NAD(P)H Dehydrogenase (Quinone)
"NAD(P)H Dehydrogenase (Quinone)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein that reversibly catalyzes the oxidation of NADH or NADPH by various quinones and oxidation-reduction dyes. The enzyme is inhibited by dicoumarol, capsaicin, and caffeine.
| Descriptor ID |
D016660
|
| MeSH Number(s) |
D08.811.682.608.800.500
|
| Concept/Terms |
NAD(P)H Dehydrogenase (Quinone)- NAD(P)H Dehydrogenase (Quinone)
- Quinone Reductase
- Reductase, Quinone
- Phylloquinone Reductase
- Reductase, Phylloquinone
- DT Diaphorase
- Diaphorase, DT
- Menadione Reductase
- Reductase, Menadione
|
Below are MeSH descriptors whose meaning is more general than "NAD(P)H Dehydrogenase (Quinone)".
Below are MeSH descriptors whose meaning is more specific than "NAD(P)H Dehydrogenase (Quinone)".
This graph shows the total number of publications written about "NAD(P)H Dehydrogenase (Quinone)" by people in this website by year, and whether "NAD(P)H Dehydrogenase (Quinone)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1997 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 1 | 3 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "NAD(P)H Dehydrogenase (Quinone)" by people in Profiles.
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Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells. Oxid Med Cell Longev. 2021; 2021:5544600.
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Compound NSC84167 selectively targets NRF2-activated pancreatic cancer by inhibiting asparagine synthesis pathway. Cell Death Dis. 2021 07 10; 12(7):693.
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Cell-specific regulation of Nrf2 during ROS-Dependent cell death caused by 2,3,5-tris(glutathion-S-yl)hydroquinone (TGHQ). Chem Biol Interact. 2019 Apr 01; 302:1-10.
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Quercetin attenuates the hyperoxic lung injury in neonatal mice: Implications for Bronchopulmonary dysplasia (BPD). Food Chem Toxicol. 2018 Apr; 114:23-33.
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Inflammation, oxidative stress, and higher expression levels of Nrf2 and NQO1 proteins in the airways of women chronically exposed to biomass fuel smoke. Mol Cell Biochem. 2018 Oct; 447(1-2):63-76.
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Hyperoxia-mediated transcriptional activation of cytochrome P4501A1 (CYP1A1) and decreased susceptibility to oxygen-mediated lung injury in newborn mice. Biochem Biophys Res Commun. 2018 01 01; 495(1):408-413.
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Phase I Study of Amrubicin and Cyclophosphamide in Patients With Advanced Solid Organ Malignancies: HOG LUN 07-130. Am J Clin Oncol. 2017 Aug; 40(4):329-335.
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A tool for discovering drug sensitivity and gene expression associations in cancer cells. PLoS One. 2017; 12(4):e0176763.
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Leflunomide induces NAD(P)H quinone dehydrogenase 1 enzyme via the aryl hydrocarbon receptor in neonatal mice. Biochem Biophys Res Commun. 2017 03 25; 485(1):195-200.
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Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors. Cancer Cell. 2016 Dec 12; 30(6):940-952.