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SUBBIAH, VIVEK
One or more keywords matched the following items that are connected to SUBBIAH, VIVEK
Item TypeName
Academic Article Bilateral gonadoblastoma with dysgerminoma and pilocytic astrocytoma with WT1 GT-IVS9 mutation: A 46 XY phenotypic female with Frasier syndrome.
Academic Article 99mTc-sestamibi scan differentiates tumor from other contrast enhancing tissue in choroid plexus tumors.
Academic Article Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery.
Concept Colorectal Neoplasms, Hereditary Nonpolyposis
Concept Gastrointestinal Stromal Tumors
Concept Biliary Tract Neoplasms
Concept Choroid Plexus Neoplasms
Concept Thyroid Neoplasms
Concept Neuroendocrine Tumors
Concept Adrenal Cortex Neoplasms
Concept Neoplasms, Multiple Primary
Concept Tumor Burden
Concept Esophageal Neoplasms
Concept Brain Neoplasms
Concept Lung Neoplasms
Concept Uterine Neoplasms
Concept Wilms Tumor
Concept Neoplasms, Germ Cell and Embryonal
Concept Tumor Suppressor Protein p53
Concept Prostatic Neoplasms
Concept Neoplasm Metastasis
Concept Granulosa Cell Tumor
Concept Biomarkers, Tumor
Concept Antigens, Neoplasm
Concept Gallbladder Neoplasms
Concept Ovarian Neoplasms
Concept Antigens, Tumor-Associated, Carbohydrate
Concept Urogenital Neoplasms
Concept Meningeal Neoplasms
Concept DNA, Neoplasm
Concept Mediastinal Neoplasms
Concept Neuroectodermal Tumors
Concept Urinary Bladder Neoplasms
Concept Retroperitoneal Neoplasms
Concept Rhabdoid Tumor
Concept Colorectal Neoplasms
Concept Pancreatic Neoplasms
Concept Hypothalamic Neoplasms
Concept Genes, Wilms Tumor
Concept Neoplasm Proteins
Concept Neoplasm Staging
Concept Kidney Neoplasms
Concept Drug Resistance, Neoplasm
Concept Neoplasm Transplantation
Concept Hypopharyngeal Neoplasms
Concept Breast Neoplasms
Concept Stomach Neoplasms
Concept Bone Neoplasms
Concept Perivascular Epithelioid Cell Neoplasms
Concept Phyllodes Tumor
Concept Head and Neck Neoplasms
Concept Lymphocytes, Tumor-Infiltrating
Concept Femoral Neoplasms
Concept Bile Duct Neoplasms
Concept Heart Neoplasms
Concept Neoplasms, Glandular and Epithelial
Concept Abdominal Neoplasms
Concept Pelvic Neoplasms
Concept Neoplasms
Concept Skin Neoplasms
Concept Neoplasm, Residual
Concept Colonic Neoplasms
Concept Cell Line, Tumor
Concept Gastrointestinal Neoplasms
Concept Neoplasm Recurrence, Local
Concept Giant Cell Tumor of Bone
Concept Intestinal Neoplasms
Concept Peritoneal Neoplasms
Concept Genes, Neoplasm
Concept Liver Neoplasms
Concept Soft Tissue Neoplasms
Concept Neoplasm Invasiveness
Concept Testicular Neoplasms
Concept Endometrial Neoplasms
Academic Article Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications.
Academic Article Ewing's sarcoma: standard and experimental treatment options.
Academic Article Neoadjuvant treatment of soft-tissue sarcoma: a multimodality approach.
Academic Article Case 36-2009: A man with cough, hoarseness, and abnormalities on chest imaging.
Academic Article There are still some things money can't buy.
Academic Article Review: Ewing sarcoma treatment: a role for bisphosphonates?
Academic Article To ring or wring the bell?
Academic Article Targeted therapy by combined inhibition of the RAF and mTOR kinases in malignant spindle cell neoplasm harboring the KIAA1549-BRAF fusion protein.
Academic Article Modifiers of risk for infectious complications of cancer therapy in children: the long road ahead.
Academic Article Outcomes of splenectomy in T-cell large granular lymphocyte leukemia with splenomegaly and cytopenia.
Academic Article [90Y]yttrium microspheres radioembolotherapy in desmoplastic small round cell tumor hepatic metastases.
Academic Article How watching the movie Zombieland helps treatment of cancer in teenagers.
Academic Article Gastric adenocarcinoma in children and adolescents.
Academic Article A friend request: to accept or decline?
Academic Article Resistance to mammalian target of rapamycin inhibitor therapy in perivascular epithelioid cell tumors.
Academic Article Happy or unhappy christmas?
