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ERNESTINA MELICOFF-PORTILLO

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6701 FANNIN
Houston, TX 77030
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    U01AI077810     (SWEET, STUART C)Mar 1, 2008 - Feb 28, 2018
    NIH
    B-CELL TARGETED INDUCTION TO IMPROVE OUTCOMES IN PEDIATRIC LUNG TRANSPLANTATION
    Role: Co-Investigator
    MELICO17A0     (Ernestina Melicoff)Sep 1, 2017 - Aug 31, 2021
    Cystic Fibrosis Foundation Therapeutics
    Lung Clearance Index In Pediatric Lung Transplant Patients
    Role: PI

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Melicoff E, Ruiz FE, Hosek K, Mallory GB. Cystic fibrosis lung transplant recipients 10 years of age or younger: Predisposing factors for end-stage disease. Pediatr Pulmonol. 2022 06; 57(6):1513-1519. PMID: 35243829.
      Citations:    Fields:    Translation:HumansCells
    2. Hayes D, Melicoff-Portillo E, Ziady AG. Selection of lung transplant candidates: A pediatric perspective on the International Society for Heart and Lung Transplantation consensus document. J Heart Lung Transplant. 2022 Jul; 41(7):998-999. PMID: 35317952.
      Citations:    Fields:    Translation:Humans
    3. Rajan A, Weaver AM, Aloisio GM, Jelinski J, Johnson HL, Venable SF, McBride T, Aideyan L, Piedra FA, Ye X, Melicoff-Portillo E, Yerramilli MRK, Zeng XL, Mancini MA, Stossi F, Maresso AW, Kotkar SA, Estes MK, Blutt S, Avadhanula V, Piedra PA. The Human Nose Organoid Respiratory Virus Model: an Ex Vivo Human Challenge Model To Study Respiratory Syncytial Virus (RSV) and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Pathogenesis and Evaluate Therapeutics. mBio. 2022 Feb 15; e0351121. PMID: 35164569.
      Citations: 4     Fields:    
    4. Conrad CK, Hedlin H, Chin H, Hayes D, Heeger PS, Faro A, Goldfarb S, Melicoff-Portillo E, Thalachallour M, Odim J, Schecter M, Storch GA, Visner GA, Williams NM, Kesler K, Danziger-Isakov L, Sweet SC. Auto-inflammation and auto-immunity pathways are associated with emergence of BOS in pediatric lung transplantation. Pediatr Transplant. 2022 06; 26(4):e14247. PMID: 35146849.
      Citations:    Fields:    Translation:Humans
    5. Sweet SC, Armstrong B, Blatter J, Chin H, Conrad C, Goldfarb S, Hayes D, Heeger PS, Lyou V, Melicoff-Portillo E, Mohanakumar T, Odim J, Ravichandran R, Schecter M, Storch GA, Visner G, Williams NM, Danziger-Isakov L. CTOTC-08: A multicenter randomized controlled trial of rituximab induction to reduce antibody development and improve outcomes in pediatric lung transplant recipients. Am J Transplant. 2022 01; 22(1):230-244. PMID: 34599540.
      Citations: 1     Fields:    Translation:Humans
    6. Schrader A, Melicoff E, Munoz F, Mallory GB, Curry CV, Gazzaneo MC. Diagnosis and treatment of cryptococcal osteomyelitis in a pediatric lung transplant patient. Pediatr Transplant. 2022 Mar; 26(2):e14165. PMID: 34687575.
      Citations:    Fields:    Translation:Humans
    7. Stephens A, McKenzie D, Heinle J, Melicoff-Portillo E, Gazzaneo C, Coleman R, Adachi I. Central extracorporeal membrane oxygenation to lung transplantation after remote arterial switch operation. JTCVS Tech. 2021 Dec; 10:452-455. PMID: 34977782.
