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ROY SILLITOE

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
Address1250 MOURSUND STREET
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pediatrics
    DivisionPediatrics-Neurology


    Collapse Research 
    Collapse research activities and funding
    R13NS132567     (SILLITOE, ROY VINCENT)May 15, 2023 - Apr 30, 2024
    NIH
    2023 Cerebellum Gordon Research Conference and Gordon Research Seminar
    Role: Principal Investigator
    R01NS119301     (SILLITOE, ROY VINCENT)Sep 30, 2020 - Aug 31, 2025
    NIH
    Cerebellar Deep Brain Stimulation
    Role: Principal Investigator
    R01NS100874     (SILLITOE, ROY VINCENT)Sep 25, 2017 - Jun 30, 2022
    NIH
    CEREBELLAR FUNCTION IN TREMOR
    Role: Principal Investigator
    R01NS089664     (SILLITOE, ROY VINCENT)Sep 30, 2014 - Jun 30, 2021
    NIH
    SYNAPTIC ORIGINS OF CEREBELLAR DISEASE
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Leon LES, Brown AM, Kaku H, Sillitoe RV. Purkinje cell dysfunction causes disrupted sleep in ataxic mice. Dis Model Mech. 2024 Apr 02. PMID: 38563553.
      Citations:    Fields:    
    2. Raghubar KP, Heitzer AM, Malbari F, Gill J, Sillitoe RV, Merrill L, Escalante J, Okcu MF, Aldave G, Meoded A, Kralik S, Davis K, Ma M, Warren EAH, McCurdy MD, Weiner HL, Whitehead W, Scheurer ME, Rodriguez L, Daigle A, Chintagumpala M, Kahalley LS. Adaptive, behavioral, and emotional outcomes following postoperative pediatric cerebellar mutism syndrome in survivors treated for medulloblastoma. J Neurosurg Pediatr. 2024 Mar 29; 1-8. PMID: 38552237.
      Citations:    Fields:    
    3. Gittis AH, Sillitoe RV. Circuit-Specific Deep Brain Stimulation Provides Insights into Movement Control. Annu Rev Neurosci. 2024 Feb 29. PMID: 38424473.
      Citations:    Fields:    
    4. Beckinghausen J, Ortiz-Guzman J, Lin T, Bachman B, Salazar Leon LE, Liu Y, Heck DH, Arenkiel BR, Sillitoe RV. Author Correction: The cerebellum contributes to generalized seizures by altering activity in the ventral posteromedial nucleus. Commun Biol. 2024 Feb 16; 7(1):186. PMID: 38365939; PMCID: PMC10873329.
      Citations:    
    5. Gill JS, Nguyen MX, Hull M, van der Heijden ME, Nguyen K, Thomas SP, Sillitoe RV. Function and dysfunction of the dystonia network: an exploration of neural circuits that underlie the acquired and isolated dystonias. Dystonia. 2023; 2. PMID: 38273865; PMCID: PMC10810232.
      Citations:    
    6. van der Heijden ME, Sillitoe RV. Cerebellar dysfunction in rodent models with dystonia, tremor, and ataxia. Dystonia. 2023; 2. PMID: 38105800; PMCID: PMC10722573.
      Citations:    
    7. Leon LES, Kim LH, Sillitoe RV. Cerebellar deep brain stimulation as a dual-function therapeutic for restoring movement and sleep in dystonic mice. bioRxiv. 2023 Nov 02. PMID: 37961355; PMCID: PMC10635001.
      Citations:    
    8. van der Heijden ME, Brown AM, Kizek DJ, Sillitoe RV. Neural spiking signatures predict behavioral phenotypes of cerebellar movement disorders. bioRxiv. 2023 Aug 19. PMID: 37214855; PMCID: PMC10197583.
      Citations:    
    9. Beckinghausen J, Ortiz-Guzman J, Lin T, Bachman B, Salazar Leon LE, Liu Y, Heck DH, Arenkiel BR, Sillitoe RV. The cerebellum contributes to generalized seizures by altering activity in the ventral posteromedial nucleus. Commun Biol. 2023 07 15; 6(1):731. PMID: 37454228; PMCID: PMC10349834.
      Citations:    Translation:Animals
    10. Salazar Leon LE, Brown AM, Kaku H, Sillitoe RV. Purkinje cell dysfunction causes disrupted sleep in ataxic mice. bioRxiv. 2023 Jul 03. PMID: 37461479; PMCID: PMC10350025.
      Citations:    
    11. Rey Hipolito AG, van der Heijden ME, Sillitoe RV. Physiology of Dystonia: Animal Studies. Int Rev Neurobiol. 2023; 169:163-215. PMID: 37482392.
      Citations: 1     Fields:    Translation:Animals
    12. van der Heijden ME, Rey Hipolito AG, Kim LH, Kizek DJ, Perez RM, Lin T, Sillitoe RV. Glutamatergic cerebellar neurons differentially contribute to the acquisition of motor and social behaviors. Nat Commun. 2023 05 15; 14(1):2771. PMID: 37188723; PMCID: PMC10185563.
      Citations:    Fields:    Translation:AnimalsCells
    13. Coffin SL, Durham MA, Nitschke L, Xhako E, Brown AM, Revelli JP, Villavicencio Gonzalez E, Lin T, Handler HP, Dai Y, Trostle AJ, Wan YW, Liu Z, Sillitoe RV, Orr HT, Zoghbi HY. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron. 2023 Mar 15; 111(6):915. PMID: 36924764; PMCID: PMC10153637.
