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FARHAD R. DANESH

TitleProfessor
InstitutionMD Anderson
DepartmentEmergency Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Galvan DL, Long J, Green N, Chang BH, Lin JS, Schumacker PT, Truong LD, Overbeek P, Danesh FR. Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice. J Clin Invest. 2019 May 07; 130. PMID: 31063459.
      View in: PubMed
    2. Long J, Danesh FR. Values and Limitations of Targeting lncRNAs in Diabetic Nephropathy. Diabetes. 2018 04; 67(4):552-553. PMID: 29559513.
      View in: PubMed
    3. Galvan DL, Green NH, Danesh FR. The hallmarks of mitochondrial dysfunction in chronic kidney disease. Kidney Int. 2017 11; 92(5):1051-1057. PMID: 28893420.
      View in: PubMed
    4. Galvan DL, Badal SS, Long J, Chang BH, Schumacker PT, Overbeek PA, Danesh FR. Real-time in vivo mitochondrial redox assessment confirms enhanced mitochondrial reactive oxygen species in diabetic nephropathy. Kidney Int. 2017 11; 92(5):1282-1287. PMID: 28754553.
      View in: PubMed
    5. Galvan DL, Danesh FR. ß2-adrenergic receptors in inflammation and vascular complications of diabetes. Kidney Int. 2017 07; 92(1):14-16. PMID: 28646990.
      View in: PubMed
    6. Long J, Badal SS, Ye Z, Wang Y, Ayanga BA, Galvan DL, Green NH, Chang BH, Overbeek PA, Danesh FR. Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy. J Clin Invest. 2016 11 01; 126(11):4205-4218. PMID: 27760051.
      View in: PubMed
    7. Badal SS, Wang Y, Long J, Corcoran DL, Chang BH, Truong LD, Kanwar YS, Overbeek PA, Danesh FR. miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy. Nat Commun. 2016 06 28; 7:12076. PMID: 27350436.
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    8. Ayanga BA, Badal SS, Wang Y, Galvan DL, Chang BH, Schumacker PT, Danesh FR. Dynamin-Related Protein 1 Deficiency Improves Mitochondrial Fitness and Protects against Progression of Diabetic Nephropathy. J Am Soc Nephrol. 2016 09; 27(9):2733-47. PMID: 26825530.
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    9. Galvan DL, Danesh FR. Paradoxical Role of IL-17 in Progression of Diabetic Nephropathy. J Am Soc Nephrol. 2016 Mar; 27(3):657-8. PMID: 26334029.
      View in: PubMed
    10. Badal SS, Danesh FR. Diabetic Nephropathy: Emerging Biomarkers for Risk Assessment. Diabetes. 2015 Sep; 64(9):3063-5. PMID: 26294427.
      View in: PubMed
    11. Peng H, Cao J, Yu R, Danesh F, Wang Y, Mitch WE, Xu J, Hu Z. CKD Stimulates Muscle Protein Loss Via Rho-associated Protein Kinase 1 Activation. J Am Soc Nephrol. 2016 Feb; 27(2):509-19. PMID: 26054539.
      View in: PubMed
    12. Luo J, Liang M, Mitch WE, Danesh FR, Yu M, Cheng J. FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice. Endocrinology. 2015 Jun; 156(6):2200-10. PMID: 25774552.
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    13. Badal SS, Danesh FR. MicroRNAs and their applications in kidney diseases. Pediatr Nephrol. 2015 May; 30(5):727-40. PMID: 24928414.
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    14. Badal SS, Danesh FR. New insights into molecular mechanisms of diabetic kidney disease. Am J Kidney Dis. 2014 Feb; 63(2 Suppl 2):S63-83. PMID: 24461730.
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    15. Long J, Badal SS, Wang Y, Chang BH, Rodriguez A, Danesh FR. MicroRNA-22 is a master regulator of bone morphogenetic protein-7/6 homeostasis in the kidney. J Biol Chem. 2013 Dec 20; 288(51):36202-14. PMID: 24163368.