Academic Article Targeted morphoproteomic profiling of Ewing's sarcoma treated with insulin-like growth factor 1 receptor (IGF1R) inhibitors: response/resistance signatures.
Academic Article Phase 1 clinical trials for sarcomas: the cutting edge.
Academic Article Advanced atypical teratoid/rhabdoid tumor (ATRT) treated with intensive multimodal approach shows continued response to sarcoma type salvage therapy.
Academic Article Targeting the apoptotic pathway in chondrosarcoma using recombinant human Apo2L/TRAIL (dulanermin), a dual proapoptotic receptor (DR4/DR5) agonist.
Academic Article Targeted therapy of advanced gallbladder cancer and cholangiocarcinoma with aggressive biology: eliciting early response signals from phase 1 trials.
Academic Article Comprehensive characterization of malignant phyllodes tumor by whole genomic and proteomic analysis: biological implications for targeted therapy opportunities.
Academic Article Morphoproteomic profiling of the mammalian target of rapamycin (mTOR) signaling pathway in desmoplastic small round cell tumor (EWS/WT1), Ewing's sarcoma (EWS/FLI1) and Wilms' tumor(WT1).
Academic Article FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors.
Academic Article Bone-seeking radiopharmaceuticals as targeted agents of osteosarcoma: samarium-153-EDTMP and radium-223.
Academic Article Adolescent oncology: who cares?-the new KID on the block.
Academic Article Rapid response to therapy of neurocutaneous melanosis with leptomeningeal melanoma.
Academic Article Killing two birds with one stone: BRAF V600E inhibitor therapy for hairy cell leukemia and Langerhans/dendritic cell sarcoma.
Academic Article MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit.
Academic Article Unique molecular signatures as a hallmark of patients with metastatic breast cancer: implications for current treatment paradigms.
Academic Article Prospects and pitfalls of personalizing therapies for sarcomas: from children, adolescents, and young adults to the elderly.
Academic Article Analysis of MET genetic aberrations in patients with breast cancer at MD Anderson Phase I unit.
Academic Article Next generation sequencing analysis of platinum refractory advanced germ cell tumor sensitive to Sunitinib (Sutent?) a VEGFR2/PDGFR?/c-kit/ FLT3/RET/CSF1R inhibitor in a phase II trial.
Academic Article MET abnormalities in patients with genitourinary malignancies and outcomes with c-MET inhibitors.
Academic Article Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumors.
Academic Article Synergy between VEGF/VEGFR inhibitors and chemotherapy agents in the phase I clinic.
Academic Article Targeted therapy for hereditary cancer syndromes: hereditary breast and ovarian cancer syndrome, Lynch syndrome, familial adenomatous polyposis, and Li-Fraumeni syndrome.
Academic Article Exceptional responders: in search of the science behind the miracle cancer cures.
Academic Article Phase I study of pazopanib and vorinostat: a therapeutic approach for inhibiting mutant p53-mediated angiogenesis and facilitating mutant p53 degradation.
Academic Article Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors.
Academic Article Targeted therapy for genetic cancer syndromes: Fanconi anemia, medullary thyroid cancer, tuberous sclerosis, and RASopathies.
Academic Article Targeted therapy for genetic cancer syndromes: Von Hippel-Lindau disease, Cowden syndrome, and Proteus syndrome.
Academic Article Photoallergic reaction in a patient receiving vandetanib for metastatic follicular thyroid carcinoma: a case report.
Academic Article Phase I combination of pazopanib and everolimus in PIK3CA mutation positive/PTEN loss patients with advanced solid tumors refractory to standard therapy.
Academic Article Systemic and CNS activity of the RET inhibitor vandetanib combined with the mTOR inhibitor everolimus in KIF5B-RET re-arranged non-small cell lung cancer with brain metastases.
Academic Article Clinical next generation sequencing to identify actionable aberrations in a phase I program.
Academic Article STUMP un"stumped": anti-tumor response to anaplastic lymphoma kinase (ALK) inhibitor based targeted therapy in uterine inflammatory myofibroblastic tumor with myxoid features harboring DCTN1-ALK fusion.
Academic Article Exploring response signals and targets in aggressive unresectable hepatocellular carcinoma: an analysis of targeted therapy phase 1 trials.
Academic Article Alpha Emitter Radium 223 in High-Risk Osteosarcoma: First Clinical Evidence of Response and Blood-Brain Barrier Penetration.
Academic Article Vemurafenib in Multiple Nonmelanoma Cancers with BRAF V600 Mutations.
Academic Article BRAF mutation testing with a rapid, fully integrated molecular diagnostics system.
Academic Article Evaluation of 122 advanced-stage cutaneous squamous cell carcinomas by comprehensive genomic profiling opens the door for new routes to targeted therapies.
Academic Article Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine.
