"Enkephalins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the three major families of endogenous opioid peptides. The enkephalins are pentapeptides that are widespread in the central and peripheral nervous systems and in the adrenal medulla.
| Descriptor ID |
D004745
|
| MeSH Number(s) |
D12.644.400.575.281 D12.776.631.650.575.281
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Enkephalins".
Below are MeSH descriptors whose meaning is more specific than "Enkephalins".
This graph shows the total number of publications written about "Enkephalins" by people in this website by year, and whether "Enkephalins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Enkephalins" by people in Profiles.
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Distinct basal forebrain-originated neural circuits promote homoeostatic feeding and suppress hedonic feeding in male mice. Nat Metab. 2024 Sep; 6(9):1775-1790.
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HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor Signaling. J Neurosci. 2022 10 19; 42(42):7862-7874.
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Moderation of buprenorphine therapy for cocaine dependence efficacy by variation of the Prodynorphin gene. Eur J Clin Pharmacol. 2022 Jun; 78(6):965-973.
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Enkephalins and the Opioid System of the Heart. Circ Heart Fail. 2019 05; 12(5):e005851.
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Novel fentanyl-based dual ?/d-opioid agonists for the treatment of acute and chronic pain. Life Sci. 2013 Dec 18; 93(25-26):1010-6.
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Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs. Pharmacogenet Genomics. 2011 Apr; 21(4):185-96.
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Cell-specific effects of variants of the 68-base pair tandem repeat on prodynorphin gene promoter activity. Addict Biol. 2011 Apr; 16(2):334-46.
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Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment. Ann N Y Acad Sci. 2010 Feb; 1187:184-207.
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A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain. Neuropsychopharmacology. 2009 Apr; 34(5):1185-97.
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Adenylyl cyclase-5 activity in the nucleus accumbens regulates anxiety-related behavior. J Neurochem. 2008 Oct; 107(1):105-15.