Transcription Factor AP-1
"Transcription Factor AP-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multiprotein complex composed of the products of c-jun and c-fos proto-oncogenes. These proteins must dimerize in order to bind to the AP-1 recognition site, also known as the TPA-responsive element (TRE). AP-1 controls both basal and inducible transcription of several genes.
| Descriptor ID |
D018808
|
| MeSH Number(s) |
D12.776.260.108.875 D12.776.930.127.875
|
| Concept/Terms |
Transcription Factor AP-1- Transcription Factor AP-1
- Transcription Factor AP 1
- AP-1 Enhancer-Binding Protein
- Enhancer-Binding Protein, AP-1
- AP-1
- Activator Protein-1
- Activator Protein 1
- AP-1 Enhancer Binding Protein
- AP 1 Enhancer Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor AP-1".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor AP-1".
This graph shows the total number of publications written about "Transcription Factor AP-1" by people in this website by year, and whether "Transcription Factor AP-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 2 | 3 |
| 1996 | 8 | 1 | 9 |
| 1997 | 3 | 1 | 4 |
| 1998 | 0 | 3 | 3 |
| 1999 | 4 | 4 | 8 |
| 2000 | 3 | 4 | 7 |
| 2001 | 4 | 10 | 14 |
| 2002 | 4 | 2 | 6 |
| 2003 | 4 | 5 | 9 |
| 2004 | 8 | 5 | 13 |
| 2005 | 4 | 6 | 10 |
| 2006 | 4 | 4 | 8 |
| 2007 | 3 | 5 | 8 |
| 2008 | 4 | 4 | 8 |
| 2009 | 2 | 6 | 8 |
| 2010 | 2 | 2 | 4 |
| 2011 | 2 | 4 | 6 |
| 2012 | 2 | 2 | 4 |
| 2013 | 1 | 2 | 3 |
| 2014 | 0 | 4 | 4 |
| 2015 | 1 | 4 | 5 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2019 | 0 | 3 | 3 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 2 | 3 |
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Below are the most recent publications written about "Transcription Factor AP-1" by people in Profiles.
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MIF/NR3C2 axis regulates glucose metabolism reprogramming in pancreatic cancer through MAPK-ERK and AP-1 pathways. Carcinogenesis. 2024 Aug 12; 45(8):582-594.
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TERT activation targets DNA methylation and multiple aging hallmarks. Cell. 2024 Jul 25; 187(15):4030-4042.e13.
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SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation. Commun Biol. 2024 01 09; 7(1):67.
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Assigning pathogenicity for TAB2 variants using a novel scalable functional assay and expanding TAB2 disease spectrum. Hum Mol Genet. 2023 03 06; 32(6):959-970.
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Clearance of HIV-1 or SIV reservoirs by promotion of apoptosis and inhibition of autophagy: Targeting intracellular molecules in cure-directed strategies. J Leukoc Biol. 2022 11; 112(5):1245-1259.
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Interferon Signaling in Estrogen Receptor-positive Breast Cancer: A Revitalized Topic. Endocrinology. 2022 01 01; 163(1).
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CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity. Nat Cancer. 2021 01; 2(1):34-48.
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Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance. Nat Cell Biol. 2020 06; 22(6):701-715.
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Human RAP1 specifically protects telomeres of senescent cells from DNA damage. EMBO Rep. 2020 04 03; 21(4):e49076.
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Conserved NPPB+ Border Zone Switches From MEF2- to AP-1-Driven Gene Program. Circulation. 2019 09 09; 140(10):864-879.