Academic Article Cognitive Changes During Chemotherapy.
Academic Article Radium-223 dichloride therapy in breast cancer with osseous metastases.
Academic Article Phase I dose escalation study of temsirolimus in combination with metformin in patients with advanced/refractory cancers.
Academic Article BRAF Mutation Testing in Cell-Free DNA from the Plasma of Patients with Advanced Cancers Using a Rapid, Automated Molecular Diagnostics System.
Academic Article Activity of c-Met/ALK Inhibitor Crizotinib and Multi-Kinase VEGF Inhibitor Pazopanib in Metastatic Gastrointestinal Neuroectodermal Tumor Harboring EWSR1-CREB1 Fusion
Academic Article Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors
Academic Article Genomically driven tumors and actionability across histologies
Academic Article Continuous anti-angiogenic therapy after tumor progression in patients with recurrent high-grade epithelial ovarian cancer
Academic Article Incidence of immune-related adverse events and its association with treatment outcomes: the MD Anderson Cancer Center experience.
Academic Article Headache in a patient with renal cell carcinoma.
Academic Article Antitumor Response to Combined Antiangiogenic and Cytotoxic Chemotherapy in Recurrent Metastatic Chromophobe Renal Cell Carcinoma: Response Signatures and Proteomic Correlates.
Academic Article Universal Genomic Testing Needed to Win the War Against Cancer: Genomics IS the Diagnosis.
Academic Article Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab, anti-EGFR antibody cetuximab, and the mTOR inhibitor temsirolimus.
Academic Article Genomically Driven Tumors and Actionability across Histologies: BRAF-Mutant Cancers as a Paradigm.
Academic Article Comprehensive genomic profiling of 295 cases of clinically advanced urothelial carcinoma of the urinary bladder reveals a high frequency of clinically relevant genomic alterations.
Academic Article Clinical activity of ceritinib in ROS1-rearranged non-small cell lung cancer: Bench to bedside report.
Academic Article TP53 Alterations Correlate with Response to VEGF/VEGFR Inhibitors: Implications for Targeted Therapeutics.
Academic Article Continuous anti-angiogenic therapy after tumor progression in patients with recurrent high-grade epithelial ovarian cancer: phase I trial experience.
Academic Article Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma.
Academic Article IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma.
Academic Article Ipilimumab with Stereotactic Ablative Radiation Therapy: Phase I Results and Immunologic Correlates from Peripheral T Cells.
Academic Article Cancer Therapy Directed by Comprehensive Genomic Profiling: A Single Center Study.
Academic Article Sleep quality and its association with fatigue, symptom burden, and mood in patients with advanced cancer in a clinic for early-phase oncology clinical trials.
Academic Article Jaundice (Hyperbilirubinemia) in Cancer.
Academic Article Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials.
Academic Article Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy.
Academic Article Evaluation of Novel Targeted Therapies in Aggressive Biology Sarcoma Patients after progression from US FDA approved Therapies.
Academic Article Survival of patients with metastatic leiomyosarcoma: the MD Anderson Clinical Center for targeted therapy experience.
Academic Article Targeting the PI3K/AKT/mTOR Pathway for the Treatment of Mesenchymal Triple-Negative Breast Cancer: Evidence From a Phase 1 Trial of mTOR Inhibition in Combination With Liposomal Doxorubicin and Bevacizumab.
Academic Article Phase IB Study of Vemurafenib in Combination with Irinotecan and Cetuximab in Patients with Metastatic Colorectal Cancer with BRAFV600E Mutation.
Academic Article Post-Discharge Survival Outcomes of Patients with Advanced Cancer from the University of Texas MD Anderson Cancer Center Investigational Cancer Therapeutics (Phase I Trials) Inpatient Unit.
Academic Article RET Aberrations in Diverse Cancers: Next-Generation Sequencing of 4,871 Patients.
Academic Article Activity of c-Met/ALK Inhibitor Crizotinib and Multi-Kinase VEGF Inhibitor Pazopanib in Metastatic Gastrointestinal Neuroectodermal Tumor Harboring EWSR1-CREB1 Fusion.
Academic Article Mutation-Enrichment Next-Generation Sequencing for Quantitative Detection of KRAS Mutations in Urine Cell-Free DNA from Patients with Advanced Cancers.
Academic Article Phase I clinical trial of combination imatinib and ipilimumab in patients with advanced malignancies.
Academic Article Antiangiogenesis and gene aberration-related therapy may improve overall survival in patients with concurrent KRAS and TP53 hotspot mutant cancer.
Academic Article The oral VEGF receptor tyrosine kinase inhibitor pazopanib in combination with the MEK inhibitor trametinib in advanced cholangiocarcinoma.
Academic Article Towards precision oncology in RET-aberrant cancers.