      Citations: 1     Fields:    
    14. Leon LES, Sillitoe RV. Disrupted sleep in dystonia depends on cerebellar function but not motor symptoms in mice. bioRxiv. 2023 Feb 10. PMID: 36798256; PMCID: PMC9934608.
      Citations:    
    15. Wong JK, Mayberg HS, Wang DD, Richardson RM, Halpern CH, Krinke L, Arlotti M, Rossi L, Priori A, Marceglia S, Gilron R, Cavanagh JF, Judy JW, Miocinovic S, Devergnas AD, Sillitoe RV, Cernera S, Oehrn CR, Gunduz A, Goodman WK, Petersen EA, Bronte-Stewart H, Raike RS, Malekmohammadi M, Greene D, Heiden P, Tan H, Volkmann J, Voon V, Li L, Sah P, Coyne T, Silburn PA, Kubu CS, Wexler A, Chandler J, Provenza NR, Heilbronner SR, Luciano MS, Rozell CJ, Fox MD, de Hemptinne C, Henderson JM, Sheth SA, Okun MS. Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation. Front Hum Neurosci. 2022; 16:1084782. PMID: 36819295; PMCID: PMC9933515.
      Citations: 1     
    16. Brown AM, Lackey EP, Salazar Leon LE, Rey Hipolito AG, Beckinghausen J, Lin T, Sillitoe RV. Electromyography as a Method for Distinguishing Dystonia in Mice. Adv Neurobiol. 2023; 31:71-91. PMID: 37338697.
      Citations:    Fields:    Translation:Animals
    17. Beckinghausen J, Donofrio SG, Lin T, Miterko LN, White JJ, Lackey EP, Sillitoe RV. Deep Brain Stimulation of the Interposed Cerebellar Nuclei in a Conditional Genetic Mouse Model with Dystonia. Adv Neurobiol. 2023; 31:93-117. PMID: 37338698.
      Citations:    Fields:    Translation:Animals
    18. Coffin SL, Durham MA, Nitschke L, Xhako E, Brown AM, Revelli JP, Villavicencio Gonzalez E, Lin T, Handler HP, Dai Y, Trostle AJ, Wan YW, Liu Z, Sillitoe RV, Orr HT, Zoghbi HY. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron. 2023 02 15; 111(4):481-492.e8. PMID: 36577402; PMCID: PMC9957872.
      Citations: 3     Fields:    Translation:AnimalsCells
    19. Zhou J, Van der Heijden ME, Salazar Leon LE, Lin T, Miterko LN, Kizek DJ, Perez RM, Pave?kovic M, Brown AM, Sillitoe RV. Propranolol Modulates Cerebellar Circuit Activity and Reduces Tremor. Cells. 2022 Dec 01; 11(23). PMID: 36497147; PMCID: PMC9740691.
      Citations:    Fields:    Translation:AnimalsCells
    20. van der Heijden ME, Brown AM, Sillitoe RV. Influence of data sampling methods on the representation of neural spiking activity in?vivo. iScience. 2022 Nov 18; 25(11):105429. PMID: 36388953; PMCID: PMC9641233.
      Citations: 2     
    21. Salazar Leon LE, Sillitoe RV. Potential interactions between cerebellar dysfunction and sleep disturbances in dystonia. Dystonia. 2022 Oct; 1. PMID: 37065094; PMCID: PMC10099477.
      Citations: 1     
    22. Van Der Heijden ME, Gill JS, Rey Hipolito AG, Salazar Leon LE, Sillitoe RV. Quantification of Behavioral Deficits in Developing Mice With Dystonic Behaviors. Dystonia. 2022; 1. PMID: 36960404; PMCID: PMC10032351.
      Citations: 1     
    23. Liang JH, Alevy J, Akhanov V, Seo R, Massey CA, Jiang D, Zhou J, Sillitoe RV, Noebels JL, Samuel MA. Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects. Dis Model Mech. 2022 09 01; 15(9). PMID: 35972048; PMCID: PMC9509889.
      Citations:    
    24. Brown AM, van der Heijden ME, Jinnah HA, Sillitoe RV. Cerebellar Dysfunction as a Source of Dystonic Phenotypes in Mice. Cerebellum. 2023 Aug; 22(4):719-729. PMID: 35821365; PMCID: PMC10307717.
      Citations:    Fields:    
    25. Liu Y, McAfee SS, Van Der Heijden ME, Dhamala M, Sillitoe RV, Heck DH. Causal Evidence for a Role of Cerebellar Lobulus Simplex in Prefrontal-Hippocampal Interaction in Spatial Working Memory Decision-Making. Cerebellum. 2022 Oct; 21(5):762-775. PMID: 35218525; PMCID: PMC10230449.
      Citations: 1     Fields:    
    26. McAfee SS, Liu Y, Sillitoe RV, Heck DH. Cerebellar Coordination of Neuronal Communication in Cerebral Cortex. Front Syst Neurosci. 2021; 15:781527. PMID: 35087384; PMCID: PMC8787113.
      Citations: 1     
    27. van der Heijden ME, Brown AM, Sillitoe RV. Motor control: Internalizing your place in the world. Curr Biol. 2021 12 20; 31(24):R1576-R1578. PMID: 34932966.
