TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1100 BATES
Houston, TX 77030
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    1-17-JDF-037     (Stephanie Sisley)Jan 1, 2017 - Jun 30, 2021
    American Diabetes Association
    Brain vitamin D receptor mediation of glucose homeostasis
    Role Description: The goal of this study is to determine the role of vitamin D and it's receptor within the paraventricular hypothalamus of the brain on blood sugar control.
    Role: Principle Investigator

    K08DK106447     (SISLEY, STEPHANIE RENEE)Sep 1, 2016 - Dec 31, 2016
    Mechanisms of CNS Vitamin D Receptor in Weight Regulation
    Role: Principal Investigator

    F32DK091077     (SISLEY, STEPHANIE RENEE)Jul 1, 2011 - Jul 31, 2013
    CNS NFkappaB Regulation of Glucose Homeostasis
    Role: Principal Investigator

         (Dennis Bier)
    United States Department of Agriculture
    Research and research education to improve the nutrition of infants, children, adolescents and pregnant and lactating women
    Role Description: he mission of the Children's Nutrition Research Center (CNRC) is to conduct research that will lead to a definition of the nutritional requirements needed to ensure health in children from conception through adolescence, and in pregnant and lactating women. To accomplish this mission, the CNRC maintains these research areas: a. Nutritional Metabolism in Mothers, Infants and Children b. Pediatric Clinical Nutrition c. Childhood Obesity Prevention d. Developmental Determinants of Obesity in Infants and Children e. Molecular, Cellular and Regulatory aspects of Nutrition during Development This research is to be accomplished over a multi-year period as resources are available via a specific cooperative agreement.
    Role: Co-investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. DeMello AS, Acorda DE, Thompson D, Allen DL, Aman R, Brandt ML, Sisley S. Growing Up After Adolescent Bariatric Surgery. Clin Nurs Res. 2023 01; 32(1):115-125. PMID: 36169264.
    2. Bryant K, Sandhu J, Nguyen J, Asonye E, Thompson D, Sisley S. Isolation in a Sea of "Experts": Identifying the Parental Struggles Caring for Children with Early-Onset Obesity. Child Obes. 2022 Sep 16. PMID: 36112365.
    3. Isart FA, Isart-Infante FJ, Heidel ER, Sisley S. Acanthosis Nigricans Is a Strong Predictor of Low Blood Calcidiol Levels in Children and Adolescents. Metab Syndr Relat Disord. 2022 11; 20(9):509-516. PMID: 35834574.
      Citations:    Fields:    
    4. Gandhi AA, Wilson TA, Sisley S, Elsea SH, Foster RH. Relationships between food-related behaviors, obesity, and medication use in individuals with Smith-Magenis syndrome. Res Dev Disabil. 2022 Aug; 127:104257. PMID: 35597045.
      Citations:    Fields:    Translation:Humans
    5. Beck J, da Silva Teixeira S, Harrison K, Phillips G, He Y, Sisley S. Paraventricular Vitamin D Receptors Are Required for Glucose Tolerance in Males but Not Females. Front Endocrinol (Lausanne). 2022; 13:869678. PMID: 35620386; PMCID: PMC9128386.
      Citations:    Fields:    Translation:Animals
    6. Costello E, Rock S, Stratakis N, Eckel SP, Walker DI, Valvi D, Cserbik D, Jenkins T, Xanthakos SA, Kohli R, Sisley S, Vasiliou V, La Merrill MA, Rosen H, Conti DV, McConnell R, Chatzi L. Exposure to per- and Polyfluoroalkyl Substances and Markers of Liver Injury: A Systematic Review and Meta-Analysis. Environ Health Perspect. 2022 04; 130(4):46001. PMID: 35475652; PMCID: PMC9044977.
      Citations: 2     Fields:    Translation:Humans
    7. Puri K, Adachi I, Bocchini CE, Spinner JA, Denfield SW, Sisley S, Elias BA, Jimenez-Gomez A, Price JF, Dreyer WJ, Choudhry S, Tunuguntla HP. Trends in Body Mass Index and Association With Outcomes in Pediatric Patients on Continuous Flow Ventricular Assist Device Support. ASAIO J. 2022 09 01; 68(9):1182-1190. PMID: 34967787.
