"RNA, Double-Stranded" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA consisting of two strands as opposed to the more prevalent single-stranded RNA. Most of the double-stranded segments are formed from transcription of DNA by intramolecular base-pairing of inverted complementary sequences separated by a single-stranded loop. Some double-stranded segments of RNA are normal in all organisms.
| Descriptor ID |
D012330
|
| MeSH Number(s) |
D13.444.735.490 G02.111.570.820.486.775 G05.360.580.775
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "RNA, Double-Stranded".
Below are MeSH descriptors whose meaning is more specific than "RNA, Double-Stranded".
This graph shows the total number of publications written about "RNA, Double-Stranded" by people in this website by year, and whether "RNA, Double-Stranded" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 3 | 4 |
| 2006 | 1 | 2 | 3 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 2 | 2 |
| 2021 | 3 | 2 | 5 |
| 2022 | 1 | 1 | 2 |
| 2024 | 3 | 0 | 3 |
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Below are the most recent publications written about "RNA, Double-Stranded" by people in Profiles.
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IRE1a silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer. Cell. 2024 Dec 12; 187(25):7248-7266.e34.
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KAT2A and KAT2B prevent double-stranded RNA accumulation and interferon signaling to maintain intestinal stem cell renewal. Sci Adv. 2024 Aug 09; 10(32):eadl1584.
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hnRNPM protects against the dsRNA-mediated interferon response by repressing LINE-associated cryptic splicing. Mol Cell. 2024 Jun 06; 84(11):2087-2103.e8.
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Pin-Pointing the Key Hubs in the IFN-? Pathway Responding to SARS-CoV-2 Infection. Viruses. 2022 09 30; 14(10).
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Regulation of the double-stranded RNA response through ADAR1 licenses metaplastic reprogramming in gastric epithelium. JCI Insight. 2022 02 08; 7(3).
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WEE1 inhibition induces anti-tumor immunity by activating ERV and the dsRNA pathway. J Exp Med. 2022 01 03; 219(1).
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ADAR and hnRNPC deficiency synergize in activating endogenous dsRNA-induced type I IFN responses. J Exp Med. 2021 09 06; 218(9).
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Population scale nucleic acid delivery to Caenorhabditis elegans via electroporation. G3 (Bethesda). 2021 07 14; 11(7).
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Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. Cell. 2021 01 21; 184(2):384-403.e21.
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RNAi Screening to Identify Factors That Control Circular RNA Localization. Methods Mol Biol. 2021; 2209:321-332.