Protein Tyrosine Phosphatases
"Protein Tyrosine Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme group that specifically dephosphorylates phosphotyrosyl residues in selected proteins. Together with PROTEIN-TYROSINE KINASE, it regulates tyrosine phosphorylation and dephosphorylation in cellular signal transduction and may play a role in cell growth control and carcinogenesis.
| Descriptor ID |
D017027
|
| MeSH Number(s) |
D08.811.277.352.650.775
|
| Concept/Terms |
Protein Tyrosine Phosphatases- Protein Tyrosine Phosphatases
- Phosphatases, Protein Tyrosine
- Tyrosine Phosphatases, Protein
- Phosphotyrosyl Protein Phosphatase
- Phosphatase, Phosphotyrosyl Protein
- Protein Phosphatase, Phosphotyrosyl
- Protein-Tyrosine Phosphatase
- Phosphatase, Protein-Tyrosine
- PTPase
- Tyrosyl Phosphoprotein Phosphatase
- Phosphatase, Tyrosyl Phosphoprotein
- Phosphoprotein Phosphatase, Tyrosyl
- Phosphotyrosine Phosphatase
- Phosphatase, Phosphotyrosine
- Protein-Tyrosine-Phosphatase
- Protein Tyrosine Phosphatase
|
Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatases".
This graph shows the total number of publications written about "Protein Tyrosine Phosphatases" by people in this website by year, and whether "Protein Tyrosine Phosphatases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 1 | 1 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 2 | 0 | 2 |
| 2004 | 5 | 1 | 6 |
| 2005 | 4 | 2 | 6 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 1 | 3 |
| 2018 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Tyrosine Phosphatases" by people in Profiles.
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A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3. Am J Hum Genet. 2024 01 04; 111(1):96-118.
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The Rare and Atypical Diabetes Network (RADIANT) Study: Design and Early Results. Diabetes Care. 2023 06 01; 46(6):1265-1270.
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Altered nociception in Alzheimer disease is associated with striatal-enriched protein tyrosine phosphatase signaling. Pain. 2021 06 01; 162(6):1669-1680.
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Prolyl Hydroxylase Domain-2 Protein Regulates Lipopolysaccharide-Induced Vascular Inflammation. Am J Pathol. 2019 01; 189(1):200-213.
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SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. J Am Soc Nephrol. 2017 Mar; 28(3):981-994.
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Whole-exome sequencing in the molecular diagnosis of individuals with congenital anomalies of the kidney and urinary tract and identification of a new causative gene. Genet Med. 2017 04; 19(4):412-420.
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Phosphatase PTP4A3 Promotes Triple-Negative Breast Cancer Growth and Predicts Poor Patient Survival. Cancer Res. 2016 04 01; 76(7):1942-53.
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Anti-miR-148a regulates platelet Fc?RIIA signaling and decreases thrombosis in vivo in mice. Blood. 2015 Dec 24; 126(26):2871-81.
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Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair. Mol Cell Biol. 2015 Nov; 35(21):3657-68.
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Eyes absent tyrosine phosphatase activity is not required for Drosophila development or survival. PLoS One. 2013; 8(3):e58818.