Academic Article Clinical genomic profiling to identify actionable alterations for investigational therapies in patients with diverse sarcomas.
Academic Article Development and Validation of an Ultradeep Next-Generation Sequencing Assay for Testing of Plasma Cell-Free DNA from Patients with Advanced Cancer.
Academic Article Dabrafenib and Trametinib Treatment in Patients With Locally Advanced or Metastatic BRAF V600-Mutant Anaplastic Thyroid Cancer.
Academic Article Liquid Biopsies Using Plasma Exosomal Nucleic Acids and Plasma Cell-Free DNA Compared with Clinical Outcomes of Patients with Advanced Cancers.
Academic Article Co-occurring Genomic Alterations and Association With Progression-Free Survival in BRAFV600-Mutated Nonmelanoma Tumors.
Academic Article Myeloid/lymphoid neoplasms with FGFR1 rearrangement.
Academic Article Quantification of the Effect of Shuttling on Computed Tomography Perfusion Parameters by Investigation of Aortic Inputs on Different Table Positions From Shuttle-Mode Scans of Lung and Liver Tumors.
Academic Article Phase I Dose-Escalation Study of Anti-CTLA-4 Antibody Ipilimumab and Lenalidomide in Patients with Advanced Cancers.
Academic Article Precision oncology: East meets West.
Academic Article Phase I study of the combination of crizotinib (as a MET inhibitor) and dasatinib (as a c-SRC inhibitor) in patients with advanced cancer.
Academic Article The big, the bad, and the exon 11: adjuvant imatinib for all gastro-intestinal stromal tumors or just the ugly?
Academic Article Counterpoint: Successes in the Pursuit of Precision Medicine: Biomarkers Take Credit.
Academic Article Phase Ib/II Trial of NC-6004 (Nanoparticle Cisplatin) Plus Gemcitabine in Patients with Advanced Solid Tumors.
Academic Article Phase I study of nab-paclitaxel, gemcitabine, and bevacizumab in patients with advanced cancers.
Academic Article Challenging Standard-of-Care Paradigms in the Precision Oncology Era.
Academic Article Development of a prognostic scoring system for patients with advanced cancer enrolled in immune checkpoint inhibitor phase 1 clinical trials.
Academic Article Evaluating for Pseudoprogression in Colorectal and Pancreatic Tumors Treated With Immunotherapy.
Academic Article Predicting outcomes in patients with advanced non-small cell lung cancer enrolled in early phase immunotherapy trials.
Academic Article Mesenchymal Chondrosarcoma: a Review with Emphasis on its Fusion-Driven Biology.
Academic Article Clinical Next-Generation Sequencing for Precision Oncology in Rare Cancers.
Academic Article Precision Targeted Therapy with BLU-667 for RET-Driven Cancers.
Academic Article Clinical Activity of Pazopanib in Patients with Advanced Desmoplastic Small Round Cell Tumor.
Academic Article A phase I clinical trial of hepatic arterial infusion of oxaliplatin and oral capecitabine, with or without intravenous bevacizumab, in patients with advanced cancer and predominant liver involvement.
Academic Article Multimodality Treatment of Desmoplastic Small Round Cell Tumor: Chemotherapy and Complete Cytoreductive Surgery Improve Patient Survival.
Academic Article Cytokines Produced by Dendritic Cells Administered Intratumorally Correlate with Clinical Outcome in Patients with Diverse Cancers.
Academic Article Calcinosis cutis dermatologic toxicity associated with fibroblast growth factor receptor inhibitor for the treatment of Wilms tumor.
Academic Article Alpha Particle Radium 223 Dichloride in High-risk Osteosarcoma: A Phase I Dose Escalation Trial.
Academic Article High-Throughput Architecture for Discovering Combination Cancer Therapeutics.
Academic Article Cancer-Related Internet Use and Online Social Networking Among Patients in an Early-Phase Clinical Trials Clinic at a Comprehensive Cancer Center.
Academic Article Phase 1 study of the combination of vemurafenib, carboplatin, and paclitaxel in patients with BRAF-mutated melanoma and other advanced malignancies.
Academic Article Cancer-Related Internet Use and Its Association With Patient Decision Making and Trust in Physicians Among Patients in an Early Drug Development Clinic: A Questionnaire-Based Cross-Sectional Observational Study.
Academic Article BRAF Inhibition in BRAFV600-Mutant Gliomas: Results From the VE-BASKET Study.
Academic Article Comprehensive molecular imaging of malignant transformation of giant cell tumour of bone reveals diverse disease biology.
Academic Article Molecular imaging of metastatic atrial angiosarcoma with positron emission tomography (PET) tracer 3'-deoxy-3'[(18)F]-fluorothymidine, [(18)F]-FLT imaging and early response evaluation.
