"Endonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the hydrolysis of the internal bonds and thereby the formation of polynucleotides or oligonucleotides from ribo- or deoxyribonucleotide chains. EC 3.1.-.
| Descriptor ID |
D004720
|
| MeSH Number(s) |
D08.811.277.352.355
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Endonucleases".
Below are MeSH descriptors whose meaning is more specific than "Endonucleases".
This graph shows the total number of publications written about "Endonucleases" by people in this website by year, and whether "Endonucleases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 4 | 2 | 6 |
| 1995 | 6 | 1 | 7 |
| 1996 | 2 | 0 | 2 |
| 1997 | 3 | 1 | 4 |
| 1998 | 2 | 1 | 3 |
| 1999 | 5 | 1 | 6 |
| 2000 | 4 | 2 | 6 |
| 2001 | 2 | 1 | 3 |
| 2002 | 3 | 1 | 4 |
| 2003 | 0 | 2 | 2 |
| 2004 | 3 | 2 | 5 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 3 | 3 | 6 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 2 | 3 |
| 2010 | 2 | 5 | 7 |
| 2011 | 3 | 1 | 4 |
| 2012 | 2 | 2 | 4 |
| 2013 | 4 | 2 | 6 |
| 2014 | 4 | 1 | 5 |
| 2015 | 2 | 4 | 6 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 1 | 3 |
| 2019 | 5 | 1 | 6 |
| 2020 | 2 | 1 | 3 |
| 2023 | 1 | 3 | 4 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endonucleases" by people in Profiles.
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Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair. Nat Commun. 2024 Oct 01; 15(1):8511.
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Loss of the methylarginine reader function of SND1 confers resistance to hepatocellular carcinoma. Biochem J. 2023 11 29; 480(22):1805-1816.
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Leveraging QM/MM and Molecular Dynamics Simulations to Decipher the Reaction Mechanism of the Cas9 HNH Domain to Investigate Off-Target Effects. J Chem Inf Model. 2023 11 13; 63(21):6834-6850.
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DNA2 Nuclease Inhibition Confers Synthetic Lethality in Cancers with Mutant p53 and Synergizes with PARP Inhibitors. Cancer Res Commun. 2023 10 16; 3(10):2096-2112.
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A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair. Nucleic Acids Res. 2023 02 22; 51(3):1019-1033.
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Human EXOG Possesses Strong AP Hydrolysis Activity: Implication on Mitochondrial DNA Base Excision Repair. J Am Chem Soc. 2022 12 28; 144(51):23543-23550.
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A Rad51-independent pathway promotes single-strand template repair in gene editing. PLoS Genet. 2020 10; 16(10):e1008689.
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Baloxavir Marboxil Single-dose Treatment in Influenza-infected Children: A Randomized, Double-blind, Active Controlled Phase 3 Safety and Efficacy Trial (miniSTONE-2). Pediatr Infect Dis J. 2020 08; 39(8):700-705.
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Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations. Proc Natl Acad Sci U S A. 2020 06 23; 117(25):14127-14138.
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SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair. Nucleic Acids Res. 2019 11 04; 47(19):10181-10201.