Xeroderma Pigmentosum Group D Protein
"Xeroderma Pigmentosum Group D Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA helicase that is a component of TRANSCRIPTION FACTOR TFIIH. It plays an essential role in NUCLEOTIDE EXCISION REPAIR, and mutations in this protein are associated with XERODERMA PIGMENTOSUM.
| Descriptor ID |
D051759
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| MeSH Number(s) |
D08.811.277.040.025.159.500 D08.811.399.340.500 D12.776.260.775.875.875.500 D12.776.930.930.875.875.500
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| Concept/Terms |
Xeroderma Pigmentosum Group D Protein- Xeroderma Pigmentosum Group D Protein
- Excision Repair Cross-Complementing Rodent Repair Deficiency, Group 2 Protein
- Excision Repair Cross Complementing Rodent Repair Deficiency, Group 2 Protein
- Xeroderma Pigmentosum Complementation Group D Protein
- ERCC2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Xeroderma Pigmentosum Group D Protein".
Below are MeSH descriptors whose meaning is more specific than "Xeroderma Pigmentosum Group D Protein".
This graph shows the total number of publications written about "Xeroderma Pigmentosum Group D Protein" by people in this website by year, and whether "Xeroderma Pigmentosum Group D Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 3 | 3 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 2 | 3 |
| 2016 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Xeroderma Pigmentosum Group D Protein" by people in Profiles.
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Tsutakawa SE, Tsai CL, Yan C, Bralic A, Chazin WJ, Hamdan SM, Schärer OD, Ivanov I, Tainer JA. Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair. DNA Repair (Amst). 2020 12; 96:102972.
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Banfield E, Brown AL, Peckham EC, Rednam SP, Murray J, Okcu MF, Mitchell LE, Chintagumpala MM, Lau CC, Scheurer ME, Lupo PJ. Exploratory analysis of ERCC2 DNA methylation in survival among pediatric medulloblastoma patients. Cancer Epidemiol. 2016 10; 44:161-166.
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Li Y, Liu Z, Liu H, Wang LE, Tan D, Ajani JA, Wei QY. ERCC1 and ERCC2 variants predict survival in gastric cancer patients. PLoS One. 2013; 8(9):e71994.
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Song X, Sturgis EM, Jin L, Wang Z, Wei Q, Li G. Variants in nucleotide excision repair core genes and susceptibility to recurrence of squamous cell carcinoma of the oropharynx. Int J Cancer. 2013 Aug 01; 133(3):695-704.
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Li C, Yin M, Wang LE, Amos CI, Zhu D, Lee JE, Gershenwald JE, Grimm EA, Wei Q. Polymorphisms of nucleotide excision repair genes predict melanoma survival. J Invest Dermatol. 2013 Jul; 133(7):1813-21.
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Vélez-Cruz R, Zadorin AS, Coin F, Egly JM. Sirt1 suppresses RNA synthesis after UV irradiation in combined xeroderma pigmentosum group D/Cockayne syndrome (XP-D/CS) cells. Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3):E212-20.
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Pehlivan D, Cefle K, Raams A, Ozturk S, Baykal C, Kleijer WJ, Palanduz S, Jaspers NG. A Turkish trichothiodystrophy patient with homozygous XPD mutation and genotype-phenotype relationship. J Dermatol. 2012 Dec; 39(12):1016-21.
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Sontz PA, Mui TP, Fuss JO, Tainer JA, Barton JK. DNA charge transport as a first step in coordinating the detection of lesions by repair proteins. Proc Natl Acad Sci U S A. 2012 Feb 07; 109(6):1856-61.
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Mui TP, Fuss JO, Ishida JP, Tainer JA, Barton JK. ATP-stimulated, DNA-mediated redox signaling by XPD, a DNA repair and transcription helicase. J Am Chem Soc. 2011 Oct 19; 133(41):16378-81.
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Fuss JO, Tainer JA. XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase. DNA Repair (Amst). 2011 Jul 15; 10(7):697-713.