Item Type | Name |
Academic Article
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Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage.
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Academic Article
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Use of CD9 expression to enrich for porcine hematopoietic progenitors.
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Academic Article
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Advancing the fast-paced field of stem cell research: stem cells increases from 6 to 10 issues in its 23rd year of publication.
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Academic Article
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Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration.
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Academic Article
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Transient RNA interference in hematopoietic progenitors with functional consequences.
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Academic Article
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The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging.
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Academic Article
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Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates.
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Academic Article
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Tracing the origin of non-hematopoietic cells using CD45 PCR restriction fragment length polymorphisms.
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Academic Article
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Techniques for the study of adult stem cells: be fruitful and multiply.
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Academic Article
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Adenoviral transduction of mouse hematopoietic stem cells.
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Academic Article
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Cells of the hepatic side population contribute to liver regeneration and can be replenished with bone marrow stem cells.
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Academic Article
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Efficacy of delayed administration of post-chemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics.
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Academic Article
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The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation.
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Academic Article
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Identification and characterization of side population cells in embryonic stem cell cultures.
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Academic Article
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Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival.
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Academic Article
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Primitive adult hematopoietic stem cells can function as osteoblast precursors.
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Academic Article
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Skeletal muscle fiber-specific green autofluorescence: potential for stem cell engraftment artifacts.
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Academic Article
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Mechanisms of hematopoietic stem cell aging.
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Academic Article
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Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.
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Academic Article
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Molecular signatures of proliferation and quiescence in hematopoietic stem cells.
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Academic Article
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A new allele of Lyl1 confirms its important role in hematopoietic stem cell function.
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Academic Article
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CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation.
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Academic Article
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Editorial retraction.
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Academic Article
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Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response.
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Academic Article
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Bridge over troubled stem cells.
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Academic Article
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Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways.
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Academic Article
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Plasticity and tissue regenerative potential of bone marrow-derived cells.
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Academic Article
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Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation.
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Academic Article
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Purification of hematopoietic stem cells using the side population.
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Academic Article
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CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells.
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Academic Article
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Pluripotentiality and conditional transgene regulation in human embryonic stem cells expressing insulated tetracycline-ON transactivator.
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Academic Article
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Molecular profiling of hematopoietic stem cells.
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Academic Article
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An argument against a role for Oct4 in somatic stem cells.
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Academic Article
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Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells.
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Academic Article
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Mouse hematopoietic stem cell identification and analysis.
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Academic Article
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Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression.
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Academic Article
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Chk1 haploinsufficiency results in anemia and defective erythropoiesis.
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Academic Article
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Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells.
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Academic Article
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Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection.
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Academic Article
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Inflammatory signals regulate hematopoietic stem cells.
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Academic Article
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Investigating the role of hematopoietic stem and progenitor cells in regulating the osteogenic differentiation of mesenchymal stem cells in vitro.
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Academic Article
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TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs.
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Academic Article
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The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the lymphoblastic leukemia gene, Lyl1 can support leukemia formation.
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Academic Article
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LYL1 degradation by the proteasome is directed by a N-terminal PEST rich site in a phosphorylation-independent manner.
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Academic Article
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Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells.
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Academic Article
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Dnmt3a is essential for hematopoietic stem cell differentiation.
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Academic Article
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The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells.
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Academic Article
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Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing.
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Academic Article
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Direct conversion of skin cells into blood: alchemy or science?
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Academic Article
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The Hematopoietic Expression Viewer: expanding mobile apps as a scientific tool.
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Academic Article
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Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome.
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Academic Article
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Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice.
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Academic Article
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Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors.
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Academic Article
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Hematopoietic stem cell characterization and isolation.
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Academic Article
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Complement-fixing CD45 monoclonal antibodies to facilitate stem cell transplantation in mouse and man.
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Academic Article
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Phenotype and hematopoietic potential of side population cells throughout embryonic development.
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Academic Article
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Altered phenotype and reduced function of muscle-derived hematopoietic stem cells.
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Academic Article
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Isolation and characterization of functional mammary gland stem cells.
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Academic Article
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Realistic prospects for stem cell therapeutics.
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Academic Article
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An in vivo propagated human acute myeloid leukemia expressing ABCA3.
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Academic Article
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Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system.
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Academic Article
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Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners.