      Citations:    Fields:    Translation:Animals
    28. Stevens SR, van der Heijden ME, Ogawa Y, Lin T, Sillitoe RV, Rasband MN. Ankyrin-R Links Kv3.3 to the Spectrin Cytoskeleton and Is Required for Purkinje Neuron Survival. J Neurosci. 2022 01 05; 42(1):2-15. PMID: 34785580; PMCID: PMC8741159.
      Citations: 2     Fields:    Translation:AnimalsCells
    29. van der Heijden ME, Lackey EP, Perez R, I?leyen FS, Brown AM, Donofrio SG, Lin T, Zoghbi HY, Sillitoe RV. Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons. Elife. 2021 09 20; 10. PMID: 34542409; PMCID: PMC8452305.
      Citations: 3     Fields:    Translation:AnimalsCells
    30. Kale RP, Nguyen TTL, Price JB, Yates NJ, Walder K, Berk M, Sillitoe RV, Kouzani AZ, Tye SJ. Mood Regulatory Actions of Active and Sham Nucleus Accumbens Deep Brain Stimulation in Antidepressant Resistant Rats. Front Hum Neurosci. 2021; 15:644921. PMID: 34349629; PMCID: PMC8326323.
      Citations:    
    31. Karamesinis A, Sillitoe RV, Kouzani AZ. Wearable Peripheral Electrical Stimulation Devices for the Reduction of Essential Tremor: A Review. IEEE Access. 2021; 9:80066-80076. PMID: 34178561; PMCID: PMC8224473.
      Citations: 2     
    32. van der Heijden ME, Gill JS, Sillitoe RV. Abnormal Cerebellar Development in Autism Spectrum Disorders. Dev Neurosci. 2021; 43(3-4):181-190. PMID: 33823515; PMCID: PMC8440334.
      Citations: 7     Fields:    Translation:Humans
    33. Miterko LN, Lin T, Zhou J, van der Heijden ME, Beckinghausen J, White JJ, Sillitoe RV. Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia. Nat Commun. 2021 02 26; 12(1):1295. PMID: 33637754; PMCID: PMC7910465.
      Citations: 9     Fields:    Translation:AnimalsCells
    34. Achilly NP, He LJ, Kim OA, Ohmae S, Wojaczynski GJ, Lin T, Sillitoe RV, Medina JF, Zoghbi HY. Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice. Elife. 2021 01 26; 10. PMID: 33494858; PMCID: PMC7837679.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    35. van der Heijden ME, Kizek DJ, Perez R, Ruff EK, Ehrlich ME, Sillitoe RV. Abnormal cerebellar function and tremor in a mouse model for non-manifesting partially penetrant dystonia type 6. J Physiol. 2021 04; 599(7):2037-2054. PMID: 33369735; PMCID: PMC8559601.
      Citations: 5     Fields:    Translation:HumansAnimals
    36. Parastarfeizabadi M, Sillitoe RV, Kouzani AZ. Multi-disease Deep Brain Stimulation. IEEE Access. 2020; 8:216933-216947. PMID: 33381359; PMCID: PMC7771650.
      Citations: 2     
    37. Ito-Ishida A, Baker SA, Sillitoe RV, Sun Y, Zhou J, Ono Y, Iwakiri J, Yuzaki M, Zoghbi HY. MeCP2 Levels Regulate the 3D Structure of Heterochromatic Foci in Mouse Neurons. J Neurosci. 2020 11 04; 40(45):8746-8766. PMID: 33046553; PMCID: PMC7643291.
      Citations: 5     Fields:    Translation:AnimalsCells
    38. Zhou J, Brown AM, Lackey EP, Arancillo M, Lin T, Sillitoe RV. Purkinje cell neurotransmission patterns cerebellar basket cells into zonal modules defined by distinct pinceau sizes. Elife. 2020 09 29; 9. PMID: 32990595; PMCID: PMC7561353.
      Citations: 8     Fields:    Translation:AnimalsCells
    39. van der Heijden ME, Sillitoe RV. Interactions Between Purkinje Cells and Granule Cells Coordinate the Development of Functional Cerebellar Circuits. Neuroscience. 2021 05 10; 462:4-21. PMID: 32554107; PMCID: PMC7736359.
      Citations: 6     Fields:    Translation:HumansCells
    40. Luck B, Engevik MA, Ganesh BP, Lackey EP, Lin T, Balderas M, Major A, Runge J, Luna RA, Sillitoe RV, Versalovic J. Bifidobacteria shape host neural circuits during postnatal development by promoting synapse formation and microglial function. Sci Rep. 2020 05 08; 10(1):7737. PMID: 32385412; PMCID: PMC7210968.
      Citations: 16     Fields:    Translation:AnimalsCells
    41. Liu Y, Qi S, Thomas F, Correia BL, Taylor AP, Sillitoe RV, Heck DH. Loss of cerebellar function selectively affects intrinsic rhythmicity of eupneic breathing. Biol Open. 2020 04 13; 9(4). PMID: 32086251; PMCID: PMC7197709.
      Citations: 3     Fields:    Translation:Animals
    42. Brown AM, White JJ, van der Heijden ME, Zhou J, Lin T, Sillitoe RV. Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation. Elife. 2020 03 17; 9. PMID: 32180549; PMCID: PMC7077982.
