Extracellular Signal-Regulated MAP Kinases
"Extracellular Signal-Regulated MAP Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.
| Descriptor ID |
D048049
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567.249 D12.644.360.450.169 D12.776.476.450.169
|
| Concept/Terms |
Extracellular Signal-Regulated MAP Kinases- Extracellular Signal-Regulated MAP Kinases
- Extracellular Signal Regulated MAP Kinases
- MAP Kinases, Extracellular Signal-Regulated
- MAP Kinases, Extracellular Signal Regulated
- ERK MAP Kinases
- Extracellular Signal-Regulated Kinases
- Extracellular Signal Regulated Kinases
- Kinases, Extracellular Signal-Regulated
|
Below are MeSH descriptors whose meaning is more general than "Extracellular Signal-Regulated MAP Kinases".
Below are MeSH descriptors whose meaning is more specific than "Extracellular Signal-Regulated MAP Kinases".
This graph shows the total number of publications written about "Extracellular Signal-Regulated MAP Kinases" by people in this website by year, and whether "Extracellular Signal-Regulated MAP Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 6 | 15 | 21 |
| 2006 | 4 | 16 | 20 |
| 2007 | 8 | 24 | 32 |
| 2008 | 7 | 15 | 22 |
| 2009 | 6 | 9 | 15 |
| 2010 | 8 | 18 | 26 |
| 2011 | 4 | 18 | 22 |
| 2012 | 4 | 17 | 21 |
| 2013 | 3 | 10 | 13 |
| 2014 | 1 | 8 | 9 |
| 2015 | 7 | 6 | 13 |
| 2016 | 5 | 7 | 12 |
| 2017 | 4 | 6 | 10 |
| 2018 | 0 | 4 | 4 |
| 2019 | 2 | 4 | 6 |
| 2020 | 1 | 6 | 7 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 4 | 4 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Extracellular Signal-Regulated MAP Kinases" by people in Profiles.
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An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma. Cell Rep. 2024 01 23; 43(1):113557.
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Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors. Science. 2023 09 08; 381(6662):eabn4180.
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Recombinant Thrombomodulin Has Anti-tumor Effects and Enhances the Effects of Gemcitabine for Pancreatic Cancer Through G-protein Coupled Receptor 15. Anticancer Res. 2022 Oct; 42(10):4679-4687.
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Regulation of oocyte maturation: Role of conserved ERK signaling. Mol Reprod Dev. 2022 09; 89(9):353-374.
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AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill FLT3-ITD acute myeloid leukemia. Haematologica. 2022 06 01; 107(6):1311-1322.
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Cyclin D1 expression in Rosai-Dorfman disease: a near-constant finding that is not invariably associated with mitogen-activated protein kinase/extracellular signal-regulated kinase pathway activation. Hum Pathol. 2022 03; 121:36-45.
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Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer. Elife. 2021 06 14; 10.
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Characterization and management of ERK inhibitor associated dermatologic adverse events: analysis from a nonrandomized trial of ulixertinib for advanced cancers. Invest New Drugs. 2021 06; 39(3):785-795.
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Transforming growth factor beta signaling and decidual integrity in mice?. Biol Reprod. 2020 12 01; 103(6):1186-1198.
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Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation. Mol Cell. 2020 11 19; 80(4):633-647.e7.