"Epistasis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
| Descriptor ID |
D004843
|
| MeSH Number(s) |
G05.308.207
|
| Concept/Terms |
Epistasis, Genetic- Epistasis, Genetic
- Epistases, Genetic
- Gene-Gene Interactions, Epistatic
- Gene Gene Interactions, Epistatic
- Gene-Gene Interaction, Epistatic
- Epistatic Gene-Gene Interaction
- Epistatic Gene-Gene Interactions
- Gene Gene Interaction, Epistatic
- Interaction, Epistatic Gene-Gene
- Interactions, Epistatic Gene-Gene
- Non-Allelic Gene Interactions
- Gene Interaction, Non-Allelic
- Gene Interactions, Non-Allelic
- Interaction, Non-Allelic Gene
- Interactions, Non-Allelic Gene
- Non Allelic Gene Interactions
- Non-Allelic Gene Interaction
- Genetic Epistasis
- Genetic Epistases
|
Below are MeSH descriptors whose meaning is more general than "Epistasis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epistasis, Genetic".
This graph shows the total number of publications written about "Epistasis, Genetic" by people in this website by year, and whether "Epistasis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 2 | 1 | 3 |
| 2005 | 2 | 3 | 5 |
| 2006 | 3 | 3 | 6 |
| 2007 | 2 | 3 | 5 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 4 | 4 |
| 2012 | 3 | 1 | 4 |
| 2013 | 3 | 2 | 5 |
| 2014 | 6 | 2 | 8 |
| 2015 | 2 | 3 | 5 |
| 2016 | 2 | 3 | 5 |
| 2017 | 1 | 4 | 5 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 2 | 3 |
| 2020 | 0 | 2 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Epistasis, Genetic" by people in Profiles.
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Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Mol Psychiatry. 2021 Jun; 26(6):2111-2125.
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Synergistic effects of functionally distinct substitutions in ?-lactamase variants shed light on the evolution of bacterial drug resistance. J Biol Chem. 2018 11 16; 293(46):17971-17984.
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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Am J Hum Genet. 2018 Mar 01; 102(3):375-400.
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Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13. Proc Natl Acad Sci U S A. 2015 Jul 28; 112(30):9328-33.
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Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks. Genome Res. 2015 Feb; 25(2):257-67.
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Evaluation of allelic strength of human TET2 mutations and cooperation between Tet2 knockdown and oncogenic Nras mutation. Br J Haematol. 2014 Aug; 166(3):461-5.
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Natural and orthogonal model for estimating gene-gene interactions applied to cutaneous melanoma. Hum Genet. 2014 May; 133(5):559-74.
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The interaction of polymorphisms of IL10 and DBH was associated with general symptoms of PANSS with TD in Chinese Han schizophrenic patients. PLoS One. 2013; 8(8):e70963.
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Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3. PLoS One. 2013; 8(3):e58830.
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HSD3B and gene-gene interactions in a pathway-based analysis of genetic susceptibility to bladder cancer. PLoS One. 2012; 7(12):e51301.