      Citations: 14     Fields:    Translation:AnimalsCells
    43. Lungu C, Ozelius L, Standaert D, Hallett M, Sieber BA, Swanson-Fisher C, Berman BD, Calakos N, Moore JC, Perlmutter JS, Pirio Richardson SE, Saunders-Pullman R, Scheinfeldt L, Sharma N, Sillitoe R, Simonyan K, Starr PA, Taylor A, Vitek J, participants and organizers of the NINDS Workshop on Research Priorities in Dystonia. Defining research priorities in dystonia. Neurology. 2020 03 24; 94(12):526-537. PMID: 32098856; PMCID: PMC7274927.
      Citations: 8     Fields:    Translation:HumansAnimals
    44. Lackey EP, Sillitoe RV. Eph/ephrin Function Contributes to the Patterning of Spinocerebellar Mossy Fibers Into Parasagittal Zones. Front Syst Neurosci. 2020; 14:7. PMID: 32116578; PMCID: PMC7033604.
      Citations: 4     
    45. Stay TL, Miterko LN, Arancillo M, Lin T, Sillitoe RV. In vivo cerebellar circuit function is disrupted in an mdx mouse model of Duchenne muscular dystrophy. Dis Model Mech. 2019 12 09; 13(2). PMID: 31704708; PMCID: PMC6906634.
      Citations: 5     Fields:    Translation:AnimalsCells
    46. Kuo SH, Louis ED, Faust PL, Handforth A, Chang SY, Avlar B, Lang EJ, Pan MK, Miterko LN, Brown AM, Sillitoe RV, Anderson CJ, Pulst SM, Gallagher MJ, Lyman KA, Chetkovich DM, Clark LN, Tio M, Tan EK, Elble RJ. Current Opinions and Consensus for Studying Tremor in Animal Models. Cerebellum. 2019 Dec; 18(6):1036-1063. PMID: 31124049; PMCID: PMC6872927.
      Citations: 10     Fields:    Translation:Animals
    47. Miterko LN, Baker KB, Beckinghausen J, Bradnam LV, Cheng MY, Cooperrider J, DeLong MR, Gornati SV, Hallett M, Heck DH, Hoebeek FE, Kouzani AZ, Kuo SH, Louis ED, Machado A, Manto M, McCambridge AB, Nitsche MA, Taib NOB, Popa T, Tanaka M, Timmann D, Steinberg GK, Wang EH, Wichmann T, Xie T, Sillitoe RV. Consensus Paper: Experimental Neurostimulation of the Cerebellum. Cerebellum. 2019 Dec; 18(6):1064-1097. PMID: 31165428; PMCID: PMC6867990.
      Citations: 49     Fields:    Translation:HumansAnimals
    48. Gill JS, Sillitoe RV. Functional Outcomes of Cerebellar Malformations. Front Cell Neurosci. 2019; 13:441. PMID: 31636540; PMCID: PMC6787289.
      Citations: 9     
    49. Meng X, McGraw CM, Wang W, Jing J, Yeh SY, Wang L, Lopez J, Brown AM, Lin T, Chen W, Xue M, Sillitoe RV, Jiang X, Zoghbi HY. Neurexophilin4 is a selectively expressed a-neurexin ligand that modulates specific cerebellar synapses and motor functions. Elife. 2019 09 16; 8. PMID: 31524598; PMCID: PMC6763262.
      Citations: 6     Fields:    Translation:AnimalsCells
    50. McAfee SS, Liu Y, Sillitoe RV, Heck DH. Cerebellar Lobulus Simplex and Crus I Differentially Represent Phase and Phase Difference of Prefrontal Cortical and Hippocampal Oscillations. Cell Rep. 2019 05 21; 27(8):2328-2334.e3. PMID: 31116979; PMCID: PMC6538275.
      Citations: 26     Fields:    
    51. Sathyanesan A, Zhou J, Scafidi J, Heck DH, Sillitoe RV, Gallo V. Emerging connections between cerebellar development, behaviour and complex brain disorders. Nat Rev Neurosci. 2019 05; 20(5):298-313. PMID: 30923348; PMCID: PMC7236620.
      Citations: 55     Fields:    Translation:HumansAnimals
    52. Miterko LN, White JJ, Lin T, Brown AM, O'Donovan KJ, Sillitoe RV. Persistent motor dysfunction despite homeostatic rescue of cerebellar morphogenesis in the Car8 waddles mutant mouse. Neural Dev. 2019 03 12; 14(1):6. PMID: 30867000; PMCID: PMC6417138.
      Citations: 5     Fields:    Translation:AnimalsCells
    53. Brown AM, Arancillo M, Lin T, Catt DR, Zhou J, Lackey EP, Stay TL, Zuo Z, White JJ, Sillitoe RV. Molecular layer interneurons shape the spike activity of cerebellar Purkinje cells. Sci Rep. 2019 02 11; 9(1):1742. PMID: 30742002; PMCID: PMC6370775.
      Citations: 32     Fields:    Translation:AnimalsCells
    54. Stay TL, Laurens J, Sillitoe RV, Angelaki DE. Genetically eliminating Purkinje neuron GABAergic neurotransmission increases their response gain to vestibular motion. Proc Natl Acad Sci U S A. 2019 02 19; 116(8):3245-3250. PMID: 30723151; PMCID: PMC6386715.
      Citations: 4     Fields:    Translation:AnimalsCells
    55. Parastarfeizabadi M, Kouzani AZ, Beckinghausen J, Lin T, Sillitoe RV. A Programmable Multi-biomarker Neural Sensor for Closed-loop DBS. IEEE Access. 2018; 7:230-244. PMID: 30976472; PMCID: PMC6453143.