      Citations:    Fields:    
    8. Astudillo M, Tosur M, Castillo B, Rafaey A, Siller AF, Nieto J, Sisley S, McKay S, Nella AA, Balasubramanyam A, Bacha F, Redondo MJ. Type 2 diabetes in prepubertal children. Pediatr Diabetes. 2021 11; 22(7):946-950. PMID: 34363430.
      Citations: 5     Fields:    Translation:Humans
    9. Al-Gadi I, Sisley S. Case-Based Curriculum for Pediatric Residents in Diabetes Fundamentals. MedEdPORTAL. 2021 05 27; 17:11157. PMID: 34124348; PMCID: PMC8155076.
      Citations:    Fields:    Translation:Humans
    10. Liu H, He Y, Beck J, da Silva Teixeira S, Harrison K, Xu Y, Sisley S. Defining vitamin D receptor expression in the brain using a novel VDRCre mouse. J Comp Neurol. 2021 06; 529(9):2362-2375. PMID: 33368246; PMCID: PMC8053677.
      Citations: 5     Fields:    Translation:Animals
    11. Redondo MJ, Siller AF, Gu X, Tosur M, Bondy M, Devaraj S, Sisley S. Sex differences in circulating leptin as a marker of adiposity in obese or overweight adolescents with type 1 diabetes. BMJ Open Diabetes Res Care. 2020 10; 8(1). PMID: 33087341; PMCID: PMC7580039.
      Citations:    Translation:Humans
    12. Athanassaki I, Lyons S, DeSalvo D, Hendrix K, Ebenezer S, McCann-Crosby B, Redondo M, Chen MJ, Uysal S, Sisley S. Diabetes Curriculum for Pediatric Endocrine Fellowship Utilizing Modified Team-Based Learning. MedEdPORTAL. 2020 08 13; 16:10948. PMID: 32821810; PMCID: PMC7431187.
      Citations: 2     Fields:    Translation:Humans
    13. Zachary M, Sisley S. The Pediatric Obesity Encounter: Literature and Resources to Help with 4 Common Issues. Curr Nutr Rep. 2020 06; 9(2):94-100. PMID: 32350815.
      Citations: 1     Fields:    Translation:Humans
    14. da Silva Teixeira S, Harrison K, Uzodike M, Rajapakshe K, Coarfa C, He Y, Xu Y, Sisley S. Vitamin D actions in neurons require the PI3K pathway for both enhancing insulin signaling and rapid depolarizing effects. J Steroid Biochem Mol Biol. 2020 06; 200:105690. PMID: 32408067; PMCID: PMC7397709.
      Citations: 6     Fields:    Translation:AnimalsCells
    15. Horne VE, Bielamowicz K, Nguyen J, Hilsenbeck S, Lindsay H, Sonabend R, Wood AC, Okcu F, Sisley S. Methylphenidate improves weight control in childhood brain tumor survivors with hypothalamic obesity. Pediatr Blood Cancer. 2020 07; 67(7):e28379. PMID: 32383818.
      Citations: 2     Fields:    Translation:Humans
    16. Harrison K, Sisley S. Vitamin D and the paraventricular nucleus: Relevance for type 2 diabetes. J Steroid Biochem Mol Biol. 2018 03; 177:125-128. PMID: 28993246.
      Citations: 1     Fields:    Translation:HumansAnimals
    17. Sisley SR, Arble DM, He Y, Xu Y, Gardner D, Moore DD, Seeley RJ, Sandoval DA, Chambers AP, Gutierrez-Aguilar R. Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight. Diabetes. 2016 09; 65(9):2732-41. PMID: 27217488; PMCID: PMC5001188.
      Citations: 17     Fields:    Translation:AnimalsCells
    18. Gao H, Sisley S, Yallampalli C. Blunted hypothalamic ghrelin signaling reduces diet intake in rats fed a low-protein diet in late pregnancy. Physiol Rep. 2015 Dec; 3(12). PMID: 26660550; PMCID: PMC4760445.
