: FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair. Carcinogenesis. 2019 Jul 20; 40(7):936. PMID: 31063534.
      View in: PubMed
    4. Farkas Z, Petric M, Liu X, Herit F, Rajnavölgyi É, Szondy Z, Budai Z, Orbán TI, Sándor S, Mehta A, Bajtay Z, Kovács T, Jung SY, Afaq Shakir M, Qin J, Zhou Z, Niedergang F, Boissan M, Takács-Vellai K. The nucleoside diphosphate kinase NDK-1/NME1 promotes phagocytosis in concert with DYN-1/Dynamin. FASEB J. 2019 Oct; 33(10):11606-11614. PMID: 31242766.
      View in: PubMed
    5. Huichalaf CH, Al-Ramahi I, Park KW, Grunke SD, Lu N, de Haro M, El-Zein K, Gallego-Flores T, Perez AM, Jung SY, Botas J, Zoghbi HY, Jankowsky JL. Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease. Hum Mol Genet. 2019 06 15; 28(12):2014-2029. PMID: 30753434.
      View in: PubMed
    6. Lee YC, Kurtova AV, Xiao J, Nikolos F, Hayashi K, Tramel Z, Jain A, Chen F, Chokshi M, Lee C, Bao G, Zhang X, Shen J, Mo Q, Jung SY, Rowley D, Chan KS. Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung. Nat Commun. 2019 05 13; 10(1):2131. PMID: 31086186.
      View in: PubMed
    7. Bertolet G, Kongchan N, Miller R, Patel RK, Jain A, Choi JM, Saltzman AB, Christenson A, Jung SY, Malovannaya A, Grimson A, Neilson JR. MiR-146a wild-type 3' sequence identity is dispensable for proper innate immune function in vivo. Life Sci Alliance. 2019 02; 2(1). PMID: 30777858.
      View in: PubMed
    8. Chen Z, Lei C, Wang C, Li N, Srivastava M, Tang M, Zhang H, Choi JM, Jung SY, Qin J, Chen J. Global phosphoproteomic analysis reveals ARMC10 as an AMPK substrate that regulates mitochondrial dynamics. Nat Commun. 2019 01 10; 10(1):104. PMID: 30631047.
      View in: PubMed
    9. Srivastava M, Chen Z, Zhang H, Tang M, Wang C, Jung SY, Chen J. Replisome Dynamics and Their Functional Relevance upon DNA Damage through the PCNA Interactome. Cell Rep. 2018 12 26; 25(13):3869-3883.e4. PMID: 30590055.
      View in: PubMed
    10. Ahn JH, Lee HS, Lee JS, Lee YS, Park JL, Kim SY, Hwang JA, Kunkeaw N, Jung SY, Kim TJ, Lee KS, Jeon SH, Lee I, Johnson BH, Choi JH, Lee YS. Author Correction: nc886 is induced by TGF-ß and suppresses the microRNA pathway in ovarian cancer. Nat Commun. 2018 12 19; 9(1):5458. PMID: 30568190.
      View in: PubMed
    11. Kim KH, Choi JM, Li F, Dong B, Wooton-Kee CR, Arizpe A, Anakk S, Jung SY, Hartig SM, Moore DD. Constitutive Androstane Receptor Differentially Regulates Bile Acid Homeostasis in Mouse Models of Intrahepatic Cholestasis. Hepatol Commun. 2019 Jan; 3(1):147-159. PMID: 30620001.
      View in: PubMed
    12. Yu C, Tang J, Loredo A, Chen Y, Jung SY, Jain A, Gordon A, Xiao H. Proximity-Induced Site-Specific Antibody Conjugation. Bioconjug Chem. 2018 11 21; 29(11):3522-3526. PMID: 30372039.
      View in: PubMed
    13. Choi BK, Dayaram T, Parikh N, Wilkins AD, Nagarajan M, Novikov IB, Bachman BJ, Jung SY, Haas PJ, Labrie JL, Pickering CR, Adikesavan AK, Regenbogen S, Kato L, Lelescu A, Buchovecky CM, Zhang H, Bao SH, Boyer S, Weber G, Scott KL, Chen Y, Spangler S, Donehower LA, Lichtarge O. Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2. Proc Natl Acad Sci U S A. 2018 10 16; 115(42):10666-10671. PMID: 30266789.
