| Item Type | Name |
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Academic Article
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Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses.
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Academic Article
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Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes.
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Academic Article
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Ex vivo expanded umbilical cord blood T cells maintain naive phenotype and TCR diversity.
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Academic Article
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Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.
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Academic Article
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Lovastatin inhibits T-cell proliferation while preserving the cytolytic function of EBV, CMV, and MART-1-specific CTLs.
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Academic Article
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Generation of functional CLL-specific cord blood CTL using CD40-ligated CLL APC.
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Academic Article
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Immunotherapy of hematologic malignancy.
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Academic Article
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Assembly of the kappa preB receptor requires a V kappa-like protein encoded by a germline transcript.
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Academic Article
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In vivo expansion of LMP 1- and 2-specific T-cells in a patient who received donor-derived EBV-specific T-cells after allogeneic stem cell transplantation.
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Academic Article
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Risk factors associated with late cytomegalovirus reactivation after allogeneic stem cell transplantation for hematological malignancies.
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Concept
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Antigens, Differentiation, T-Lymphocyte
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Concept
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Gene Rearrangement, T-Lymphocyte
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Concept
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Lymphocytes
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Concept
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T-Lymphocytes, Cytotoxic
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Concept
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Lymphocyte Function-Associated Antigen-1
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Concept
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T-Lymphocytes, Helper-Inducer
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Concept
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Lymphocyte Activation
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Concept
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Lymphocyte Depletion
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Concept
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CD8-Positive T-Lymphocytes
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Concept
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Lymphocyte Count
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Concept
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B-Lymphocyte Subsets
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Concept
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CD4 Lymphocyte Count
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Concept
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T-Lymphocytes, Regulatory
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Concept
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CD4-Positive T-Lymphocytes
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Concept
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B-Lymphocytes
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Concept
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T-Lymphocyte Subsets
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Concept
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Epitopes, T-Lymphocyte
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Concept
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Lymphocytes, Tumor-Infiltrating
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Concept
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T-Lymphocytes
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Concept
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Lymphocyte Culture Test, Mixed
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Concept
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Lymphocyte Transfusion
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Academic Article
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Third-party umbilical cord blood-derived regulatory T cells prevent xenogenic graft-versus-host disease.
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Academic Article
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Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD.
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Academic Article
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CD34+ cell dose predicts survival, posttransplant morbidity, and rate of hematologic recovery after allogeneic marrow transplants for hematologic malignancies.
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Academic Article
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Antithymocyte globulin for patients with myelodysplastic syndrome.
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Academic Article
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Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor Vbeta profiles.
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Academic Article
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CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans.
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Academic Article
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Vaccination for leukemia.
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Academic Article
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PR1-specific T cells are associated with unmaintained cytogenetic remission of chronic myelogenous leukemia after interferon withdrawal.
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Academic Article
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Adoptive transfer of PR1 cytotoxic T lymphocytes associated with reduced leukemia burden in a mouse acute myeloid leukemia xenograft model.
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Academic Article
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Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic mice.
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Academic Article
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Targeting human B-cell malignancies through Ig light chain-specific cytotoxic T lymphocytes.
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Academic Article
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What T cells see in WT-1.
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Academic Article
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Alloreactive CD4+ T lymphocytes can exert cytotoxicity to chronic myeloid leukaemia cells processing and presenting exogenous antigen.
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Academic Article
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Targeted T-cell therapy for human leukemia: cytotoxic T lymphocytes specific for a peptide derived from proteinase 3 preferentially lyse human myeloid leukemia cells.
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Academic Article
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Immune escape from a graft-versus-leukemia effect may play a role in the relapse of myeloid leukemias following allogeneic bone marrow transplantation.
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Academic Article
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Cytotoxic T lymphocytes specific for a nonpolymorphic proteinase 3 peptide preferentially inhibit chronic myeloid leukemia colony-forming units.
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Academic Article
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T cell-depleted bone marrow transplantation and delayed T cell add-back to control acute GVHD and conserve a graft-versus-leukemia effect.
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Academic Article
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Donor-recipient polymorphism of the proteinase 3 gene: a potential target for T-cell alloresponses to myeloid leukemia.
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Academic Article
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Reinventing bone marrow transplantation: reducing toxicity using nonmyeloablative, preparative regimens and induction of graft-versus-malignancy.
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Academic Article
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A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia.
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Academic Article
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Harnessing graft-versus-malignancy: non-myeloablative preparative regimens for allogeneic haematopoietic transplantation, an evolving strategy for adoptive immunotherapy.
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Academic Article
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The basis of T-cell-mediated immunity to chronic myelogenous leukemia.
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Academic Article
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Chronic myelogenous leukemia shapes host immunity by selective deletion of high-avidity leukemia-specific T cells.
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Academic Article
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T-large granular lymphocyte lymphoproliferative disorder: expression of CD26 as a marker of clinically aggressive disease and characterization of marrow inhibition.
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Academic Article
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HLA-DR4 predicts haematological response to cyclosporine in T-large granular lymphocyte lymphoproliferative disorders.
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Academic Article
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Immune-induced cytopenia: bone marrow failure syndrome.
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Academic Article
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Functional assessment and specific depletion of alloreactive human T cells using flow cytometry.
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Academic Article
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Hookworm infection of sigmoid colon masquerading as graft-versus-host disease in an allogeneic stem cell transplant recipient after donor lymphocyte infusion for refractory acute promyelocytic leukemia.
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Academic Article
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Delayed immune reconstitution after cord blood transplantation is characterized by impaired thymopoiesis and late memory T-cell skewing.