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    16. Badal SS, Danesh FR. Strategies to reverse endothelial dysfunction in diabetic nephropathy. Kidney Int. 2012 Dec; 82(11):1151-4. PMID: 23151985.
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    17. Wang W, He B, Shi W, Liang X, Ma J, Shan Z, Hu Z, Danesh FR. Deletion of scavenger receptor A protects mice from progressive nephropathy independent of lipid control during diet-induced hyperlipidemia. Kidney Int. 2012 May; 81(10):1002-1014. PMID: 22377830.
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    18. Wang W, Wang Y, Long J, Wang J, Haudek SB, Overbeek P, Chang BH, Schumacker PT, Danesh FR. Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. Cell Metab. 2012 Feb 08; 15(2):186-200. PMID: 22326220.
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    19. Badal SS, Danesh FR. Managing microvascular complications of diabetes with microRNAs. J Am Soc Nephrol. 2012 Feb; 23(2):185-7. PMID: 22241893.
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    20. Bakota EL, Wang Y, Danesh FR, Hartgerink JD. Injectable multidomain peptide nanofiber hydrogel as a delivery agent for stem cell secretome. Biomacromolecules. 2011 May 09; 12(5):1651-7. PMID: 21417437.
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    21. Wang Y, Bakota E, Chang BH, Entman M, Hartgerink JD, Danesh FR. Peptide nanofibers preconditioned with stem cell secretome are renoprotective. J Am Soc Nephrol. 2011 Apr; 22(4):704-17. PMID: 21415151.
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    22. Long J, Wang Y, Wang W, Chang BH, Danesh FR. MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy. J Biol Chem. 2011 Apr 01; 286(13):11837-48. PMID: 21310958.
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    23. Wang J, Wang Y, Long J, Chang BH, Wilson MH, Overbeek P, Danesh FR. Tamoxifen-inducible podocyte-specific iCre recombinase transgenic mouse provides a simple approach for modulation of podocytes in vivo. Genesis. 2010 Jul; 48(7):446-51. PMID: 20641128.
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    24. Long J, Wang Y, Wang W, Chang BH, Danesh FR. Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions. J Biol Chem. 2010 Jul 23; 285(30):23457-65. PMID: 20501654.
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    25. Sun L, Xie P, Wada J, Kashihara N, Liu FY, Zhao Y, Kumar D, Chugh SS, Danesh FR, Kanwar YS. Rap1b GTPase ameliorates glucose-induced mitochondrial dysfunction. J Am Soc Nephrol. 2008 Dec; 19(12):2293-301. PMID: 18753253.
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    26. Kanwar YS, Wada J, Sun L, Xie P, Wallner EI, Chen S, Chugh S, Danesh FR. Diabetic nephropathy: mechanisms of renal disease progression. Exp Biol Med (Maywood). 2008 Jan; 233(1):4-11. PMID: 18156300.
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    27. Kolavennu V, Zeng L, Peng H, Wang Y, Danesh FR. Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control. Diabetes. 2008 Mar; 57(3):714-23. PMID: 18083785.
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    28. Kanwar YS, Danesh FR, Chugh SS. Chimerism of the renal glomerulus revisited. J Am Soc Nephrol. 2007 Aug; 18(8):2215-7. PMID: 17625114.
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    29. Kanwar YS, Danesh FR, Chugh SS. Contribution of proteoglycans towards the integrated functions of renal glomerular capillaries: a historical perspective. Am J Pathol. 2007 Jul; 171(1):9-13. PMID: 17591948.
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    30. Tramonti G, Xie P, Wallner EI, Danesh FR, Kanwar YS. Expression and functional characteristics of tubular transporters: P-glycoprotein, PEPT1, and PEPT2 in renal mass reduction and diabetes. Am J Physiol Renal Physiol. 2006 Nov; 291(5):F972-80. PMID: 17028260.