      View in: PubMed
    14. Dharmat R, Eblimit A, Robichaux MA, Zhang Z, Nguyen TT, Jung SY, He F, Jain A, Li Y, Qin J, Overbeek P, Roepman R, Mardon G, Wensel TG, Chen R. SPATA7 maintains a novel photoreceptor-specific zone in the distal connecting cilium. J Cell Biol. 2018 08 06; 217(8):2851-2865. PMID: 29899041.
      View in: PubMed
    15. Kim KH, Choi JM, Li F, Arizpe A, Wooton-Kee CR, Anakk S, Jung SY, Finegold MJ, Moore DD. Xenobiotic Nuclear Receptor Signaling Determines Molecular Pathogenesis of Progressive Familial Intrahepatic Cholestasis. Endocrinology. 2018 06 01; 159(6):2435-2446. PMID: 29718219.
      View in: PubMed
    16. Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, Ellis MJ, Rosen JM. FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation. Cancer Res. 2018 08 01; 78(15):4229-4240. PMID: 29844125.
      View in: PubMed
    17. Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, Jung SY, Malovannaya A, Li S, Shao J, Roeder RG, Ellis MJ, Qin J, Fuqua SAW, O'Malley BW, Foulds CE. Proteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets. Oncogene. 2018 08; 37(33):4581-4598. PMID: 29748621.
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    18. Ge S, Xia X, Ding C, Zhen B, Zhou Q, Feng J, Yuan J, Chen R, Li Y, Ge Z, Ji J, Zhang L, Wang J, Li Z, Lai Y, Hu Y, Li Y, Li Y, Gao J, Chen L, Xu J, Zhang C, Jung SY, Choi JM, Jain A, Liu M, Song L, Liu W, Guo G, Gong T, Huang Y, Qiu Y, Huang W, Shi T, Zhu W, Wang Y, He F, Shen L, Qin J. Author Correction: A proteomic landscape of diffuse-type gastric cancer. Nat Commun. 2018 05 08; 9(1):1850. PMID: 29739932.
      View in: PubMed
    19. Ferreon JC, Jain A, Choi KJ, Tsoi PS, MacKenzie KR, Jung SY, Ferreon AC. Acetylation Disfavors Tau Phase Separation. Int J Mol Sci. 2018 May 04; 19(5). PMID: 29734651.
      View in: PubMed
    20. Lee HS, Jang HJ, Choi JM, Zhang J, de Rosen VL, Wheeler TM, Lee JS, Tu T, Jindra PT, Kerman RH, Jung SY, Kheradmand F, Sugarbaker DJ, Burt BM. Comprehensive immunoproteogenomic analyses of malignant pleural mesothelioma. JCI Insight. 2018 04 05; 3(7). PMID: 29618661.
      View in: PubMed
    21. Ahn JH, Lee HS, Lee JS, Lee YS, Park JL, Kim SY, Hwang JA, Kunkeaw N, Jung SY, Kim TJ, Lee KS, Jeon SH, Lee I, Johnson BH, Choi JH, Lee YS. nc886 is induced by TGF-ß and suppresses the microRNA pathway in ovarian cancer. Nat Commun. 2018 03 21; 9(1):1166. PMID: 29563500.
      View in: PubMed
    22. Ge S, Xia X, Ding C, Zhen B, Zhou Q, Feng J, Yuan J, Chen R, Li Y, Ge Z, Ji J, Zhang L, Wang J, Li Z, Lai Y, Hu Y, Li Y, Li Y, Gao J, Chen L, Xu J, Zhang C, Jung SY, Choi JM, Jain A, Liu M, Song L, Liu W, Guo G, Gong T, Huang Y, Qiu Y, Huang W, Shi T, Zhu W, Wang Y, He F, Shen L, Qin J. A proteomic landscape of diffuse-type gastric cancer. Nat Commun. 2018 03 08; 9(1):1012. PMID: 29520031.
      View in: PubMed
    23. Zhang C, Chen Y, Mao X, Huang Y, Jung SY, Jain A, Qin J, Wang Y. A Bioinformatic Algorithm for Analyzing Cell Signaling Using Temporal Proteomic Data. Proteomics. 2017 Nov; 17(22). PMID: 28940701.
      View in: PubMed
    24. Tsai WC, Reineke LC, Jain A, Jung SY, Lloyd RE. Histone arginine demethylase JMJD6 is linked to stress granule assembly through demethylation of the stress granule-nucleating protein G3BP1. J Biol Chem. 2017 11 17; 292(46):18886-18896. PMID: 28972166.