Concept Circulating Tumor DNA
Concept Desmoplastic Small Round Cell Tumor
Concept Tumor Microenvironment
Concept Neoplasm Grading
Concept Triple Negative Breast Neoplasms
Concept Response Evaluation Criteria in Solid Tumors
Academic Article A Phase I Trial of the VEGF Receptor Tyrosine Kinase Inhibitor Pazopanib in Combination with the MEK Inhibitor Trametinib in Advanced Solid Tumors and Differentiated Thyroid Cancers.
Academic Article Analysis of Cell-Free DNA from 32,989 Advanced Cancers Reveals Novel Co-occurring Activating RET Alterations and Oncogenic Signaling Pathway Aberrations.
Academic Article Phase II clinical trial of pembrolizumab efficacy and safety in advanced adrenocortical carcinoma.
Academic Article Novel use of a Clinical Laboratory Improvements Amendments (CLIA)-certified Cyclin-Dependent Kinase N2C (CDKN2C) loss assay in?sporadic medullary thyroid carcinoma.
Academic Article Response to Mammalian Target of Rapamycin-Based Therapy and Incidental Finding of Lynch Syndrome in a Patient With Solid Pseudopapillary Neoplasm of the Pancreas With AKT1_E17K Mutation.
Academic Article Phase II Trial of Ipilimumab with Stereotactic Radiation Therapy for Metastatic Disease: Outcomes, Toxicities, and Low-Dose Radiation-Related Abscopal Responses.
Academic Article Imaging of acute abdomen in cancer patients.
Academic Article Precision Oncology for Hepatocellular Cancer: Slivering the Liver by FGF19-FGF4-KLB Pathway Inhibition.
Academic Article Cell-free Circulating Tumor DNA Variant Allele Frequency Associates with Survival in Metastatic Cancer.
Academic Article RET Solvent Front Mutations Mediate Acquired?Resistance to Selective RET Inhibition in?RET-Driven Malignancies.
Academic Article Pan-Cancer Efficacy of Vemurafenib in BRAFV600-Mutant Non-Melanoma Cancers.
Academic Article Phase I studies of vorinostat with ixazomib or pazopanib imply a role of antiangiogenesis-based therapy for TP53 mutant malignancies.
Academic Article State-of-the-Art Strategies for Targeting RET-Dependent Cancers.
Academic Article Advances in Targeting RET-Dependent Cancers.
Academic Article Hyperprogression and Immunotherapy: Fact, Fiction, or Alternative Fact?
Academic Article Genomics, Morphoproteomics, and Treatment Patterns of Patients with Alveolar Soft Part Sarcoma and Response to Multiple Experimental Therapies.
Academic Article Phase 2 study of pembrolizumab in patients with advanced rare cancers.
Academic Article Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial.
Academic Article 223-Radium for metastatic osteosarcoma: combination therapy with other agents and external beam radiotherapy.
Academic Article Dual EGFR blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation triplet combination trial.
Academic Article Managing Cancer Care during the COVID-19 Pandemic and Beyond.
Academic Article Clinical Development of BRAF plus MEK Inhibitor Combinations.
Academic Article Progresses Toward Precision Medicine in RET-altered Solid Tumors.
Academic Article Progression-free survival is a suboptimal predictor for overall survival among metastatic solid tumour clinical trials.
Academic Article The FDA approval of pembrolizumab for adult and pediatric patients with tumor mutational burden (TMB) =10: a decision centered on empowering patients and their physicians.
Academic Article Phase I Study of P-cadherin-targeted Radioimmunotherapy with 90Y-FF-21101 Monoclonal Antibody in Solid Tumors.
Academic Article Dabrafenib plus trametinib in patients with BRAFV600E-mutated biliary tract cancer (ROAR): a phase 2, open-label, single-arm, multicentre basket trial.
Academic Article Dual inhibition of BRAF and mTOR in BRAFV600E -mutant pediatric, adolescent, and young adult brain tumors.
Academic Article Efficacy of Selpercatinib in RET Fusion-Positive Non-Small-Cell Lung Cancer.
Academic Article Efficacy of Selpercatinib in RET-Altered Thyroid Cancers.
Academic Article Targeting ERBB2 (HER2) Amplification Identified by Next-Generation Sequencing in Patients With Advanced or Metastatic Solid Tumors Beyond Conventional Indications.
Academic Article From Tissue-Agnostic to N-of-One Therapies: (R)Evolution of the Precision Paradigm.
Academic Article Sequencing PEComas: Viewing Unicorns through the Molecular Looking Glass.
Academic Article Antitumor activity of lurbinectedin in second-line small cell lung cancer patients who are candidates for re-challenge with the first-line treatment.
