JNK Mitogen-Activated Protein Kinases
"JNK Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.
| Descriptor ID |
D048031
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567.374 D12.644.360.450.340 D12.776.476.450.340
|
| Concept/Terms |
JNK Mitogen-Activated Protein Kinases- JNK Mitogen-Activated Protein Kinases
- JNK Mitogen Activated Protein Kinases
- jun-NH2-Terminal Kinase
- jun NH2 Terminal Kinase
- jun-NH2-Terminal Kinases
- jun NH2 Terminal Kinases
- c-jun Amino-Terminal Kinase
- Amino-Terminal Kinase, c-jun
- c jun Amino Terminal Kinase
- c-jun N-Terminal Kinase
- N-Terminal Kinase, c-jun
- c jun N Terminal Kinase
|
Below are MeSH descriptors whose meaning is more general than "JNK Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "JNK Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "JNK Mitogen-Activated Protein Kinases" by people in this website by year, and whether "JNK Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 3 | 3 |
| 1998 | 2 | 8 | 10 |
| 1999 | 3 | 6 | 9 |
| 2000 | 2 | 10 | 12 |
| 2001 | 0 | 7 | 7 |
| 2002 | 3 | 9 | 12 |
| 2003 | 5 | 11 | 16 |
| 2004 | 6 | 3 | 9 |
| 2005 | 8 | 13 | 21 |
| 2006 | 6 | 7 | 13 |
| 2007 | 6 | 2 | 8 |
| 2008 | 8 | 6 | 14 |
| 2009 | 5 | 6 | 11 |
| 2010 | 5 | 6 | 11 |
| 2011 | 2 | 2 | 4 |
| 2012 | 0 | 5 | 5 |
| 2013 | 3 | 3 | 6 |
| 2014 | 3 | 1 | 4 |
| 2015 | 4 | 3 | 7 |
| 2016 | 3 | 2 | 5 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 2 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 2 | 3 |
| 2021 | 0 | 3 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "JNK Mitogen-Activated Protein Kinases" by people in Profiles.
-
Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation. Nat Commun. 2021 08 11; 12(1):4853.
-
Protein Phosphatase 4 Promotes Hepatocyte Lipoapoptosis by Regulating RAC1/MLK3/JNK Pathway. Oxid Med Cell Longev. 2021; 2021:5550498.
-
Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway. PLoS One. 2021; 16(5):e0252541.
-
Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells. Chem Biol Interact. 2020 Nov 01; 331:109279.
-
JNK signaling contributes to skeletal muscle wasting and protein turnover in pancreatic cancer cachexia. Cancer Lett. 2020 10 28; 491:70-77.
-
JNK Signaling in Stem Cell Self-Renewal and Differentiation. Int J Mol Sci. 2020 Apr 09; 21(7).
-
The TGF?1 Receptor Antagonist GW788388 Reduces JNK Activation and Protects Against Acetaminophen Hepatotoxicity in Mice. Toxicol Sci. 2019 05 01; 170(2):549-561.
-
Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice. Redox Biol. 2019 04; 22:101148.
-
Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest. Cell Physiol Biochem. 2018; 49(2):512-529.
-
Deltex interacts with Eiger and consequently influences the cell death in Drosophila melanogaster. Cell Signal. 2018 Sep; 49:17-29.