      View in: PubMed
    25. Zhang Z, Nikolai BC, Gates LA, Jung SY, Siwak EB, He B, Rice AP, O'Malley BW, Feng Q. Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency. Nucleic Acids Res. 2017 Sep 19; 45(16):9348-9360. PMID: 28637181.
      View in: PubMed
    26. San Martin R, Pathak R, Jain A, Jung SY, Hilsenbeck SG, Piña-Barba MC, Sikora AG, Pienta KJ, Rowley DR. Tenascin-C and Integrin a9 Mediate Interactions of Prostate Cancer with the Bone Microenvironment. Cancer Res. 2017 11 01; 77(21):5977-5988. PMID: 28916657.
      View in: PubMed
    27. Gates LA, Shi J, Rohira AD, Feng Q, Zhu B, Bedford MT, Sagum CA, Jung SY, Qin J, Tsai MJ, Tsai SY, Li W, Foulds CE, O'Malley BW. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017 09 01; 292(35):14456-14472. PMID: 28717009.
      View in: PubMed
    28. Kim BJ, Chan DW, Jung SY, Chen Y, Qin J, Wang Y. The Histone Variant MacroH2A1 Is a BRCA1 Ubiquitin Ligase Substrate. Cell Rep. 2017 05 30; 19(9):1758-1766. PMID: 28564596.
      View in: PubMed
    29. Leng W, Ni X, Sun C, Lu T, Malovannaya A, Jung SY, Huang Y, Qiu Y, Sun G, Holt MV, Ding C, Sun W, Men X, Shi T, Zhu W, Wang Y, He F, Zhen B, Wang G, Qin J. Proof-of-Concept Workflow for Establishing Reference Intervals of Human Urine Proteome for Monitoring Physiological and Pathological Changes. EBioMedicine. 2017 Apr; 18:300-310. PMID: 28396014.
      View in: PubMed
    30. Li X, Gao M, Choi JM, Kim BJ, Zhou MT, Chen Z, Jain AN, Jung SY, Yuan J, Wang W, Wang Y, Chen J. Clustered, Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9-coupled Affinity Purification/Mass Spectrometry Analysis Revealed a Novel Role of Neurofibromin in mTOR Signaling. Mol Cell Proteomics. 2017 04; 16(4):594-607. PMID: 28174230.
      View in: PubMed
    31. Jung SY, Choi JM, Rousseaux MW, Malovannaya A, Kim JJ, Kutzera J, Wang Y, Huang Y, Zhu W, Maity S, Zoghbi HY, Qin J. An Anatomically Resolved Mouse Brain Proteome Reveals Parkinson Disease-relevant Pathways. Mol Cell Proteomics. 2017 04; 16(4):581-593. PMID: 28153913.
      View in: PubMed
    32. Reineke LC, Tsai WC, Jain A, Kaelber JT, Jung SY, Lloyd RE. Casein Kinase 2 Is Linked to Stress Granule Dynamics through Phosphorylation of the Stress Granule Nucleating Protein G3BP1. Mol Cell Biol. 2017 02 15; 37(4). PMID: 27920254.
      View in: PubMed
    33. Xiao L, Lanz RB, Frolov A, Castro PD, Zhang Z, Dong B, Xue W, Jung SY, Lydon JP, Edwards DP, Mancini MA, Feng Q, Ittmann MM, He B. The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker. Prostate. 2016 10; 76(14):1271-84. PMID: 27272765.
      View in: PubMed
    34. Zhao L, Chen Y, Bajaj AO, Eblimit A, Xu M, Soens ZT, Wang F, Ge Z, Jung SY, He F, Li Y, Wensel TG, Qin J, Chen R. Integrative subcellular proteomic analysis allows accurate prediction of human disease-causing genes. Genome Res. 2016 05; 26(5):660-9. PMID: 26912414.
      View in: PubMed
    35. Han SJ, Jung SY, Wu SP, Hawkins SM, Park MJ, Kyo S, Qin J, Lydon JP, Tsai SY, Tsai MJ, DeMayo FJ, O'Malley BW. Estrogen Receptor ß Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 05; 163(4):960-74. PMID: 26544941.