      Citations:    
    8. Rajan A, Weaver AM, Aloisio GM, Jelinski J, Johnson HL, Venable SF, McBride T, Aideyan L, Piedra FA, Ye X, Melicoff-Portillo E, Yerramilli MRK, Zeng XL, Mancini MA, Stossi F, Maresso AW, Kotkar SA, Estes MK, Blutt S, Avadhanula V, Piedra PA. The human nose organoid respiratory virus model: an ex-vivo human challenge model to study RSV and SARS-CoV-2 pathogenesis and evaluate therapeutics. bioRxiv. 2021 Jul 28. PMID: 34341793.
      Citations:    
    9. Duncan-Park S, Dunphy C, Becker J, D'Urso C, Annunziato R, Blatter J, Conrad C, Goldfarb SB, Hayes D, Melicoff E, Schecter M, Visner G, Armstrong B, Chin H, Kesler K, Williams NM, Odim JN, Sweet SC, Danziger-Isakov L, Shemesh E. Remote intervention engagement and outcomes in the Clinical Trials in Organ Transplantation in Children consortium multisite trial. Am J Transplant. 2021 09; 21(9):3112-3122. PMID: 33752251.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    10. Onyearugbulem C, Coss-Bu J, Gazzaneo MC, Melicoff E, Das S, Lam F, Mallory GB, Munoz FM. Infections Within the First Month After Pediatric Lung Transplantation: Epidemiology and Impact on Outcomes. J Pediatric Infect Dis Soc. 2021 Apr 03; 10(3):245-251. PMID: 32533840.
      Citations:    Fields:    Translation:Humans
    11. Melicoff E, Hayes D, Benden C. Lung transplantation as an intervention for pediatric pulmonary hypertension. Pediatr Pulmonol. 2021 03; 56(3):587-592. PMID: 33210834.
      Citations:    Fields:    Translation:Humans
    12. Goss MB, Galván NTN, Ruan W, Munoz FM, Brewer ED, O'Mahony CA, Melicoff-Portillo E, Dreyer WJ, Miloh TA, Cigarroa FG, Ranch D, Yoeli D, Adams MA, Koohmaraie S, Harter DM, Rana A, Cotton RT, Carter B, Patel S, Moreno NF, Leung DH, Goss JA. The pediatric solid organ transplant experience with COVID-19: An initial multi-center, multi-organ case series. Pediatr Transplant. 2021 05; 25(3):e13868. PMID: 32949098.
      Citations: 29     Fields:    Translation:Humans
    13. Ammerman E, Sweet SC, Storch GA, Buller RS, Mason S, Conrad C, Hayes D, Faro A, Goldfarb SB, Melicoff E, Schecter M, Visner G, Heeger PS, Mohanakumar T, Williams N, Danziger-Isakov L. Epidemiology and persistence of rhinovirus in pediatric lung transplantation. Transpl Infect Dis. 2020 Dec; 22(6):e13422. PMID: 32686323.
      Citations: 2     Fields:    Translation:HumansCells
    14. Agrusa JE, Kothari VD, Brown AL, Masand PM, Lewis GD, Teh BS, Paulino AC, Silva-Carmona MD, Melicoff E, Allen CE, Gramatges MM. Early evidence of pulmonary dysfunction in survivors of childhood Hodgkin lymphoma. Leuk Lymphoma. 2020 10; 61(10):2419-2427. PMID: 32519904.
      Citations:    Fields:    Translation:Humans
    15. Moore PE, Boyer D, Perkins R, Katz ES, Castro-Codesal ML, MacLean JE, Akil N, Esther CR, Kaslow J, Lewis TC, Krone KA, Quizon A, Simpson R, Benscoter D, Spielberg DR, Melicoff E, Kuklinski CA, Blatter JA, Dy J, Rettig JS, Horani A, Gross J. American Thoracic Society 2019 Pediatric Core Curriculum. Pediatr Pulmonol. 2019 12; 54(12):1880-1894. PMID: 31456278.
      Citations:    Fields:    Translation:Humans
    16. Sweet SC, Chin H, Conrad C, Hayes D, Heeger PS, Faro A, Goldfarb S, Melicoff-Portillo E, Mohanakumar T, Odim J, Schecter M, Storch GA, Visner G, Williams NM, Kesler K, Danziger-Isakov L. Absence of evidence that respiratory viral infections influence pediatric lung transplantation outcomes: Results of the CTOTC-03 study. Am J Transplant. 2019 12; 19(12):3284-3298. PMID: 31216376.