      Citations: 1     
    56. Miterko LN, Lackey EP, Heck DH, Sillitoe RV. Shaping Diversity Into the Brain's Form and Function. Front Neural Circuits. 2018; 12:83. PMID: 30364100; PMCID: PMC6191489.
      Citations: 7     Fields:    Translation:HumansAnimals
    57. Apps R, Hawkes R, Aoki S, Bengtsson F, Brown AM, Chen G, Ebner TJ, Lackey EP, Lawrenson C, Lumb B, Schonewille M, Sillitoe RV, Sugihara I, Voogd J, Wylie DR, Ruigrok TJH, Isope P, J?rntell H, Spaeth L, Valera A. Correction to: Cerebellar Modules and Their Role as Operational Cerebellar Processing Units: A Consensus paper. Cerebellum. 2018 10; 17(5):683-684. PMID: 29931663; PMCID: PMC6828140.
      Citations: 2     Fields:    
    58. Apps R, Hawkes R, Aoki S, Bengtsson F, Brown AM, Chen G, Ebner TJ, Lackey EP, Lawrenson C, Lumb B, Schonewille M, Sillitoe RV, Sugihara I, Voogd J, Wylie DR, Ruigrok TJH, Isope P, J?rntell H, Spaeth L, Valera A. Cerebellar Modules and Their Role as Operational Cerebellar Processing Units: A Consensus paper [corrected]. Cerebellum. 2018 10; 17(5):654-682. PMID: 29876802; PMCID: PMC6132822.
      Citations: 55     Fields:    Translation:HumansAnimals
    59. Reeber SL, Arancillo M, Sillitoe RV. Bergmann Glia are Patterned into Topographic Molecular Zones in the Developing and Adult Mouse Cerebellum. Cerebellum. 2018 Aug; 17(4):392-403. PMID: 24906823; PMCID: PMC4291305.
      Citations: 12     Fields:    Translation:AnimalsCells
    60. Lackey EP, Heck DH, Sillitoe RV. Recent advances in understanding the mechanisms of cerebellar granule cell development and function and their contribution to behavior. F1000Res. 2018; 7. PMID: 30109024; PMCID: PMC6069759.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    61. Dhar SS, Zhao D, Lin T, Gu B, Pal K, Wu SJ, Alam H, Lv J, Yun K, Gopalakrishnan V, Flores ER, Northcott PA, Rajaram V, Li W, Shilatifard A, Sillitoe RV, Chen K, Lee MG. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes. Mol Cell. 2018 06 07; 70(5):825-841.e6. PMID: 29861161; PMCID: PMC6528658.
      Citations: 55     Fields:    Translation:AnimalsCells
    62. Beckinghausen J, Sillitoe RV. Insights into cerebellar development and connectivity. Neurosci Lett. 2019 01 01; 688:2-13. PMID: 29746896; PMCID: PMC6222004.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    63. Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajic A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism. Neuron. 2018 03 21; 97(6):1235-1243.e5. PMID: 29526553; PMCID: PMC6422678.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    64. Miterko LN, Sillitoe RV. Climbing Fiber Development Is Impaired in Postnatal Car8 wdl Mice. Cerebellum. 2018 Feb; 17(1):56-61. PMID: 28940157; PMCID: PMC6053913.
      Citations: 3     Fields:    Translation:AnimalsCells
    65. Levy SL, White JJ, Lackey EP, Schwartz L, Sillitoe RV. WGA-Alexa Conjugates for Axonal Tracing. Curr Protoc Neurosci. 2017 Apr 10; 79:1.28.1-1.28.24. PMID: 28398642; PMCID: PMC5830103.
      Citations: 6     Fields:    Translation:AnimalsCells
    66. White JJ, Sillitoe RV. Genetic silencing of olivocerebellar synapses causes dystonia-like behaviour in mice. Nat Commun. 2017 04 04; 8:14912. PMID: 28374839; PMCID: PMC5382291.
      Citations: 51     Fields:    Translation:AnimalsCells
    67. Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, Finnell RH, Lei Y, Zurita-Jimenez ME, Ahimaz P, Anyane-Yeboa K, Lehalle D, Jean-Marcais N, Mosca-Boidron AL, Thevenon J, Cousin MA, Bro DE, Lanpher BC, Klee EW, Alexander N, Bainbridge MN, Orr HT, Sillitoe RV, Ljungberg MC, Liu Z, Schaaf CP, Zoghbi HY, Van Maldergem L. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr; 49(4):527-536. PMID: 28288114; PMCID: PMC5374026.
      Citations: 49     Fields:    Translation:HumansAnimals
    68. Miterko LN, Sillitoe RV. The pledge, the turn, and the prestige of transient cerebellar alterations in SCA6. J Physiol. 2017 02 01; 595(3):607-608. PMID: 28145007; PMCID: PMC5285714.