      View in: PubMed
    36. Liu T, Lin YH, Leng W, Jung SY, Zhang H, Deng M, Evans D, Li Y, Luo K, Qin B, Qin J, Yuan J, Lou Z. A divergent role of the SIRT1-TopBP1 axis in regulating metabolic checkpoint and DNA damage checkpoint. Mol Cell. 2014 Dec 04; 56(5):681-95. PMID: 25454945.
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    37. Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE. Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte. PLoS One. 2014; 9(6):e100660. PMID: 24949636.
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    38. Liu B, Badeaux MD, Choy G, Chandra D, Shen I, Jeter CR, Rycaj K, Lee CF, Person MD, Liu C, Chen Y, Shen J, Jung SY, Qin J, Tang DG. Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species. PLoS One. 2014; 9(3):e90615. PMID: 24598770.
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    39. Kang YK, Jung SY, Qin J, Li C, Tsai SY, Tsai MJ, O'Malley BW. E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity. Mol Cell Biol. 2014 May; 34(9):1670-81. PMID: 24567374.
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    40. Carroll C, Bansbach CE, Zhao R, Jung SY, Qin J, Cortez D. Phosphorylation of a C-terminal auto-inhibitory domain increases SMARCAL1 activity. Nucleic Acids Res. 2014 Jan; 42(2):918-25. PMID: 24150942.
      View in: PubMed
    41. Couch FB, Bansbach CE, Driscoll R, Luzwick JW, Glick GG, Bétous R, Carroll CM, Jung SY, Qin J, Cimprich KA, Cortez D. ATR phosphorylates SMARCAL1 to prevent replication fork collapse. Genes Dev. 2013 Jul 15; 27(14):1610-23. PMID: 23873943.
      View in: PubMed
    42. Ahn KH, Kim SK, Choi JM, Jung SY, Won JH, Back MJ, Fu Z, Jang JM, Ha HC, Kim DK. Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine Uptake. PLoS One. 2013; 8(6):e67216. PMID: 23840630.
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    43. Liu J, Wang Y, Li L, Zhou L, Wei H, Zhou Q, Liu J, Wang W, Ji L, Shan P, Wang Y, Yang Y, Jung SY, Zhang P, Wang C, Long W, Zhang B, Li X. Site-specific acetylation of the proteasome activator REG? directs its heptameric structure and functions. J Biol Chem. 2013 Jun 07; 288(23):16567-78. PMID: 23612972.
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    44. Ding C, Chan DW, Liu W, Liu M, Li D, Song L, Li C, Jin J, Malovannaya A, Jung SY, Zhen B, Wang Y, Qin J. Proteome-wide profiling of activated transcription factors with a concatenated tandem array of transcription factor response elements. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6771-6. PMID: 23553833.
      View in: PubMed
    45. Han SJ, Hawkins SM, Begum K, Jung SY, Kovanci E, Qin J, Lydon JP, DeMayo FJ, O'Malley BW. A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med. 2012 Jul; 18(7):1102-11. PMID: 22660634.
      View in: PubMed
    46. Park YY, Jung SY, Jennings NB, Rodriguez-Aguayo C, Peng G, Lee SR, Kim SB, Kim K, Leem SH, Lin SY, Lopez-Berestein G, Sood AK, Lee JS. FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair. Carcinogenesis. 2012 Oct; 33(10):1843-53. PMID: 22581827.
      View in: PubMed
    47. Al-Tawashi A, Jung SY, Liu D, Su B, Qin J. Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity. J Biol Chem. 2012 Apr 27; 287(18):14644-58. PMID: 22375002.
      View in: PubMed
    48. Dai C, Tang Y, Jung SY, Qin J, Aaronson SA, Gu W. Differential effects on p53-mediated cell cycle arrest vs. apoptosis by p90. Proc Natl Acad Sci U S A. 2011 Nov 22; 108(47):18937-42. PMID: 22084066.
      View in: PubMed
    49. Leem YE, Choi HK, Jung SY, Kim BJ, Lee KY, Yoon K, Qin J, Kang JS, Kim ST. Esco2 promotes neuronal differentiation by repressing Notch signaling. Cell Signal. 2011 Nov; 23(11):1876-84. PMID: 21777673.
      View in: PubMed
    50. Ding C, Li Y, Kim BJ, Malovannaya A, Jung SY, Wang Y, Qin J. Quantitative analysis of cohesin complex stoichiometry and SMC3 modification-dependent protein interactions. J Proteome Res. 2011 Aug 05; 10(8):3652-9. PMID: 21699228.