      Citations: 2     Fields:    
    19. Sandoval D, Sisley SR. Brain GLP-1 and insulin sensitivity. Mol Cell Endocrinol. 2015 Dec 15; 418 Pt 1:27-32. PMID: 25724479; PMCID: PMC4547906.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    20. Sisley S, Smith K, Sandoval DA, Seeley RJ. Differences in acute anorectic effects of long-acting GLP-1 receptor agonists in rats. Peptides. 2014 Aug; 58:1-6. PMID: 24879927; PMCID: PMC4113007.
      Citations: 11     Fields:    Translation:Animals
    21. Sisley S, Gutierrez-Aguilar R, Scott M, D'Alessio DA, Sandoval DA, Seeley RJ. Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect. J Clin Invest. 2014 Jun; 124(6):2456-63. PMID: 24762441; PMCID: PMC4038572.
      Citations: 136     Fields:    Translation:Animals
    22. Chambers AP, Smith EP, Begg DP, Grayson BE, Sisley S, Greer T, Sorrell J, Lemmen L, LaSance K, Woods SC, Seeley RJ, D'Alessio DA, Sandoval DA. Regulation of gastric emptying rate and its role in nutrient-induced GLP-1 secretion in rats after vertical sleeve gastrectomy. Am J Physiol Endocrinol Metab. 2014 Feb 15; 306(4):E424-32. PMID: 24368666; PMCID: PMC3923088.
      Citations: 60     Fields:    Translation:Animals
    23. Heppner KM, Piechowski CL, Ottaway N, Sisley S, Smiley DL, Habegger KM, Pfluger PT, Dimarchi R, Biebermann H, Sandoval DA, Perez-Tilve D, M?ller A, Tsch?p MH. Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors. Diabetes. 2014 Jan; 63(1):122-31. PMID: 24062249; PMCID: PMC3868046.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    24. Sisley S, Backeljauw P. Reply: To PMID 23706358. J Pediatr. 2013 Nov; 163(5):1535. PMID: 24011758.
      Citations:    Fields:    Translation:Humans
    25. Sisley S, Sandoval D, Herbach N, Zengin A, Fischereder M, Menhofer D, Stoehr BJ, Stemmer K, Seeley RJ, Bidlingmaier M, Bielohuby M, Wanke R, Tsch?p MH. Impaired glucose tolerance in rats fed low-carbohydrate, high-fat diets. Am J Physiol Endocrinol Metab. 2013 Nov 01; 305(9):E1059-70. PMID: 23982154.
      Citations: 33     Fields:    Translation:AnimalsCells
    26. Sisley S, Trujillo MV, Khoury J, Backeljauw P. Low incidence of pathology detection and high cost of screening in the evaluation of asymptomatic short children. J Pediatr. 2013 Oct; 163(4):1045-51. PMID: 23706358; PMCID: PMC3786014.
      Citations: 24     Fields:    Translation:Humans
    27. Sandoval D, Barrera JG, Stefater MA, Sisley S, Woods SC, D'Alessio DD, Seeley RJ. The anorectic effect of GLP-1 in rats is nutrient dependent. PLoS One. 2012; 7(12):e51870. PMID: 23284795; PMCID: PMC3524167.
      Citations: 16     Fields:    Translation:Animals
    28. Sisley S, Sandoval D. Hypothalamic control of energy and glucose metabolism. Rev Endocr Metab Disord. 2011 Sep; 12(3):219-33. PMID: 21695389.
      Citations: 18     Fields:    Translation:Humans
    29. Chambers AP, Jessen L, Ryan KK, Sisley S, Stefater MA, Gaitonde SG, Sorrell JE, Toure M, Berger J, D'Alessio DA, Woods SC, Seeley RJ, Sandoval DA, Wilson-P?rez HE. Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. Gastroenterology. 2011 Sep; 141(3):950-8. PMID: 21699789; PMCID: PMC3163814.
      Citations: 150     Fields:    Translation:Animals
    30. Chambers AP, Stefater MA, Wilson-Perez HE, Jessen L, Sisley S, Ryan KK, Gaitonde S, Sorrell JE, Toure M, D'Alessio DA, Sandoval DA, Seeley RJ, Woods SC, Berger J. Similar effects of roux-en-Y gastric bypass and vertical sleeve gastrectomy on glucose regulation in rats. Physiol Behav. 2011 Nov 30; 105(1):120-3. PMID: 21683726; PMCID: PMC3852684.
      Citations: 36     Fields:    Translation:Animals
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