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Academic Article
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Circulating hematopoietic stem cells do not efficiently home to bone marrow during homeostasis.
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Academic Article
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Isolation and characterization of side population cells.
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Academic Article
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Roles of Sca-1 in hematopoietic stem/progenitor cell function.
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Academic Article
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Hematopoietic stem cells do not engraft with absolute efficiencies.
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Academic Article
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Differential mRNA processing in hematopoietic stem cells.
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Academic Article
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Evidence for diversity in transcriptional profiles of single hematopoietic stem cells.
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Academic Article
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Bringing cardiovascular cell-based therapy to clinical application: perspectives based on a National Heart, Lung, and Blood Institute Cell Therapy Working Group meeting.
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Academic Article
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Hematopoietic fingerprints: an expression database of stem cells and their progeny.
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Academic Article
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Stem cell identification and sorting using the Hoechst 33342 side population (SP).
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Academic Article
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Enhanced generation of myeloid lineages in hematopoietic differentiation from embryonic stem cells by silencing transcriptional repressor Twist-2.
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Academic Article
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Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling.
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Academic Article
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CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway.
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Academic Article
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Flow cytometry analysis of murine hematopoietic stem cells.
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Academic Article
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The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors.
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Academic Article
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Isolation and characterization of mouse side population cells.
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Academic Article
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Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery.
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Concept
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Precursor Cell Lymphoblastic Leukemia-Lymphoma
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Concept
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Jurkat Cells
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Concept
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Cell Movement
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Concept
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Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
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Concept
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Hematopoietic Stem Cells
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Concept
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Cell Nucleolus
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Concept
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Satellite Cells, Skeletal Muscle
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Concept
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Cell Fusion
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Concept
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Cell Lineage
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Concept
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Erythroid Precursor Cells
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Concept
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Hematopoietic Stem Cell Transplantation
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Concept
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Cell Nucleus
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Concept
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Cell Division
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Concept
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COS Cells
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Concept
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Resting Phase, Cell Cycle
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Concept
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Blood Cell Count
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Concept
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Cell Cycle Proteins
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Concept
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Cell Cycle
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Concept
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Cell Culture Techniques
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Concept
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Clone Cells
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Concept
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Myeloid Progenitor Cells
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Concept
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K562 Cells
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Concept
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Cell Transformation, Neoplastic
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Concept
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Receptors, Cell Surface
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Concept
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Cell Survival
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Concept
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Germ Cells
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Concept
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Blood Cells
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Concept
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Stem Cell Transplantation
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Concept
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Antigen-Presenting Cells
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Concept
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Muscle Cells
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Concept
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Embryonic Stem Cells
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Concept
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Cell Line
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Concept
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Tumor Stem Cell Assay
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Concept
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Adult Stem Cells
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Concept
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Multipotent Stem Cells
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Concept
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Hematopoietic Stem Cell Mobilization
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Concept
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Cell Differentiation
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Concept
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Lymphoid Progenitor Cells
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Concept
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Bone Marrow Cells
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Concept
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Pluripotent Stem Cells
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Concept
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Cell Transplantation
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Concept
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Erythroid Cells
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Concept
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Leukemia, Lymphocytic, Chronic, B-Cell
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Concept
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Myeloid Cells
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Concept
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Cell Line, Tumor
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Concept
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Cells, Cultured
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Concept
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Stem Cells
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Concept
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Cell Separation
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Concept
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Cell Proliferation
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Concept
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Cell Count
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Concept
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Stem Cell Niche
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Academic Article
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Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells.
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Academic Article
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Parental permissions: H19 and keeping the stem cell progeny under control.
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Academic Article
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A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells.
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Academic Article
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Large conserved domains of low DNA methylation maintained by Dnmt3a.
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Academic Article
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Hematopoietic stem cell development: an epigenetic journey.
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Academic Article
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Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal.
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Academic Article
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mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).
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Academic Article
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A gallon of sweat to make a pint of blood.
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Academic Article
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Rising from the crypt: decreasing DNA methylation during differentiation of the small intestine.
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Academic Article
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New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells.
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Academic Article
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Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells.
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Academic Article
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Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.
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Academic Article
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Dynamic DNA methylation discovered during HSC differentiation.
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Academic Article
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Introduction to a review series on hematopoietic stem cells.
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Academic Article
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Long non-coding RNAs control hematopoietic stem cell function.
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Academic Article
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Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments.