      View in: PubMed
    51. Zhang Z, Kim T, Bao M, Facchinetti V, Jung SY, Ghaffari AA, Qin J, Cheng G, Liu YJ. DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells. Immunity. 2011 Jun 24; 34(6):866-78. PMID: 21703541.
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    52. King KY, Baldridge MT, Weksberg DC, Chambers SM, Lukov GL, Wu S, Boles NC, Jung SY, Qin J, Liu D, Songyang Z, Eissa NT, Taylor GA, Goodell MA. Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood. 2011 Aug 11; 118(6):1525-33. PMID: 21633090.
      View in: PubMed
    53. Malovannaya A, Lanz RB, Jung SY, Bulynko Y, Le NT, Chan DW, Ding C, Shi Y, Yucer N, Krenciute G, Kim BJ, Li C, Chen R, Li W, Wang Y, O'Malley BW, Qin J. Analysis of the human endogenous coregulator complexome. Cell. 2011 May 27; 145(5):787-99. PMID: 21620140.
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    54. Ji JE, Kim SK, Ahn KH, Choi JM, Jung SY, Jung KM, Jeon HJ, Kim DK. Ceramide induces serotonin release from RBL-2H3 mast cells through calcium mediated activation of phospholipase A2. Prostaglandins Other Lipid Mediat. 2011 Apr; 94(3-4):88-95. PMID: 21236359.
      View in: PubMed
    55. Kumar M, Jung SY, Hodgson AJ, Madden CR, Qin J, Slagle BL. Hepatitis B virus regulatory HBx protein binds to adaptor protein IPS-1 and inhibits the activation of beta interferon. J Virol. 2011 Jan; 85(2):987-95. PMID: 21068253.
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    56. Wang R, Jung SY, Wu CF, Qin J, Kobayashi R, Gallick GE, Kuang J. Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):19885-90. PMID: 21041626.
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    57. Shi Y, Chan DW, Jung SY, Malovannaya A, Wang Y, Qin J. A data set of human endogenous protein ubiquitination sites. Mol Cell Proteomics. 2011 May; 10(5):M110.002089. PMID: 20972266.
      View in: PubMed
    58. Kim BJ, Li Y, Zhang J, Xi Y, Li Y, Yang T, Jung SY, Pan X, Chen R, Li W, Wang Y, Qin J. Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cells. J Biol Chem. 2010 Jul 23; 285(30):22784-92. PMID: 20501661.
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    59. Wu CF, Wang R, Liang Q, Liang J, Li W, Jung SY, Qin J, Lin SH, Kuang J. Dissecting the M phase-specific phosphorylation of serine-proline or threonine-proline motifs. Mol Biol Cell. 2010 May 01; 21(9):1470-81. PMID: 20219976.
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    60. Fu X, Yucer N, Liu S, Li M, Yi P, Mu JJ, Yang T, Chu J, Jung SY, O'Malley BW, Gu W, Qin J, Wang Y. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4579-84. PMID: 20173098.
      View in: PubMed
    61. Malovannaya A, Li Y, Bulynko Y, Jung SY, Wang Y, Lanz RB, O'Malley BW, Qin J. Streamlined analysis schema for high-throughput identification of endogenous protein complexes. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2431-6. PMID: 20133760.
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    62. Kim SK, Ahn KH, Ji JE, Choi JM, Jeon HJ, Jung SY, Jung KM, Kim DK. Neutral sphingomyelinase 2 induces dopamine uptake through regulation of intracellular calcium. Cell Signal. 2010 May; 22(5):865-70. PMID: 20096352.
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    63. Kang MS, Ahn KH, Kim SK, Jeon HJ, Ji JE, Choi JM, Jung KM, Jung SY, Kim DK. Hypoxia-induced neuronal apoptosis is mediated by de novo synthesis of ceramide through activation of serine palmitoyltransferase. Cell Signal. 2010 Apr; 22(4):610-8. PMID: 19932170.
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    64. Feng Q, He B, Jung SY, Song Y, Qin J, Tsai SY, Tsai MJ, O'Malley BW. Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem. 2009 Dec 25; 284(52):36167-74. PMID: 19843527.
