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One or more keywords matched the following items that are connected to GOODELL, MARGARET
Item TypeName
Academic Article Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage.
Academic Article Use of CD9 expression to enrich for porcine hematopoietic progenitors.
Academic Article Advancing the fast-paced field of stem cell research: stem cells increases from 6 to 10 issues in its 23rd year of publication.
Academic Article Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration.
Academic Article Transient RNA interference in hematopoietic progenitors with functional consequences.
Academic Article The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging.
Academic Article Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates.
Academic Article Tracing the origin of non-hematopoietic cells using CD45 PCR restriction fragment length polymorphisms.
Academic Article Techniques for the study of adult stem cells: be fruitful and multiply.
Academic Article Adenoviral transduction of mouse hematopoietic stem cells.
Academic Article Cells of the hepatic side population contribute to liver regeneration and can be replenished with bone marrow stem cells.
Academic Article Efficacy of delayed administration of post-chemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics.
Academic Article The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation.
Academic Article Identification and characterization of side population cells in embryonic stem cell cultures.
Academic Article Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival.
Academic Article Primitive adult hematopoietic stem cells can function as osteoblast precursors.
Academic Article Skeletal muscle fiber-specific green autofluorescence: potential for stem cell engraftment artifacts.
Academic Article Mechanisms of hematopoietic stem cell aging.
Academic Article Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.
Academic Article Molecular signatures of proliferation and quiescence in hematopoietic stem cells.
Academic Article A new allele of Lyl1 confirms its important role in hematopoietic stem cell function.
Academic Article CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation.
Academic Article Editorial retraction.
Academic Article Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response.
Academic Article Bridge over troubled stem cells.
Academic Article Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.
Academic Article Plasticity and tissue regenerative potential of bone marrow-derived cells.
Academic Article Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation.
Academic Article Purification of hematopoietic stem cells using the side population.
Academic Article CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells.
Academic Article Pluripotentiality and conditional transgene regulation in human embryonic stem cells expressing insulated tetracycline-ON transactivator.
Academic Article Molecular profiling of hematopoietic stem cells.
Academic Article An argument against a role for Oct4 in somatic stem cells.
Academic Article Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells.
Academic Article Mouse hematopoietic stem cell identification and analysis.
Academic Article Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression.
Academic Article Chk1 haploinsufficiency results in anemia and defective erythropoiesis.
Academic Article Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells.
Academic Article Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection.
Academic Article Inflammatory signals regulate hematopoietic stem cells.
Academic Article Investigating the role of hematopoietic stem and progenitor cells in regulating the osteogenic differentiation of mesenchymal stem cells in vitro.
Academic Article TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs.
Academic Article The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the lymphoblastic leukemia gene, Lyl1 can support leukemia formation.
Academic Article LYL1 degradation by the proteasome is directed by a N-terminal PEST rich site in a phosphorylation-independent manner.
Academic Article Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells.
Academic Article Dnmt3a is essential for hematopoietic stem cell differentiation.
Academic Article The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells.
Academic Article Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing.
Academic Article Direct conversion of skin cells into blood: alchemy or science?
Academic Article The Hematopoietic Expression Viewer: expanding mobile apps as a scientific tool.
Academic Article Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome.
Academic Article Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice.
Academic Article Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors.
Academic Article Hematopoietic stem cell characterization and isolation.
Academic Article Complement-fixing CD45 monoclonal antibodies to facilitate stem cell transplantation in mouse and man.
Academic Article Phenotype and hematopoietic potential of side population cells throughout embryonic development.
Academic Article Altered phenotype and reduced function of muscle-derived hematopoietic stem cells.
Academic Article Isolation and characterization of functional mammary gland stem cells.
Academic Article Realistic prospects for stem cell therapeutics.
Academic Article An in vivo propagated human acute myeloid leukemia expressing ABCA3.
Academic Article Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system.
Academic Article Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners.
Academic Article Circulating hematopoietic stem cells do not efficiently home to bone marrow during homeostasis.
Academic Article Isolation and characterization of side population cells.
Academic Article Roles of Sca-1 in hematopoietic stem/progenitor cell function.
Academic Article Hematopoietic stem cells do not engraft with absolute efficiencies.
Academic Article Differential mRNA processing in hematopoietic stem cells.
Academic Article Evidence for diversity in transcriptional profiles of single hematopoietic stem cells.
Academic Article Bringing cardiovascular cell-based therapy to clinical application: perspectives based on a National Heart, Lung, and Blood Institute Cell Therapy Working Group meeting.
Academic Article Hematopoietic fingerprints: an expression database of stem cells and their progeny.
Academic Article Stem cell identification and sorting using the Hoechst 33342 side population (SP).
Academic Article Enhanced generation of myeloid lineages in hematopoietic differentiation from embryonic stem cells by silencing transcriptional repressor Twist-2.
Academic Article Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling.
Academic Article CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway.
Academic Article Flow cytometry analysis of murine hematopoietic stem cells.
Academic Article The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors.
Academic Article Isolation and characterization of mouse side population cells.
Academic Article Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery.