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Academic Article
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Understanding and enhancing the graft-versus-leukemia effect after hematopoietic stem cell transplantation.
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Academic Article
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Immunotherapy of AML.
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Academic Article
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2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1.
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Academic Article
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Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy.
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Academic Article
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T cell-depleted granulocyte colony-stimulating factor (G-CSF) modified allogenic bone marrow transplantation for hematological malignancy improves graft CD34+ cell content but is associated with delayed pancytopenia.
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Academic Article
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A technique for dual determination of cytotoxic and helper lymphocyte precursor frequency by a miniaturized dye release method.
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Academic Article
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Myelodysplastic syndrome and aplastic anemia: distinct entities or diseases linked by a common pathophysiology?
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Academic Article
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Coincident myelodysplastic syndrome and T-cell large granular lymphocytic disease: clinical and pathophysiological features.
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Academic Article
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Vaccinating transplant recipients.
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Academic Article
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LFA-1 affinity regulation is necessary for the activation and proliferation of naive T cells.
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Academic Article
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Blocking LFA-1 activation with lovastatin prevents graft-versus-host disease in mouse bone marrow transplantation.
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Academic Article
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Cyclic neutropenia associated with T cell immunity to granulocyte proteases and a double de novo mutation in GFI1, a transcriptional regulator of ELANE.
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Academic Article
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Detection and characterization of a novel subset of CD8?CD57? T cells in metastatic melanoma with an incompletely differentiated phenotype.
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Academic Article
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The role of antigen cross-presentation from leukemia blasts on immunity to the leukemia-associated antigen PR1.
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Academic Article
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Vitamin D receptor upregulation in alloreactive human T cells.
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Academic Article
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A novel HLA-A*0201 restricted peptide derived from cathepsin G is an effective immunotherapeutic target in acute myeloid leukemia.
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Academic Article
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Co-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy.
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Academic Article
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Preferential usage of T cell receptor (TCR) V beta by allogeneic T cells recognizing myeloid leukemia cells: implications for separating graft-versus-leukemia effect from graft-versus-host disease.
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Academic Article
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Specific depletion of alloreactive T cells in HLA-identical siblings: a method for separating graft-versus-host and graft-versus-leukaemia reactions.
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Academic Article
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T-cell large granular lymphocyte leukemia is characterized by massive TCRBV-restricted clonal CD8 expansion and a generalized overexpression of the effector cell marker CD57.
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Academic Article
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A novel strategy for rapid and efficient isolation of human tumor-specific CD4(+) and CD8(+) T-cell clones.
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Academic Article
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LFA-1 regulates CD8+ T cell activation via T cell receptor-mediated and LFA-1-mediated Erk1/2 signal pathways.
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Academic Article
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Chemokine receptor CCR5 mediates alloimmune responses in graft-versus-host disease.
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Academic Article
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Common minor histocompatibility antigen discovery based upon patient clinical outcomes and genomic data.
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Academic Article
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Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia.
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Academic Article
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A GVHD kill switch helps immune reconstitution.
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Academic Article
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PR1-specific cytotoxic T lymphocytes are relatively frequent in umbilical cord blood and can be effectively expanded to target myeloid leukemia.
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Academic Article
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PR1-specific cytotoxic T lymphocytes are relatively frequent in umbilical cord blood and can be effectively expanded to target myeloid leukemia
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Academic Article
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PR1 peptide vaccine induces specific immunity with clinical responses in myeloid malignancies.
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Academic Article
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Neutrophil elastase enhances antigen presentation by upregulating human leukocyte antigen class I expression on tumor cells.
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Academic Article
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A novel TCR-like CAR with specificity for PR1/HLA-A2 effectively targets myeloid leukemia in vitro when expressed in human adult peripheral blood and cord blood T cells.
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Academic Article
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Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells.
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Academic Article
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Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells.
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Academic Article
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Trastuzumab Increases HER2 Uptake and Cross-Presentation by Dendritic Cells.
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Academic Article
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Targeting the Leukemia Antigen PR1 with Immunotherapy for the Treatment of Multiple Myeloma.
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Academic Article
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Rapid ex vivo expansion of highly enriched human invariant natural killer T cells via single antigenic stimulation for cell therapy to prevent graft-versus-host disease.
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Academic Article
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Membrane-Associated Proteinase 3 on Granulocytes and Acute Myeloid Leukemia Inhibits T Cell Proliferation.
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Academic Article
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Fucosylation Enhances the Efficacy of Adoptively Transferred Antigen-Specific Cytotoxic T Lymphocytes.
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Academic Article
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Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity.
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Academic Article
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Hypomethylating agent alters the immune microenvironment in acute myeloid leukaemia (AML) and enhances the immunogenicity of a dendritic cell/AML vaccine.
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Academic Article
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A Novel T-Cell Engaging Bi-specific Antibody Targeting the Leukemia Antigen PR1/HLA-A2.
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Concept
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B-Lymphocytes, Regulatory
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Academic Article
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Two unique HLA-A*0201 restricted peptides derived from cyclin E as immunotherapeutic targets in leukemia.
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Academic Article
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Third-Party BK Virus-Specific Cytotoxic T Lymphocyte Therapy for Hemorrhagic Cystitis Following Allotransplantation.
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Academic Article
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Novel myeloperoxidase-derived HLA-A2-restricted peptides as therapeutic targets against myeloid leukemia.
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Academic Article
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Multi-faceted role of LRP1 in the immune system.
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