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    65. Allton K, Jain AK, Herz HM, Tsai WW, Jung SY, Qin J, Bergmann A, Johnson RL, Barton MC. Trim24 targets endogenous p53 for degradation. Proc Natl Acad Sci U S A. 2009 Jul 14; 106(28):11612-6. PMID: 19556538.
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    66. Zhang J, Shi X, Li Y, Kim BJ, Jia J, Huang Z, Yang T, Fu X, Jung SY, Wang Y, Zhang P, Kim ST, Pan X, Qin J. Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast. Mol Cell. 2008 Jul 11; 31(1):143-51. PMID: 18614053.
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    67. Chahrour M, Jung SY, Shaw C, Zhou X, Wong ST, Qin J, Zoghbi HY. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science. 2008 May 30; 320(5880):1224-9. PMID: 18511691.
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    68. Kim BJ, Kang KM, Jung SY, Choi HK, Seo JH, Chae JH, Cho EJ, Youn HD, Qin J, Kim ST. Esco2 is a novel corepressor that associates with various chromatin modifying enzymes. Biochem Biophys Res Commun. 2008 Jul 25; 372(2):298-304. PMID: 18501190.
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    69. Liang J, Wan M, Zhang Y, Gu P, Xin H, Jung SY, Qin J, Wong J, Cooney AJ, Liu D, Songyang Z. Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat Cell Biol. 2008 Jun; 10(6):731-9. PMID: 18454139.
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    70. Luo H, Li Y, Mu JJ, Zhang J, Tonaka T, Hamamori Y, Jung SY, Wang Y, Qin J. Regulation of intra-S phase checkpoint by ionizing radiation (IR)-dependent and IR-independent phosphorylation of SMC3. J Biol Chem. 2008 Jul 11; 283(28):19176-83. PMID: 18442975.
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    71. Leng M, Besusso D, Jung SY, Wang Y, Qin J. Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase. Cell Cycle. 2008 05 15; 7(10):1480-9. PMID: 18418076.
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    72. Jung SY, Li Y, Wang Y, Chen Y, Zhao Y, Qin J. Complications in the assignment of 14 and 28 Da mass shift detected by mass spectrometry as in vivo methylation from endogenous proteins. Anal Chem. 2008 Mar 01; 80(5):1721-9. PMID: 18247584.
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    73. Zhao W, Kruse JP, Tang Y, Jung SY, Qin J, Gu W. Negative regulation of the deacetylase SIRT1 by DBC1. Nature. 2008 Jan 31; 451(7178):587-90. PMID: 18235502.
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    74. Mu JJ, Wang Y, Luo H, Leng M, Zhang J, Yang T, Besusso D, Jung SY, Qin J. A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints. J Biol Chem. 2007 Jun 15; 282(24):17330-4. PMID: 17478428.
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    75. Daquinag A, Fadri M, Jung SY, Qin J, Kunz J. The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress. Mol Cell Biol. 2007 Jan; 27(2):633-50. PMID: 17101780.
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    76. Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell. 2006 Oct 06; 127(1):125-37. PMID: 16962653.
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    77. Han SJ, Jung SY, Malovannaya A, Kim T, Lanz RB, Qin J, O'Malley BW. A scoring system for the follow up study of nuclear receptor coactivator complexes. Nucl Recept Signal. 2006; 4:e014. PMID: 16862220.
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    78. Li X, Lonard DM, Jung SY, Malovannaya A, Feng Q, Qin J, Tsai SY, Tsai MJ, O'Malley BW. The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell. 2006 Jan 27; 124(2):381-92. PMID: 16439211.
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    79. Jung SY, Malovannaya A, Wei J, O'Malley BW, Qin J. Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. Mol Endocrinol. 2005 Oct; 19(10):2451-65. PMID: 16051665.
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    80. Lee HW, Choe YH, Kim DK, Jung SY, Lee NG. Proteomic analysis of a ferric uptake regulator mutant of Helicobacter pylori: regulation of Helicobacter pylori gene expression by ferric uptake regulator and iron. Proteomics. 2004 Jul; 4(7):2014-27. PMID: 15221763.
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    81. Jung DJ, Sung HS, Goo YW, Lee HM, Park OK, Jung SY, Lim J, Kim HJ, Lee SK, Kim TS, Lee JW, Lee YC. Novel transcription coactivator complex containing activating signal cointegrator 1. Mol Cell Biol. 2002 Jul; 22(14):5203-11. PMID: 12077347.
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