Academic Article Responsiveness to immune checkpoint inhibitors versus other systemic therapies in RET-aberrant malignancies.
Academic Article Effect of lurbinectedin on the QTc interval in patients with advanced solid tumors: an exposure-response analysis.
Academic Article Phase I Study of Everolimus, Letrozole, and Trastuzumab in Patients with Hormone Receptor-positive Metastatic Breast Cancer or Other Solid Tumors.
Academic Article Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations.
Academic Article Neoadjuvant selpercatinib for advanced medullary thyroid cancer.
Academic Article Dabrafenib plus trametinib in patients with BRAFV600E-mutated biliary tract cancer - Authors' reply.
Academic Article Validation of prognostic scoring systems for patients with metastatic renal cell carcinoma enrolled in phase I clinical trials.
Academic Article Molecular Profiling of Metastatic Bladder Cancer Early-Phase Clinical Trial Participants Predicts Patient Outcomes.
Academic Article The clinical efficacy and safety of single-agent pembrolizumab in patients with recurrent granulosa cell tumors of the ovary: a case series from a phase II basket trial.
Academic Article Pembrolizumab in Patients with Advanced Metastatic Germ Cell Tumors.
Academic Article Phase I study of ABBV-428, a mesothelin-CD40 bispecific, in patients with advanced solid tumors.
Academic Article Patient-driven discovery and post-clinical validation of NTRK3 fusion as an acquired resistance mechanism to selpercatinib in RET fusion-positive lung cancer.
Academic Article Phase 1 trial of ADI-PEG20 plus cisplatin in patients with pretreated metastatic melanoma or other advanced solid malignancies.
Academic Article COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials.
Academic Article A Phase I Dose-Escalation Study to Evaluate the Safety and Tolerability of Evofosfamide in Combination with Ipilimumab in Advanced Solid Malignancies.
Academic Article First-in-Human Phase I Study of ABBV-085, an Antibody-Drug Conjugate Targeting LRRC15, in Sarcomas and Other Advanced Solid Tumors.
Academic Article Patient-Reported Out-of-Pocket Costs and Financial Toxicity During Early-Phase Oncology Clinical Trials.
Academic Article Immunotherapy in non-small cell lung cancer harbouring driver mutations.
Academic Article Radiomics analysis for predicting pembrolizumab response in patients with advanced rare cancers.
Academic Article Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study.
Academic Article Intracranial Efficacy of Selpercatinib in RET Fusion-Positive Non-Small Cell Lung Cancers on the LIBRETTO-001 Trial.
Academic Article Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study.
Academic Article Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi-cohort, open-label, registrational, phase 1/2 study.
Academic Article Validation of Prognostic Scores in Patients With Metastatic Urothelial Cancer Enrolling in Phase I Targeted Therapy or Next Generation Immunotherapy Trials.
Academic Article Precision therapy for RET-altered cancers with RET inhibitors.
Academic Article Retrospective Case Series Analysis of RAF Family Alterations in Pancreatic Cancer: Real-World Outcomes From Targeted and Standard Therapies.
Academic Article A phase i study of ixazomib and erlotinib in patients with advanced solid tumors.
Academic Article Hallmarks of RET and Co-occuring Genomic Alterations in RET-aberrant Cancers.
Academic Article A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation.
Academic Article Patient-Reported Outcomes with Selpercatinib Treatment Among Patients with RET-Mutant Medullary Thyroid Cancer in the Phase I/II LIBRETTO-001 Trial.
Academic Article A Phase 1 Study of a CDH6-Targeting Antibody-Drug Conjugate in Patients with Advanced Solid Tumors with Evaluation of Inflammatory and Neurological Adverse Events.
Academic Article The value of innovation: association between improvements in survival of advanced and metastatic non-small cell lung cancer and targeted and immunotherapy.
Academic Article Patient-Reported Outcomes with Selpercatinib Among Patients with RET Fusion-Positive Non-Small Cell Lung Cancer in the Phase I/II LIBRETTO-001 Trial.
Academic Article EGFR and HER2 exon 20 insertions in solid tumours: from biology to treatment.
Academic Article Correction to: Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study.
Academic Article 18F-sodium fluoride positron emission tomography (NaF-18-PET/CT) radiomic signatures to evaluate responses to alpha-particle Radium-223 dichloride therapy in osteosarcoma metastases.
Academic Article Optimizing anti-body drug conjugates and radiopharmaceuticals for precision therapy: The next frontier in precision oncology.
Academic Article Comparative Effectiveness of Atezolizumab, Nivolumab, and Docetaxel in Patients With Previously Treated Non-Small Cell Lung Cancer.
Academic Article Dabrafenib plus trametinib in patients with BRAFV600E-mutant low-grade and high-grade glioma (ROAR): a multicentre, open-label, single-arm, phase 2, basket trial.
