Lymphocyte Culture Test, Mixed
"Lymphocyte Culture Test, Mixed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
| Descriptor ID |
D007959
|
| MeSH Number(s) |
E01.370.225.812.385.475 E05.200.812.385.475 E05.478.594.385.429
|
| Concept/Terms |
Lymphocyte Culture Test, Mixed- Lymphocyte Culture Test, Mixed
- Leukocyte Culture Test, Mixed
- Mixed Lymphocyte Reaction
- Lymphocyte Reaction, Mixed
- Lymphocyte Reactions, Mixed
- Mixed Lymphocyte Reactions
- Mixed Leukocyte Reaction
- Leukocyte Reaction, Mixed
- Leukocyte Reactions, Mixed
- Mixed Leukocyte Reactions
- Mixed Leukocyte Culture Test
- Mixed Lymphocyte Culture Test
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Culture Test, Mixed".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Culture Test, Mixed".
This graph shows the total number of publications written about "Lymphocyte Culture Test, Mixed" by people in this website by year, and whether "Lymphocyte Culture Test, Mixed" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 2 | 1 | 3 |
| 1998 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 5 | 5 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lymphocyte Culture Test, Mixed" by people in Profiles.
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Microbial metabolite sensor GPR43 controls severity of experimental GVHD. Nat Commun. 2018 09 10; 9(1):3674.
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FOXP3 is a direct target of miR15a/16 in umbilical cord blood regulatory T cells. Bone Marrow Transplant. 2014 Jun; 49(6):793-9.
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Aldehyde dehydrogenase expression drives human regulatory T cell resistance to posttransplantation cyclophosphamide. Sci Transl Med. 2013 Nov 13; 5(211):211ra157.
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Mechanisms of tolerance to parental parathyroid tissue when combined with human allogeneic thymus transplantation. J Allergy Clin Immunol. 2010 Oct; 126(4):814-820.e8.
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Cross talk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells. Blood. 2010 Jul 15; 116(2):210-7.
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Chemokine receptor CCR5 mediates alloimmune responses in graft-versus-host disease. Biol Blood Marrow Transplant. 2010 Mar; 16(3):311-9.
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Human liver dendritic cells promote T cell hyporesponsiveness. J Immunol. 2009 Feb 15; 182(4):1901-11.
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Spontaneous recovery from early glomerular inflammation is associated with resistance to anti-GBM glomerulonephritis: tolerance and autoimmune tissue injury. J Autoimmun. 2008 Jun; 30(4):246-56.
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A novel role for the semaphorin Sema4D in the induction of allo-responses. Biol Blood Marrow Transplant. 2007 Nov; 13(11):1294-1303.
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Thymosin-alpha1 modulates dendritic cell differentiation and functional maturation from human peripheral blood CD14+ monocytes. Immunol Lett. 2007 Jun 15; 110(2):110-20.