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    31. Xu H, Liu P, Liang L, Danesh FR, Yang X, Ye Y, Zhan Z, Yu X, Peng H, Sun L. RhoA-mediated, tumor necrosis factor alpha-induced activation of NF-kappaB in rheumatoid synoviocytes: inhibitory effect of simvastatin. Arthritis Rheum. 2006 Nov; 54(11):3441-51. PMID: 17075836.
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    32. Xu H, Zeng L, Peng H, Chen S, Jones J, Chew TL, Sadeghi MM, Kanwar YS, Danesh FR. HMG-CoA reductase inhibitor simvastatin mitigates VEGF-induced "inside-out" signaling to extracellular matrix by preventing RhoA activation. Am J Physiol Renal Physiol. 2006 Nov; 291(5):F995-1004. PMID: 16774905.
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    33. Nayak B, Xie P, Akagi S, Yang Q, Sun L, Wada J, Thakur A, Danesh FR, Chugh SS, Kanwar YS. Modulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience. Proc Natl Acad Sci U S A. 2005 Dec 13; 102(50):17952-7. PMID: 16330753.
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    34. Kanwar YS, Akagi S, Nayak B, Sun L, Wada J, Xie P, Thakur A, Chugh SS, Danesh FR. Renal-specific oxidoreductase biphasic expression under high glucose ambience during fetal versus neonatal development. Kidney Int. 2005 Oct; 68(4):1670-83. PMID: 16164644.
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    35. Zeng L, Xu H, Chew TL, Eng E, Sadeghi MM, Adler S, Kanwar YS, Danesh FR. HMG CoA reductase inhibition modulates VEGF-induced endothelial cell hyperpermeability by preventing RhoA activation and myosin regulatory light chain phosphorylation. FASEB J. 2005 Nov; 19(13):1845-7. PMID: 16160062.
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    36. Kanwar YS, Akagi S, Sun L, Nayak B, Xie P, Wada J, Chugh SS, Danesh FR. Cell biology of diabetic kidney disease. Nephron Exp Nephrol. 2005; 101(3):e100-10. PMID: 16088221.
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    37. Kanwar YS, Nayak B, Lin S, Akagi S, Xie P, Wada J, Chugh SS, Danesh FR. Hyperglycemia: its imminent effects on mammalian nephrogenesis. Pediatr Nephrol. 2005 Jul; 20(7):858-66. PMID: 15875217.
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    38. Chen S, Lee JS, Iglesias-de la Cruz MC, Wang A, Izquierdo-Lahuerta A, Gandhi NK, Danesh FR, Wolf G, Ziyadeh FN. Angiotensin II stimulates alpha3(IV) collagen production in mouse podocytes via TGF-beta and VEGF signalling: implications for diabetic glomerulopathy. Nephrol Dial Transplant. 2005 Jul; 20(7):1320-8. PMID: 15840669.
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    39. Shah S, Paparello J, Danesh FR. Effects of statin therapy on the progression of chronic kidney disease. Adv Chronic Kidney Dis. 2005 Apr; 12(2):187-95. PMID: 15822054.
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    40. Zeng L, Xu H, Chew TL, Chisholm R, Sadeghi MM, Kanwar YS, Danesh FR. Simvastatin modulates angiotensin II signaling pathway by preventing Rac1-mediated upregulation of p27. J Am Soc Nephrol. 2004 Jul; 15(7):1711-20. PMID: 15213258.
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    41. Danesh FR, Kanwar YS. Modulatory effects of HMG-CoA reductase inhibitors in diabetic microangiopathy. FASEB J. 2004 May; 18(7):805-15. PMID: 15117885.
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    42. Kanwar YS, Wada J, Lin S, Danesh FR, Chugh SS, Yang Q, Banerjee T, Lomasney JW. Update of extracellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis. Am J Physiol Renal Physiol. 2004 Feb; 286(2):F202-15. PMID: 14707006.