Academic Article Impact of tissue-agnostic approvals for patients with sarcoma.
Academic Article Selinexor in combination with standard chemotherapy in patients with advanced or metastatic solid tumors.
Academic Article Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction.
Academic Article A First-in-Human, Phase I, Multicenter, Open-Label, Dose-Escalation Study of PCA062: An Antibody-Drug Conjugate Targeting P-Cadherin, in Patients With Solid Tumors.
Academic Article A global effort to understand the riddles of COVID-19 and cancer.
Academic Article Tissue/Site-Agnostic Study of Ribociclib for Tumors With Cyclin D-CDK4/6 Pathway Genomic Alterations: A Phase II, Open-Label, Single-Arm Basket Study.
Academic Article FIGHT-101, a first-in-human study of potent and selective FGFR 1-3 inhibitor pemigatinib in pan-cancer patients with FGF/FGFR alterations and advanced malignancies.
Academic Article Tissue-Agnostic Activity of BRAF plus MEK Inhibitor in BRAF V600-Mutant Tumors.
Academic Article Antitumor Activity of Lurbinectedin, a Selective Inhibitor of Oncogene Transcription, in Patients with Relapsed Ewing Sarcoma: Results of a Basket Phase II Study.
Academic Article Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences.
Academic Article Association Between Smoking History and Overall Survival in Patients Receiving Pembrolizumab for First-Line Treatment of Advanced Non-Small Cell Lung Cancer.
Academic Article Addressing challenges with real-world synthetic control arms to demonstrate the comparative effectiveness of Pralsetinib in non-small cell lung cancer.
Academic Article Longitudinal Monitoring of Circulating Tumor DNA to Predict Treatment Outcomes in Advanced Cancers.
Academic Article Lurbinectedin in patients with pretreated neuroendocrine tumours: Results from a phase II basket study.
Academic Article Strategies for Mitigating Antibody-Drug Conjugate Related Adverse Events for Precision Therapy.
Academic Article Drugging KRAS: current perspectives and state-of-art review.
Academic Article Examining Stripes on a Herd of Zebras: Impact of Genomic Matching for Ultrarare Sarcomas in Phase 1 Clinical Trials (SAMBA 102).
Academic Article Osteosarcoma with cell-cycle and fibroblast growth factor genomic alterations: case report of Molecular Tumor Board combination strategy resulting in long-term exceptional response.
Academic Article Clinical Activity of Mitogen-Activated Protein Kinase-Targeted Therapies in Patients With Non-V600 BRAF-Mutant Tumors.
Academic Article Tilsotolimod Exploits the TLR9 Pathway to Promote Antigen Presentation and Type 1 IFN Signaling in Solid Tumors: A Multicenter International Phase I/II Trial (ILLUMINATE-101).
Academic Article Accelerated approvals hit the target in precision oncology.
Academic Article Exportin(g) precision oncology beyond genomics with XPO1 inhibition.
Academic Article Selpercatinib in Patients With RET Fusion-Positive Non-Small-Cell Lung Cancer: Updated Safety and Efficacy From the Registrational LIBRETTO-001 Phase I/II Trial.
Academic Article Neoadjuvant Selective RET Inhibitor for Medullary Thyroid Cancer: A Case Series.
Academic Article Pan-cancer efficacy of pralsetinib in patients with RET fusion-positive solid tumors from the phase 1/2 ARROW trial.
Academic Article Tumour-agnostic efficacy and safety of selpercatinib in patients with RET fusion-positive solid tumours other than lung or thyroid tumours (LIBRETTO-001): a phase 1/2, open-label, basket trial.
Academic Article The Armed Conflict and the Impact on Patients With Cancer in Ukraine: Urgent Considerations.
Academic Article RET aberrant cancers and RET inhibitor therapies: Current state-of-the-art and future perspectives.
Academic Article Rationalizing rules for immunotherapy combination trials: About time for precision immunotherapy.
Academic Article Transportability of Overall Survival Estimates From US to Canadian Patients With Advanced Non-Small Cell Lung Cancer With Implications for Regulatory and Health Technology Assessment.
Academic Article Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials.
Academic Article Patient-reported symptom burden in patients with rare cancers receiving pembrolizumab in a phase II Clinical Trial.
Academic Article Impact of tissue-agnostic approvals for patients with gastrointestinal malignancies.
Academic Article International multicenter study comparing COVID-19 in patients with cancer to patients without cancer: Impact of risk factors and treatment modalities on survivorship.
Academic Article Surgery After BRAF-Directed Therapy Is Associated with Improved Survival in BRAFV600E Mutant Anaplastic Thyroid Cancer: A Single-Center Retrospective Cohort Study.