      Citations: 4     Fields:    Translation:HumansCells
    17. Nguyen HN, Das S, Gazzaneo MC, Melicoff E, Mallory GB, Eldin KW, Guillerman RP. Clinico-radiologic features of pleuroparenchymal fibroelastosis in children. Pediatr Radiol. 2019 08; 49(9):1163-1170. PMID: 31004186.
      Citations: 1     Fields:    Translation:Humans
    18. Onyearugbulem C, Williams L, Zhu H, Gazzaneo MC, Melicoff E, Das S, Coss-Bu J, Lam F, Mallory G, Munoz FM. Risk factors for infection after pediatric lung transplantation. Transpl Infect Dis. 2018 Dec; 20(6):e13000. PMID: 30221817.
      Citations: 2     Fields:    Translation:Humans
    19. Blatter JA, Sweet SC, Conrad C, Danziger-Isakov LA, Faro A, Goldfarb SB, Hayes D, Melicoff E, Schecter M, Storch G, Visner GA, Williams NM, Wang D. Anellovirus loads are associated with outcomes in pediatric lung transplantation. Pediatr Transplant. 2018 02; 22(1). PMID: 29082660.
      Citations: 18     Fields:    Translation:HumansCells
    20. Ammerman E, Sweet SC, Fenchel M, Storch GA, Conrad C, Hayes D, Faro A, Goldfarb S, Melicoff E, Schecter M, Visner G, Williams NM, Danziger-Isakov L. Risk and outcomes of pulmonary fungal infection after pediatric lung transplantation. Clin Transplant. 2017 Nov; 31(11). PMID: 28871606.
      Citations: 2     Fields:    Translation:Humans
    21. Parrish A, Fenchel M, Storch GA, Buller R, Mason S, Williams N, Ikle D, Conrad C, Faro A, Goldfarb S, Hayes D, Melicoff-Portillo E, Schecter M, Visner G, Sweet S, Danziger-Isakov L. Epstein-Barr viral loads do not predict post-transplant lymphoproliferative disorder in pediatric lung transplant recipients: A multicenter prospective cohort study. Pediatr Transplant. 2017 Sep; 21(6). PMID: 28639398.
      Citations: 1     Fields:    Translation:HumansCells
    22. Scully BB, Goss M, Liu H, Keuht ML, Adachi I, McKenzie ED, Fraser CD, Melicoff E, Mallory GB, Heinle JS, Rana A. Waiting list outcomes in pediatric lung transplantation: Poor results for children listed in adult transplant programs. J Heart Lung Transplant. 2017 Nov; 36(11):1201-1208. PMID: 28579113.
      Citations: 1     Fields:    Translation:Humans
    23. Das S, Melicoff-Portillo E, Sockrider M. Lung Transplantation in Children. Am J Respir Crit Care Med. 2016 08 15; 194(4):P7-8. PMID: 27525467.
      Citations:    Fields:    Translation:Humans
    24. Garcia-Morales LJ, Chen NY, Weng T, Luo F, Davies J, Philip K, Volcik KA, Melicoff E, Amione-Guerra J, Bunge RR, Bruckner BA, Loebe M, Eltzschig HK, Pandit LM, Blackburn MR, Karmouty-Quintana H. Altered Hypoxic-Adenosine Axis and Metabolism in Group III Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2016 Apr; 54(4):574-83. PMID: 26414702.
      Citations: 23     Fields:    Translation:Humans
    25. Guzman-Pruneda FA, Orr Y, Trost JG, Zhang W, Das S, Melicoff E, Maddox J, Nugent M, Mery CM, Adachi I, Schecter MG, Mallory GB, Morales DL, Heinle JS, McKenzie ED. Bronchial artery revascularization and en bloc lung transplant in children. J Heart Lung Transplant. 2016 Jan; 35(1):122-129. PMID: 26508727.