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    43. Danesh FR, Wada J, Wallner EI, Sahai A, Srivastava SK, Kanwar YS. Gene regulation of aldose-, aldehyde- and a renal specific oxido reductase (RSOR) in the pathobiology of diabetes mellitus. Curr Med Chem. 2003 Aug; 10(15):1399-406. PMID: 12871137.
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    44. Zeng L, Kanwar YS, Amro N, Phillips C, Molitch M, Batlle D, Danesh FR. Epigenetic and genetic analysis of p16 in dermal fibroblasts from type 1 diabetic patients with nephropathy. Kidney Int. 2003 Jun; 63(6):2094-102. PMID: 12753296.
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    45. Danesh FR, Anel RL, Zeng L, Lomasney J, Sahai A, Kanwar YS. Immunomodulatory effects of HMG-CoA reductase inhibitors. Arch Immunol Ther Exp (Warsz). 2003; 51(3):139-48. PMID: 12894868.
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    46. Lin S, Sahai A, Chugh SS, Pan X, Wallner EI, Danesh FR, Lomasney JW, Kanwar YS. High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway. J Biol Chem. 2002 Nov 01; 277(44):41725-35. PMID: 12196513.
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    47. Danesh FR, Sadeghi MM, Amro N, Philips C, Zeng L, Lin S, Sahai A, Kanwar YS. 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):8301-5. PMID: 12048257.
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    48. Sun L, Pan X, Wada J, Haas CS, Wuthrich RP, Danesh FR, Chugh SS, Kanwar YS. Isolation and functional analysis of mouse UbA52 gene and its relevance to diabetic nephropathy. J Biol Chem. 2002 Aug 16; 277(33):29953-62. PMID: 12171997.
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    49. Danesh FR, Lynch P, Kanwar YS. Lupus membranous glomerulonephritis mimicking hepatitis C-associated nephropathy. Am J Kidney Dis. 2002 Mar; 39(3):E19. PMID: 11877599.
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    50. De Wolf AM, Fragen RJ, Avram MJ, Fitzgerald PC, Rahimi-Danesh F. The pharmacokinetics of dexmedetomidine in volunteers with severe renal impairment. Anesth Analg. 2001 Nov; 93(5):1205-9. PMID: 11682398.
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    51. Danesh F, Ho LT. Dialysis-related amyloidosis: history and clinical manifestations. Semin Dial. 2001 Mar-Apr; 14(2):80-5. PMID: 11264771.
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    52. Danesh FR, Ye M, Salmi S, Lapointe M, Batlle D. Temporal profile of serum-induced S-phase entry and retinoblastoma protein phosphorylation in human skin fibroblasts. Kidney Int. 1999 Oct; 56(4):1282-5. PMID: 10504475.
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    53. Danesh FR, Klinkmann J, Yokoo H, Ivanovich P. Fatal cervical spondyloarthropathy in a hemodialysis patient with systemic deposition of beta2-microglobulin amyloid. Am J Kidney Dis. 1999 Mar; 33(3):563-6. PMID: 10070922.
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    54. Keilani T, Danesh FR, Schlueter WA, Molteni A, Batlle D. A subdepressor low dose of ramipril lowers urinary protein excretion without increasing plasma potassium. Am J Kidney Dis. 1999 Mar; 33(3):450-7. PMID: 10070908.
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    55. Danesh FR, Batlle D. H+-ATPase in hyperkalemic distal renal tubular acidosis. Am J Kidney Dis. 1998 Dec; 32(6):1091-5; discussion 1095-7. PMID: 9856531.
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    56. MiR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy. Nature Communications. 7.
    57. Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy. Journal of Clinical Investigation. 126:4205-4218.
    58. CKD stimulates muscle protein loss via rho-associated protein kinase 1 activation. Journal of the American Society of Nephrology. 27:509-519.
    59. Paradoxical role of IL-17 in progression of diabetic nephropathy. Journal of the American Society of Nephrology. 27:657-658.
    60. Reactive oxygen species and diabetic nephropathy. 2659-2674.
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