"Toyocamycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
4-Amino-5-cyano-7-(D-ribofuranosyl)-7H- pyrrolo(2,3-d)pyrimidine. Antibiotic antimetabolite isolated from Streptomyces toyocaensis cultures. It is an analog of adenosine, blocks RNA synthesis and ribosome function, and is used mainly as a tool in biochemistry.
| Descriptor ID |
D014127
|
| MeSH Number(s) |
D13.570.800.840
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Toyocamycin".
Below are MeSH descriptors whose meaning is more specific than "Toyocamycin".
This graph shows the total number of publications written about "Toyocamycin" by people in this website by year, and whether "Toyocamycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "Toyocamycin" by people in Profiles.
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Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA. 2006 May; 12(5):797-806.
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Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature. 2004 Sep 23; 431(7007):471-6.
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Drug-induced translocation of nucleolar proteins fused to green fluorescent protein. Methods Mol Biol. 2002; 183:151-61.
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Green fluorescent protein tag for studies of drug-induced translocation of nucleolar protein RH-II/Gu. Biotechniques. 1998 Jun; 24(6):1032-6.
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Effects of cytotoxic drugs on translocation of nucleolar RNA helicase RH-II/Gu. Exp Cell Res. 1997 Sep 15; 235(2):413-20.
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Structural and functional relationships of toyocamycin on NPM-translocation. Anticancer Drug Des. 1997 Apr; 12(3):205-15.