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Academic Article
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Comparative long-term effects of interferon a and hydroxyurea on human hematopoietic progenitor cells.
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Academic Article
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Stem Cells and Aging: What's Next?
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Academic Article
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Acute loss of TET function results in aggressive myeloid cancer in mice.
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Academic Article
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Stem cells and healthy aging.
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Academic Article
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DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
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Academic Article
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DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia.
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Academic Article
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DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells.
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Academic Article
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DNMT3A in Leukemia.
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Academic Article
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Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.
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Academic Article
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DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.
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Academic Article
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Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein.
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Academic Article
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DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A.
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Academic Article
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Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.
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Academic Article
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Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In?Vivo.
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Academic Article
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Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.
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Academic Article
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Genome-Wide Analysis of DNA Methylation in Hematopoietic Cells: DNA Methylation Analysis by WGBS.
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Academic Article
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DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells.
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Academic Article
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Mutant NPM1 Maintains the Leukemic State through HOX Expression.
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Academic Article
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DNA methylation and de-methylation using hybrid site-targeting proteins.
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Academic Article
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PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
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Academic Article
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New insights into the biology of acute myeloid leukemia with mutated NPM1.
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Grant
|
CD34 NEGATIVE HUMAN HEMATOPOIETIC STEM CELLS
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Grant
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REGULATION OF HEMATOPOIETIC PROGENITORS BY DE NOVO DNA METHYLATION
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Grant
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BD LSRII Four Laser Analytical Flow Cytometer
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Grant
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CD34NEGATIVE HUMAN HEMATOPOIETIC STEM CELLS
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Grant
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Regulatory Networks in Human Embryonic Stem Cells
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Grant
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Cell Fate Tracking in the Aging Hematopoietic System
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Grant
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Conference on Molecular Regulation of Stem Cells
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Grant
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DNMT3A in Development of Hematologic Malignancies
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Grant
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Hematology Training Program
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Grant
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Hematopoietic Stem Cell Differentiation and Commitment
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Grant
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Regulation of Hematopoietic Progenitors by de novo DNA Methylation
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Academic Article
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Single-cell technology meets hematology: introduction to a review series.
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Academic Article
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Measure Twice, Cut Once: Therapeutic Editing of HSPCs Requires Precise Planning.
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Concept
|
Mouse Embryonic Stem Cells
|
Concept
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Cell Self Renewal
|
Concept
|
T-Cell Acute Lymphocytic Leukemia Protein 1
|
Concept
|
HEK293 Cells
|
Concept
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Side-Population Cells
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Concept
|
Single-Cell Analysis
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Concept
|
Cell Cycle Checkpoints
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Concept
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MCF-7 Cells
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Grant
|
Clonal Hematopoiesis, Aging and Genome Stability in PPM1D Mutants
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Academic Article
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Environmental influences on clonal hematopoiesis.
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Academic Article
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Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis.
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Academic Article
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WIP1 dephosphorylation of p27Kip1 Serine 140 destabilizes p27Kip1 and reverses anti-proliferative effects of ATM phosphorylation.
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Academic Article
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A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells.
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Academic Article
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It's All About MEis: Menin-MLL Inhibition Eradicates NPM1-Mutated and MLL-Rearranged Acute Leukemias in Mice.
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Academic Article
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Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity.
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Academic Article
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Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion.
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Academic Article
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Clonal hematopoiesis: mechanisms driving dominance of stem cell clones.
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Academic Article
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Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice.
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Academic Article
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Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome.
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Academic Article
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Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL.
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Academic Article
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Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor.
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Academic Article
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Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities.
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Academic Article
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PPM1D in Solid and Hematologic Malignancies: Friend and Foe?
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Academic Article
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Ageing and rejuvenation of tissue stem cells and their niches.
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Academic Article
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First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein-Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation.
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Academic Article
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Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain.
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Academic Article
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DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells.
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Academic Article
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Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging.
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Academic Article
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SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells.
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Academic Article
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SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
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Academic Article
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TET2 modulates spatial relocalization of heterochromatin in aged hematopoietic stem and progenitor cells.
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Academic Article
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SRCAP mutations drive clonal hematopoiesis through epigenetic and DNA repair dysregulation.
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Academic Article
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Tissue mosaicism following stem cell aging: blood as an exemplar.
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Academic Article
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Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing.
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