      Citations:    Fields:    Translation:Animals
    69. Tan Q, Yalamanchili HK, Park J, De Maio A, Lu HC, Wan YW, White JJ, Bondar VV, Sayegh LS, Liu X, Gao Y, Sillitoe RV, Orr HT, Liu Z, Zoghbi HY. Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models. Hum Mol Genet. 2016 12 01; 25(23):5083-5093. PMID: 28007900; PMCID: PMC5968355.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    70. Leto K, Arancillo M, Becker EB, Buffo A, Chiang C, Ding B, Dobyns WB, Haldipur P, Hatten ME, Hoshino M, Joyner AL, Kano M, Kilpatrick DL, Koibuchi N, Marino S, Martinez S, Millen KJ, Millner TO, Miyata T, Parmigiani E, Sillitoe RV, Uesaka N, Wefers A, Wingate RJ, Hawkes R, Dusart I, Schilling K, Sekerkov? G, Sotelo C. Consensus Paper: Cerebellar Development. Cerebellum. 2016 12; 15(6):789-828. PMID: 26439486; PMCID: PMC4846577.
      Citations: 133     Fields:    Translation:HumansAnimalsCells
    71. Hopfner F, Haubenberger D, Galpern WR, Gwinn K, Van't Veer A, White S, Bhatia K, Adler CH, Eidelberg D, Ondo W, Stebbins GT, Tanner CM, Helmich RC, Lenz FA, Sillitoe RV, Vaillancourt D, Vitek JL, Louis ED, Shill HA, Frosch MP, Foroud T, Singleton A, Testa CM, Hallett M, Elble R, Kuhlenb?umer G, Deuschl G. Knowledge gaps and research recommendations for essential tremor. Parkinsonism Relat Disord. 2016 12; 33:27-35. PMID: 27769649; PMCID: PMC5271603.
      Citations: 20     Fields:    Translation:HumansAnimals
    72. Sillitoe RV. Mossy Fibers Terminate Directly Within Purkinje Cell Zones During Mouse Development. Cerebellum. 2016 Feb; 15(1):14-17. PMID: 26255945; PMCID: PMC4729619.
      Citations: 13     Fields:    Translation:AnimalsCells
    73. White JJ, Lin T, Brown AM, Arancillo M, Lackey EP, Stay TL, Sillitoe RV. An optimized surgical approach for obtaining stable extracellular single-unit recordings from the cerebellum of head-fixed behaving mice. J Neurosci Methods. 2016 Mar 15; 262:21-31. PMID: 26777474; PMCID: PMC4778558.
      Citations: 14     Fields:    Translation:AnimalsCells
    74. White JJ, Arancillo M, King A, Lin T, Miterko LN, Gebre SA, Sillitoe RV. Pathogenesis of severe ataxia and tremor without the typical signs of neurodegeneration. Neurobiol Dis. 2016 Feb; 86:86-98. PMID: 26586559; PMCID: PMC4778569.
      Citations: 20     Fields:    Translation:AnimalsCells
    75. Lee SK, Sillitoe RV, Silva C, Martina M, Sekerkova G. a-Synuclein expression in the mouse cerebellum is restricted to VGluT1 excitatory terminals and is enriched in unipolar brush cells. Cerebellum. 2015 Oct; 14(5):516-27. PMID: 25917213; PMCID: PMC4668925.
      Citations: 11     Fields:    Translation:AnimalsCells
    76. Tian X, Gala U, Zhang Y, Shang W, Nagarkar Jaiswal S, di Ronza A, Jaiswal M, Yamamoto S, Sandoval H, Duraine L, Sardiello M, Sillitoe RV, Venkatachalam K, Fan H, Bellen HJ, Tong C. A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis. PLoS Biol. 2015 Mar; 13(3):e1002103. PMID: 25811491; PMCID: PMC4374850.
      Citations: 48     Fields:    Translation:AnimalsCells
    77. Gennarino VA, Singh RK, White JJ, De Maio A, Han K, Kim JY, Jafar-Nejad P, di Ronza A, Kang H, Sayegh LS, Cooper TA, Sillitoe RV, Zoghbi HY, Orr HT. Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels. Cell. 2015 Mar 12; 160(6):1087-98. PMID: 25768905; PMCID: PMC4383046.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    78. Cerminara NL, Lang EJ, Sillitoe RV, Apps R. Redefining the cerebellar cortex as an assembly of non-uniform Purkinje cell microcircuits. Nat Rev Neurosci. 2015 Feb; 16(2):79-93. PMID: 25601779; PMCID: PMC4476393.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    79. Arancillo M, White JJ, Lin T, Stay TL, Sillitoe RV. In vivo analysis of Purkinje cell firing properties during postnatal mouse development. J Neurophysiol. 2015 Jan 15; 113(2):578-91. PMID: 25355961; PMCID: PMC4297795.
      Citations: 40     Fields:    Translation:AnimalsCells
    80. Mulherkar S, Uddin MD, Couvillon AD, Sillitoe RV, Tolias KF. The small GTPases RhoA and Rac1 regulate cerebellar development by controlling cell morphogenesis, migration and foliation. Dev Biol. 2014 Oct 01; 394(1):39-53. PMID: 25128586; PMCID: PMC4163514.
      Citations: 13     Fields:    Translation:AnimalsCells
    81. White JJ, Arancillo M, Stay TL, George-Jones NA, Levy SL, Heck DH, Sillitoe RV. Cerebellar zonal patterning relies on Purkinje cell neurotransmission. J Neurosci. 2014 Jun 11; 34(24):8231-45. PMID: 24920627; PMCID: PMC4051975.
      Citations: 45     Fields:    Translation:AnimalsCells
    82. Reeber SL, Otis TS, Sillitoe RV. New roles for the cerebellum in health and disease. Front Syst Neurosci. 2013; 7:83. PMID: 24294192; PMCID: PMC3827539.
