"Ion Channel Gating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.
| Descriptor ID |
D015640
|
| MeSH Number(s) |
G02.111.820.400 G04.835.400 G07.265.625
|
| Concept/Terms |
Ion Channel Gating- Ion Channel Gating
- Gating, Ion Channel
- Gatings, Ion Channel
- Ion Channel Gatings
|
Below are MeSH descriptors whose meaning is more general than "Ion Channel Gating".
Below are MeSH descriptors whose meaning is more specific than "Ion Channel Gating".
This graph shows the total number of publications written about "Ion Channel Gating" by people in this website by year, and whether "Ion Channel Gating" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 2 | 4 |
| 1996 | 1 | 3 | 4 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 3 | 3 |
| 1999 | 4 | 4 | 8 |
| 2000 | 3 | 3 | 6 |
| 2001 | 2 | 1 | 3 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 2 | 3 |
| 2004 | 4 | 6 | 10 |
| 2005 | 6 | 5 | 11 |
| 2006 | 3 | 3 | 6 |
| 2007 | 0 | 4 | 4 |
| 2008 | 3 | 4 | 7 |
| 2009 | 1 | 3 | 4 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 2 | 2 |
| 2012 | 3 | 2 | 5 |
| 2013 | 2 | 3 | 5 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 4 | 5 |
| 2017 | 2 | 0 | 2 |
| 2018 | 6 | 0 | 6 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ion Channel Gating" by people in Profiles.
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Transmembrane determinants of voltage-gating differences between BK (Slo1) and Slo3 channels. Biophys J. 2024 07 16; 123(14):2154-2166.
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BK channel modulation by positively charged peptides and auxiliary ? subunits mediated by the Ca2+-bowl site. J Gen Physiol. 2023 06 05; 155(6).
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The leucine-rich repeat domains of BK channel auxiliary ? subunits regulate their expression, trafficking, and channel-modulation functions. J Biol Chem. 2022 03; 298(3):101664.
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KCNQ channel PIP2 modulation: Two loose links, three rings, and a twist. Neuron. 2022 01 19; 110(2):178-180.
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Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na+ Channel 1.2 Macromolecular Complex. Cells. 2021 11 10; 10(11).
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A phase 3, randomized, double-blind, parallel-group study to evaluate tezacaftor/ivacaftor in people with cystic fibrosis heterozygous for F508del-CFTR and a gating mutation. J Cyst Fibros. 2021 03; 20(2):234-242.
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Design, Synthesis, and Pharmacological Evaluation of Analogues Derived from the PLEV Tetrapeptide as Protein-Protein Interaction Modulators of Voltage-Gated Sodium Channel 1.6. J Med Chem. 2020 10 22; 63(20):11522-11547.
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Molecular characterization and distribution of the voltage-gated sodium channel, Para, in the brain of the grasshopper and vinegar fly. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2020 03; 206(2):289-307.
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Protein Phosphatase 2A Regulates Cardiac Na+ Channels. Circ Res. 2019 03; 124(5):737-746.
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Efficiency measures the conversion of agonist binding energy into receptor conformational change. J Gen Physiol. 2019 04 01; 151(4):465-477.