      Citations: 3     Fields:    Translation:Humans
    26. Weng T, Poth JM, Karmouty-Quintana H, Garcia-Morales LJ, Melicoff E, Luo F, Chen NY, Evans CM, Bunge RR, Bruckner BA, Loebe M, Volcik KA, Eltzschig HK, Blackburn MR. Hypoxia-induced deoxycytidine kinase contributes to epithelial proliferation in pulmonary fibrosis. Am J Respir Crit Care Med. 2014 Dec 15; 190(12):1402-12. PMID: 25358054.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    27. Le TT, Karmouty-Quintana H, Melicoff E, Le TT, Weng T, Chen NY, Pedroza M, Zhou Y, Davies J, Philip K, Molina J, Luo F, George AT, Garcia-Morales LJ, Bunge RR, Bruckner BA, Loebe M, Seethamraju H, Agarwal SK, Blackburn MR. Blockade of IL-6 Trans signaling attenuates pulmonary fibrosis. J Immunol. 2014 Oct 01; 193(7):3755-68. PMID: 25172494.
      Citations: 108     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    28. Karmouty-Quintana H, Zhong H, Acero L, Weng T, Melicoff E, West JD, Hemnes A, Grenz A, Eltzschig HK, Blackwell TS, Xia Y, Johnston RA, Zeng D, Belardinelli L, Blackburn MR. The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease. FASEB J. 2012 Jun; 26(6):2546-57. PMID: 22415303.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    29. Wu XS, McNeil BD, Xu J, Fan J, Xue L, Melicoff E, Adachi R, Bai L, Wu LG. Ca(2+) and calmodulin initiate all forms of endocytosis during depolarization at a nerve terminal. Nat Neurosci. 2009 Aug; 12(8):1003-1010. PMID: 19633667.
      Citations: 121     Fields:    Translation:AnimalsCells
    30. Melicoff E, Sansores-Garcia L, Gomez A, Moreira DC, Datta P, Thakur P, Petrova Y, Siddiqi T, Murthy JN, Dickey BF, Heidelberger R, Adachi R. Synaptotagmin-2 controls regulated exocytosis but not other secretory responses of mast cells. J Biol Chem. 2009 Jul 17; 284(29):19445-51. PMID: 19473977.
      Citations: 25     Fields:    Translation:AnimalsCells
    31. He L, Xue L, Xu J, McNeil BD, Bai L, Melicoff E, Adachi R, Wu LG. Compound vesicle fusion increases quantal size and potentiates synaptic transmission. Nature. 2009 May 07; 459(7243):93-7. PMID: 19279571.
      Citations: 63     Fields:    Translation:AnimalsCells
    32. Tuvim MJ, Mospan AR, Burns KA, Chua M, Mohler PJ, Melicoff E, Adachi R, Ammar-Aouchiche Z, Davis CW, Dickey BF. Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum. J Biol Chem. 2009 Apr 10; 284(15):9781-7. PMID: 19208631.
      Citations: 30     Fields:    Translation:AnimalsCells
    33. Clement CG, Evans SE, Evans CM, Hawke D, Kobayashi R, Reynolds PR, Moghaddam SJ, Scott BL, Melicoff E, Adachi R, Dickey BF, Tuvim MJ. Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice. Am J Respir Crit Care Med. 2008 Jun 15; 177(12):1322-30. PMID: 18388354.
      Citations: 64     Fields:    Translation:AnimalsCells
    34. Thakurdas SM, Melicoff E, Sansores-Garcia L, Moreira DC, Petrova Y, Stevens RL, Adachi R. The mast cell-restricted tryptase mMCP-6 has a critical immunoprotective role in bacterial infections. J Biol Chem. 2007 Jul 20; 282(29):20809-15. PMID: 17456473.
      Citations: 84     Fields:    Translation:AnimalsCells
    35. Pang ZP, Melicoff E, Padgett D, Liu Y, Teich AF, Dickey BF, Lin W, Adachi R, Südhof TC. Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapses. J Neurosci. 2006 Dec 27; 26(52):13493-504. PMID: 17192432.
      Citations: 106     Fields:    Translation:AnimalsCells
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