      Citations: 83     
    83. Reeber SL, Loeschel CA, Franklin A, Sillitoe RV. Establishment of topographic circuit zones in the cerebellum of scrambler mutant mice. Front Neural Circuits. 2013; 7:122. PMID: 23885237; PMCID: PMC3717479.
      Citations: 11     Fields:    Translation:AnimalsCells
    84. White JJ, Sillitoe RV. Postnatal development of cerebellar zones revealed by neurofilament heavy chain protein expression. Front Neuroanat. 2013; 7:9. PMID: 23675325; PMCID: PMC3648691.
      Citations: 20     
    85. Reeber SL, White JJ, George-Jones NA, Sillitoe RV. Architecture and development of olivocerebellar circuit topography. Front Neural Circuits. 2012; 6:115. PMID: 23293588; PMCID: PMC3534185.
      Citations: 14     Fields:    
    86. Sillitoe RV. An introduction to journal club in The Cerebellum. Cerebellum. 2012 Dec; 11(4):828. PMID: 23086707.
      Citations: 1     Fields:    
    87. Sillitoe RV, George-Jones NA, Millen KJ, Hawkes R. Purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher. Brain Struct Funct. 2014 Jan; 219(1):35-47. PMID: 23160833; PMCID: PMC4140632.
      Citations: 3     Fields:    Translation:AnimalsCells
    88. Sakai N, Insolera R, Sillitoe RV, Shi SH, Kaprielian Z. Axon sorting within the spinal cord marginal zone via Robo-mediated inhibition of N-cadherin controls spinocerebellar tract formation. J Neurosci. 2012 Oct 31; 32(44):15377-87. PMID: 23115176; PMCID: PMC3511830.
      Citations: 21     Fields:    Translation:AnimalsCells
    89. White JJ, Sillitoe RV. Development of the cerebellum: from gene expression patterns to circuit maps. Wiley Interdiscip Rev Dev Biol. 2013 Jan-Feb; 2(1):149-64. PMID: 23799634.
      Citations: 63     Fields:    Translation:HumansAnimals
    90. White JJ, Reeber SL, Hawkes R, Sillitoe RV. Wholemount immunohistochemistry for revealing complex brain topography. J Vis Exp. 2012 Apr 05; (62):e4042. PMID: 22508094; PMCID: PMC3466652.
      Citations: 8     Fields:    Translation:Animals
    91. Reeber SL, Gebre SA, Filatova N, Sillitoe RV. Revealing neural circuit topography in multi-color. J Vis Exp. 2011 Nov 14; (57). PMID: 22105327; PMCID: PMC3308607.
      Citations: 4     Fields:    Translation:AnimalsCells
    92. Dobrenis K, Sillitoe RV, Gulinello M, Ali NF, Davidson C, Micsenyi MC, Stephney G, Ellevog L, Klungland A, Walkley SU, Str?mme P. X-linked Angelman-like syndrome caused by Slc9a6 knockout in mice exhibits evidence of endosomal-lysosomal dysfunction. Brain. 2011 Nov; 134(Pt 11):3369-83. PMID: 21964919; PMCID: PMC3212719.
      Citations: 41     Fields:    Translation:AnimalsCells
    93. Demilly A, Reeber SL, Gebre SA, Sillitoe RV. Neurofilament heavy chain expression reveals a unique parasagittal stripe topography in the mouse cerebellum. Cerebellum. 2011 Sep; 10(3):409-21. PMID: 20127431.
      Citations: 12     Fields:    Translation:Animals
    94. Oberdick J, Sillitoe RV. Cerebellar zones: history, development, and function. Cerebellum. 2011 Sep; 10(3):301-6. PMID: 21822545.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    95. Gebre SA, Reeber SL, Sillitoe RV. Parasagittal compartmentation of cerebellar mossy fibers as revealed by the patterned expression of vesicular glutamate transporters VGLUT1 and VGLUT2. Brain Struct Funct. 2012 Apr; 217(2):165-80. PMID: 21814870.
      Citations: 33     Fields:    Translation:AnimalsCells
    96. Reeber SL, Sillitoe RV. Patterned expression of a cocaine- and amphetamine-regulated transcript peptide reveals complex circuit topography in the rodent cerebellar cortex. J Comp Neurol. 2011 Jun 15; 519(9):1781-96. PMID: 21452228.
      Citations: 20     Fields:    Translation:AnimalsCells
    97. Reeber SL, Gebre SA, Sillitoe RV. Fluorescence mapping of afferent topography in three dimensions. Brain Struct Funct. 2011 Sep; 216(3):159-69. PMID: 21387082.
      Citations: 15     Fields:    Translation:Animals
    98. Sillitoe RV, Vogel MW, Joyner AL. Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map. J Neurosci. 2010 Jul 28; 30(30):10015-24. PMID: 20668186; PMCID: PMC2921890.
      Citations: 66     Fields:    Translation:AnimalsCells
    99. Chung SH, Sillitoe RV, Croci L, Badaloni A, Consalez G, Hawkes R. Purkinje cell phenotype restricts the distribution of unipolar brush cells. Neuroscience. 2009 Dec 29; 164(4):1496-508. PMID: 19800947.