Concept Precursor Cell Lymphoblastic Leukemia-Lymphoma
Concept Jurkat Cells
Concept Cell Movement
Concept Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Concept Hematopoietic Stem Cells
Concept Cell Nucleolus
Concept Satellite Cells, Skeletal Muscle
Concept Cell Fusion
Concept Cell Lineage
Concept Erythroid Precursor Cells
Concept Hematopoietic Stem Cell Transplantation
Concept Cell Nucleus
Concept Cell Division
Concept COS Cells
Concept Resting Phase, Cell Cycle
Concept Blood Cell Count
Concept Cell Cycle Proteins
Concept Cell Cycle
Concept Cell Culture Techniques
Concept Clone Cells
Concept Myeloid Progenitor Cells
Concept K562 Cells
Concept Cell Transformation, Neoplastic
Concept Receptors, Cell Surface
Concept Cell Survival
Concept Germ Cells
Concept Blood Cells
Concept Stem Cell Transplantation
Concept Antigen-Presenting Cells
Concept Muscle Cells
Concept Embryonic Stem Cells
Concept Cell Line
Concept Tumor Stem Cell Assay
Concept Adult Stem Cells
Concept Multipotent Stem Cells
Concept Hematopoietic Stem Cell Mobilization
Concept Cell Differentiation
Concept Lymphoid Progenitor Cells
Concept Bone Marrow Cells
Concept Pluripotent Stem Cells
Concept Cell Transplantation
Concept Erythroid Cells
Concept Leukemia, Lymphocytic, Chronic, B-Cell
Concept Myeloid Cells
Concept Cell Line, Tumor
Concept Cells, Cultured
Concept Stem Cells
Concept Cell Separation
Concept Cell Proliferation
Concept Cell Count
Concept Stem Cell Niche
Academic Article Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells.
Academic Article Parental permissions: H19 and keeping the stem cell progeny under control.
Academic Article A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells.
Academic Article Large conserved domains of low DNA methylation maintained by Dnmt3a.
Academic Article Hematopoietic stem cell development: an epigenetic journey.
Academic Article Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal.
Academic Article mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).
Academic Article A gallon of sweat to make a pint of blood.
Academic Article Rising from the crypt: decreasing DNA methylation during differentiation of the small intestine.
Academic Article New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells.
Academic Article Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells.
Academic Article Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.
Academic Article Dynamic DNA methylation discovered during HSC differentiation.
Academic Article Introduction to a review series on hematopoietic stem cells.
Academic Article Long non-coding RNAs control hematopoietic stem cell function.
Academic Article Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments.
Academic Article Comparative long-term effects of interferon a and hydroxyurea on human hematopoietic progenitor cells.
Academic Article Stem Cells and Aging: What's Next?
Academic Article Acute loss of TET function results in aggressive myeloid cancer in mice.
Academic Article Stem cells and healthy aging.
Academic Article DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
Academic Article DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
Academic Article DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells.
Academic Article DNMT3A in Leukemia.
Academic Article Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.
Academic Article DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
Academic Article Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein.
Academic Article DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A.
Academic Article Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.
Academic Article Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In?Vivo.
Academic Article Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.
Academic Article Genome-Wide Analysis of DNA Methylation in Hematopoietic Cells: DNA Methylation Analysis by WGBS.
Academic Article DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells.
Academic Article Mutant NPM1 Maintains the Leukemic State through HOX Expression.
Academic Article DNA methylation and de-methylation using hybrid site-targeting proteins.
Academic Article PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Academic Article New insights into the biology of acute myeloid leukemia with mutated NPM1.
Grant CD34 NEGATIVE HUMAN HEMATOPOIETIC STEM CELLS
Grant REGULATION OF HEMATOPOIETIC PROGENITORS BY DE NOVO DNA METHYLATION
Grant BD LSRII Four Laser Analytical Flow Cytometer
Grant CD34NEGATIVE HUMAN HEMATOPOIETIC STEM CELLS
Grant Regulatory Networks in Human Embryonic Stem Cells
Grant Cell Fate Tracking in the Aging Hematopoietic System
Grant Conference on Molecular Regulation of Stem Cells
Grant DNMT3A in Development of Hematologic Malignancies
Grant Hematology Training Program
Grant Hematopoietic Stem Cell Differentiation and Commitment
Grant Regulation of Hematopoietic Progenitors by de novo DNA Methylation
Academic Article Single-cell technology meets hematology: introduction to a review series.
Academic Article Measure Twice, Cut Once: Therapeutic Editing of HSPCs Requires Precise Planning.
Concept Mouse Embryonic Stem Cells
Concept Cell Self Renewal
Concept T-Cell Acute Lymphocytic Leukemia Protein 1
Concept HEK293 Cells
Concept Side-Population Cells
Concept Single-Cell Analysis
Concept Cell Cycle Checkpoints
Concept MCF-7 Cells
Grant Clonal Hematopoiesis, Aging and Genome Stability in PPM1D Mutants
Academic Article Environmental influences on clonal hematopoiesis.
Academic Article Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis.
Academic Article WIP1 dephosphorylation of p27Kip1 Serine 140 destabilizes p27Kip1 and reverses anti-proliferative effects of ATM phosphorylation.
Academic Article A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells.
Academic Article It's All About MEis: Menin-MLL Inhibition Eradicates NPM1-Mutated and MLL-Rearranged Acute Leukemias in Mice.
Academic Article Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity.
Academic Article Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
Academic Article Clonal hematopoiesis: mechanisms driving dominance of stem cell clones.
Academic Article Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice.
Academic Article Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome.
Academic Article Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL.
Academic Article Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor.
Academic Article Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities.
Academic Article PPM1D in Solid and Hematologic Malignancies: Friend and Foe?
Academic Article Ageing and rejuvenation of tissue stem cells and their niches.
Academic Article First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein-Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation.
Academic Article Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain.
Academic Article DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells.
Academic Article Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging.
Academic Article SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells.
Academic Article SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
Academic Article TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells.
Academic Article SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
Academic Article Tissue mosaicism following stem cell aging: blood as an exemplar.
Academic Article Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing.
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