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GARCIA-MANERO, GUILLERMO

One or more keywords matched the following items that are connected to GARCIA-MANERO, GUILLERMO

Item Type	Name
Concept	Chromosomal Proteins, Non-Histone
Concept	Histone Deacetylase Inhibitors
Concept	Histone Deacetylase 1
Concept	Jumonji Domain-Containing Histone Demethylases
Concept	Histone Deacetylases
Concept	Histones
Concept	Histone-Lysine N-Methyltransferase
Academic Article	Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound ?-phenylethyl isothiocyanate.
Academic Article	Histone deacetylase inhibitors: a review of their clinical status as antineoplastic agents.
Academic Article	Use of hypomethylating agents in myelodysplastic syndromes.
Academic Article	Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia.
Academic Article	RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression.
Academic Article	Preclinical antileukemia activity of JNJ-26481585, a potent second-generation histone deacetylase inhibitor.
Academic Article	Trisomy 11 in myelodysplastic syndromes defines a unique group of disease with aggressive clinicopathologic features.
Academic Article	Characteristics of pericardial effusions in patients with leukemia.
Academic Article	Acute myeloid leukemia with t(9;11)(p21-22;q23): common properties of dysregulated ras pathway signaling and genomic progression characterize de novo and therapy-related cases.
Academic Article	A phase I study of vorinostat in combination with idarubicin in relapsed or refractory leukaemia.
Academic Article	The combination of a histone deacetylase inhibitor with the Bcl-2 homology domain-3 mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy.
Academic Article	Myelodysplastic syndromes with deletions of chromosome 11q lack cryptic MLL rearrangement and exhibit characteristic clinicopathologic features.
Academic Article	Histone deacetylase inhibitors for the treatment of myelodysplastic syndrome and acute myeloid leukemia.
Academic Article	Treatment of higher-risk myelodysplastic syndrome.
Academic Article	Low frequency of H3.3 mutations and upregulated DAXX expression in MDS.
Academic Article	Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes.
Academic Article	Role of epigenetic therapy in myelodysplastic syndrome.
Academic Article	Histone methylation in myelodysplastic syndromes.
Academic Article	Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells.
Academic Article	Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia.
Academic Article	Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome.
Academic Article	Epigenetic therapy of leukemia: An update.
Academic Article	Current and future management options for myelodysplastic syndromes.
Academic Article	The combination of a histone deacetylase inhibitor with the BH3-mimetic GX15-070 has synergistic antileukemia activity by activating both apoptosis and autophagy.
Academic Article	Phase II study of the histone deacetylase inhibitor panobinostat (LBH589) in patients with low or intermediate-1 risk myelodysplastic syndrome.
Academic Article	Can we improve outcomes in patients with acute myelogenous leukemia? Incorporating HDAC inhibitors into front-line therapy.
Academic Article	Toll-like receptor alterations in myelodysplastic syndrome.
Academic Article	Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor.
Academic Article	A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies.
Academic Article	Mocetinostat (MGCD0103): a review of an isotype-specific histone deacetylase inhibitor.
Academic Article	Epigenetic inactivation of Notch-Hes pathway in human B-cell acute lymphoblastic leukemia.
Academic Article	Future directions for the use of hypomethylating agents.
Academic Article	Phase I study of anti-VEGF monoclonal antibody bevacizumab and histone deacetylase inhibitor valproic acid in patients with advanced cancers.
Academic Article	HDAC inhibitors repress BARD1 isoform expression in acute myeloid leukemia cells via activation of miR-19a and/or b.
Academic Article	Deacetylase inhibitors for the treatment of myelodysplastic syndromes.
Academic Article	Novel drugs for older patients with acute myeloid leukemia.
Academic Article	Results of phase 2 randomized study of low-dose decitabine with or without valproic acid in patients with myelodysplastic syndrome and acute myelogenous leukemia.
Academic Article	Analysis of class I and II histone deacetylase gene expression in human leukemia.
Academic Article	Quantitative proteomic analysis of histone modifications in decitabine sensitive and resistant leukemia cell lines.
Academic Article	Quantitative proteomic analysis of histone modifications in decitabine sensitive and resistant leukemia cell lines
Academic Article	Analysis of class i and II histone deacetylase gene expression in human leukemia
Academic Article	Down-regulation of EZH2 expression in myelodysplastic syndromes.
Academic Article	c-Myc Modulation and Acetylation Is a Key HDAC Inhibitor Target in Cancer.
Academic Article	KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice.
Academic Article	The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia.
Academic Article	A phase II study of addition of pracinostat to a hypomethylating agent in patients with myelodysplastic syndromes who have not responded to previous hypomethylating agent therapy.
Academic Article	The early achievement of measurable residual disease negativity in the treatment of adults with Philadelphia-negative B-cell acute lymphoblastic leukemia is a strong predictor for survival.
Academic Article	t(11;16)(q23;p13)/KMT2A-CREBBP in hematologic malignancies: presumptive evidence of myelodysplasia or therapy-related neoplasm?
Academic Article	Myelodysplastic syndrome with t(6;9)(p22;q34.1)/DEK-NUP214 better classified as acute myeloid leukemia? A multicenter study of 107 cases.
Academic Article	Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements.
Academic Article	Cooperation between KDM6B overexpression and TET2 deficiency in the pathogenesis of chronic myelomonocytic leukemia.

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Histones