      Citations: 15     Fields:    Translation:AnimalsCells
    100. Sillitoe RV, Gopal N, Joyner AL. Embryonic origins of ZebrinII parasagittal stripes and establishment of topographic Purkinje cell projections. Neuroscience. 2009 Sep 01; 162(3):574-88. PMID: 19150487; PMCID: PMC2716412.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    101. Sillitoe RV, Stephen D, Lao Z, Joyner AL. Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum. J Neurosci. 2008 Nov 19; 28(47):12150-62. PMID: 19020009; PMCID: PMC2864318.
      Citations: 45     Fields:    Translation:AnimalsCells
    102. Sillitoe RV, Chung SH, Fritschy JM, Hoy M, Hawkes R. Golgi cell dendrites are restricted by Purkinje cell stripe boundaries in the adult mouse cerebellar cortex. J Neurosci. 2008 Mar 12; 28(11):2820-6. PMID: 18337412; PMCID: PMC6670690.
      Citations: 35     Fields:    Translation:AnimalsCells
    103. Sillitoe RV, Vogel MW. Desire, disease, and the origins of the dopaminergic system. Schizophr Bull. 2008 Mar; 34(2):212-9. PMID: 18283047; PMCID: PMC2632401.
      Citations: 13     Fields:    Translation:HumansCells
    104. Esapa CT, Waite A, Locke M, Benson MA, Kraus M, McIlhinney RA, Sillitoe RV, Beesley PW, Blake DJ. SGCE missense mutations that cause myoclonus-dystonia syndrome impair epsilon-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA. Hum Mol Genet. 2007 Feb 01; 16(3):327-42. PMID: 17200151.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    105. Sillitoe RV, Joyner AL. Morphology, molecular codes, and circuitry produce the three-dimensional complexity of the cerebellum. Annu Rev Cell Dev Biol. 2007; 23:549-77. PMID: 17506688.
      Citations: 198     Fields:    Translation:HumansAnimalsCells
    106. Sillitoe RV, Marzban H, Larouche M, Zahedi S, Affanni J, Hawkes R. Conservation of the architecture of the anterior lobe vermis of the cerebellum across mammalian species. Prog Brain Res. 2005; 148:283-97. PMID: 15661197.
      Citations: 41     Fields:    Translation:Animals
    107. Benson MA, Sillitoe RV, Blake DJ. Schizophrenia genetics: dysbindin under the microscope. Trends Neurosci. 2004 Sep; 27(9):516-9. PMID: 15331232.
      Citations: 9     Fields:    Translation:HumansAnimals
    108. Sillitoe RV, Malz CR, Rockland K, Hawkes R. Antigenic compartmentation of the primate and tree shrew cerebellum: a common topography of zebrin II in Macaca mulatta and Tupaia belangeri. J Anat. 2004 Apr; 204(4):257-69. PMID: 15061752; PMCID: PMC1571299.
      Citations: 10     Fields:    Translation:AnimalsCells
    109. Marzban H, Sillitoe RV, Hoy M, Chung SH, Rafuse VF, Hawkes R. Abnormal HNK-1 expression in the cerebellum of an N-CAM null mouse. J Neurocytol. 2004 Jan; 33(1):117-30. PMID: 15173636.
      Citations: 20     Fields:    Translation:Animals
    110. Sillitoe RV, Hawkes R, K?nzle H. Zebrin II compartmentation of the cerebellum in a basal insectivore, the Madagascan hedgehog tenrec Echinops telfairi. J Anat. 2003 Sep; 203(3):283-96. PMID: 14529046; PMCID: PMC1571161.
      Citations: 11     Fields:    Translation:AnimalsCells
    111. Sillitoe RV, Benson MA, Blake DJ, Hawkes R. Abnormal dysbindin expression in cerebellar mossy fiber synapses in the mdx mouse model of Duchenne muscular dystrophy. J Neurosci. 2003 Jul 23; 23(16):6576-85. PMID: 12878699; PMCID: PMC6740624.
      Citations: 36     Fields:    Translation:AnimalsCells
    112. Sillitoe RV, Hulliger M, Dyck R, Hawkes R. Antigenic compartmentation of the cat cerebellar cortex. Brain Res. 2003 Jul 04; 977(1):1-15. PMID: 12788507.
      Citations: 10     Fields:    Translation:AnimalsCells
    113. Larouche M, Diep C, Sillitoe RV, Hawkes R. Topographical anatomy of the cerebellum in the guinea pig, Cavia porcellus. Brain Res. 2003 Mar 07; 965(1-2):159-69. PMID: 12591133.
      Citations: 6     Fields:    Translation:Animals
    114. Sarna JR, Larouche M, Marzban H, Sillitoe RV, Rancourt DE, Hawkes R. Patterned Purkinje cell degeneration in mouse models of Niemann-Pick type C disease. J Comp Neurol. 2003 Feb 10; 456(3):279-91. PMID: 12528192.
      Citations: 116     Fields:    Translation:AnimalsCells
    115. Jeong YG, Rosales JL, Marzban H, Sillitoe RV, Park DG, Hawkes R, Lee KY. The cyclin-dependent kinase 5 activator, p39, is expressed in stripes in the mouse cerebellum. Neuroscience. 2003; 118(2):323-34. PMID: 12699769.
      Citations: 6     Fields:    Translation:AnimalsCells
    116. Sillitoe RV, Hawkes R. Whole-mount immunohistochemistry: a high-throughput screen for patterning defects in the mouse cerebellum. J Histochem Cytochem. 2002 Feb; 50(2):235-44. PMID: 11799142.
      Citations: 66     Fields:    Translation:AnimalsCells
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