Academic Article The abscopal effect in patients with cancer receiving immunotherapy.
Academic Article A phase 1/2a safety, pharmacokinetics, and efficacy study of the novel nucleoside analog FF-10502-01 for the treatment of advanced solid tumors.
Academic Article The emerging role of PI3K inhibitors for solid tumour treatment and beyond.
Academic Article Universal Germline and Tumor Genomic Testing Needed to Win the War Against Cancer: Genomics Is the Diagnosis.
Academic Article Top advances of the year: Precision oncology.
Academic Article Utility of Established Prognostic Scoring Systems for Patients with Advanced Pancreatic Adenocarcinoma Enrolled in Immunotherapy-Based Early-Phase Clinical Trials.
Academic Article Impact of Biomarker-Matched Therapies on Outcomes in Patients with Sarcoma Enrolled in Early-Phase Clinical Trials (SAMBA 101).
Academic Article Tumor-Agnostic Precision Medicine from the AACR GENIE Database: Clinical Implications.
Academic Article N-of-1 Trials in Cancer Drug Development.
Academic Article Expanding the Benefit: Dabrafenib/Trametinib as Tissue-Agnostic Therapy for BRAF V600E-Positive Adult and Pediatric Solid Tumors.
Academic Article A Phase I Trial of Bevacizumab and Temsirolimus in Combination With Valproic Acid in Advanced Solid Tumors.
Academic Article A phase I trial of the pan-ERBB inhibitor neratinib combined with the MEK inhibitor trametinib in patients with advanced cancer with EGFR mutation/amplification, HER2 mutation/amplification, HER3/4 mutation or KRAS mutation.
Academic Article Lurbinectedin, a DNA minor groove inhibitor for neuroendocrine neoplasms beyond small cell lung cancer.
Academic Article Predicting the Abscopal Effect: Associated Tumor Histologic Subtypes and Biomarkers.
Academic Article Translating immuno-onco-microbiome-based therapeutics: precision bugs for immune checkpoint drugs!
Academic Article Preclinical Characterization and Phase I Trial Results of INBRX-109, A Third-Generation, Recombinant, Humanized, Death Receptor 5 Agonist Antibody, in Chondrosarcoma.
Academic Article RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations.
Academic Article Immune-checkpoint inhibition for resectable non-small-cell lung cancer - opportunities and challenges.
Academic Article The Landscape of Alterations from 1407 Ultra-Rare Sarcomas from the AACR GENIE Database: Clinical Implications.
Academic Article Multi-disciplinary management of recurrent gastrointestinal stromal tumor harboring KIT exon 11 mutation with the switch-control kinase inhibitor ripretinib and surgery.
Academic Article Tumor-agnostic drug development in dMMR/MSI-H solid tumors.
Academic Article Pooled Safety Analysis of Single-Agent Lurbinectedin in Patients With Advanced Solid Tumours.
Academic Article Selpercatinib and Pralsetinib Induced Chylous Ascites in RET-Rearranged Lung Adenocarcinoma: A Case Series.
Academic Article Lurbinectedin in patients with pretreated endometrial cancer: results from a phase 2 basket clinical trial and exploratory translational study.
Academic Article Clinico-Genomic Profiling of Conventional and Dedifferentiated Chondrosarcomas Reveals TP53 Mutation to Be Associated with Worse Outcomes.
Academic Article TRKing sarcomas for precision medicine: Seek, and ye shall find!
Academic Article RETooling the RET Inhibitor Pralsetinib for ESR1 Fusion-Positive Breast Cancer and Beyond.
Academic Article Association between treatment and improvements in overall survival of patients with advanced/metastatic non-small cell lung cancer since 2011: A study in the United States, Canada, and Germany using retrospective real-world databases.
Academic Article Revolutionizing cancer drug development: Harnessing the potential of basket trials.
Academic Article Pralsetinib in Patients with Advanced/Metastatic Rearranged During Transfection (RET)-Altered Thyroid Cancer: Updated Efficacy and Safety Data from the ARROW Study.
Academic Article Circulating Tumor DNA Enables Sensitive Detection of Actionable Gene Fusions and Rearrangements Across Cancer Types.
Academic Article Exceptional Responses to Selpercatinib in RET Fusion-Driven Metastatic Pancreatic Cancer.
Academic Article Lurbinectedin in patients with small cell lung cancer with chemotherapy-free interval =30 days and without central nervous metastases.
Academic Article Impact of tissue-agnostic approvals on management of primary brain tumors.
Academic Article Phase I study of sapanisertib (CB-228/TAK-228/MLN0128) in combination with ziv-aflibercept in patients with advanced solid tumors.
Academic Article A Vision for Democratizing Next-Generation Oncology Clinical Trials.
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