"Serine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
| Descriptor ID |
D012694
|
| MeSH Number(s) |
D12.125.154.800
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Serine".
Below are MeSH descriptors whose meaning is more specific than "Serine".
This graph shows the total number of publications written about "Serine" by people in this website by year, and whether "Serine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 3 | 5 |
| 1995 | 2 | 5 | 7 |
| 1996 | 4 | 1 | 5 |
| 1997 | 1 | 3 | 4 |
| 1998 | 2 | 2 | 4 |
| 1999 | 4 | 5 | 9 |
| 2000 | 0 | 7 | 7 |
| 2001 | 6 | 3 | 9 |
| 2002 | 1 | 6 | 7 |
| 2003 | 2 | 13 | 15 |
| 2004 | 6 | 13 | 19 |
| 2005 | 0 | 15 | 15 |
| 2006 | 1 | 15 | 16 |
| 2007 | 5 | 15 | 20 |
| 2008 | 3 | 12 | 15 |
| 2009 | 3 | 6 | 9 |
| 2010 | 3 | 12 | 15 |
| 2011 | 4 | 4 | 8 |
| 2012 | 2 | 4 | 6 |
| 2013 | 3 | 7 | 10 |
| 2014 | 2 | 1 | 3 |
| 2015 | 2 | 5 | 7 |
| 2016 | 4 | 8 | 12 |
| 2017 | 1 | 4 | 5 |
| 2018 | 2 | 5 | 7 |
| 2019 | 2 | 2 | 4 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 2 | 3 |
| 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "Serine" by people in Profiles.
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L-serine treatment in patients with GRIN-related encephalopathy: a phase 2A, non-randomized study. Brain. 2024 May 03; 147(5):1653-1666.
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Adipose Triglyceride Lipase Is a Therapeutic Target in Advanced Prostate Cancer That Promotes Metabolic Plasticity. Cancer Res. 2024 03 04; 84(5):703-724.
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Metabolic model predictions enable targeted microbiome manipulation through precision prebiotics. Microbiol Spectr. 2024 Feb 06; 12(2):e0114423.
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Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins. Commun Biol. 2022 09 19; 5(1):987.
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Genetic variants in ALDH1L1 and GLDC influence the serine-to-glycine ratio in Hispanic children. Am J Clin Nutr. 2022 08 04; 116(2):500-510.
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Phosphorylation of HORMA-domain protein HTP-3 at Serine 285 is dispensable for crossover formation. G3 (Bethesda). 2022 05 06; 12(5).
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Subchronic Tolerance Trials of Graded Oral Supplementation with Phenylalanine or Serine in Healthy Adults. Nutrients. 2021 Jun 08; 13(6).
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Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1. JCI Insight. 2021 02 08; 6(3).
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Phosphorylation Modulates the Coregulatory Protein Exchange of the Nuclear Receptor Pregnane X Receptor. J Pharmacol Exp Ther. 2020 06; 373(3):370-380.
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WIP1 dephosphorylation of p27Kip1 Serine 140 destabilizes p27Kip1 and reverses anti-proliferative effects of ATM phosphorylation. Cell Cycle. 2020 02; 19(4):479-491.