"Granulosa Cell Tumor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
| Descriptor ID |
D006106
|
| MeSH Number(s) |
C04.557.475.750.656 C04.588.322.455.398 C13.351.500.056.630.705.398 C13.351.937.418.685.398 C19.344.410.398 C19.391.630.705.398
|
| Concept/Terms |
Granulosa Cell Tumor- Granulosa Cell Tumor
- Granulosa Cell Tumors
- Tumor, Granulosa Cell
- Tumors, Granulosa Cell
Granulosa Cell Cancer- Granulosa Cell Cancer
- Cancer, Granulosa Cell
- Cancers, Granulosa Cell
- Cell Cancer, Granulosa
- Cell Cancers, Granulosa
- Granulosa Cell Cancers
- Cancer of Granulosa Cells
- Cells Cancer, Granulosa
- Cells Cancers, Granulosa
- Granulosa Cells Cancer
- Granulosa Cells Cancers
|
Below are MeSH descriptors whose meaning is more general than "Granulosa Cell Tumor".
Below are MeSH descriptors whose meaning is more specific than "Granulosa Cell Tumor".
This graph shows the total number of publications written about "Granulosa Cell Tumor" by people in this website by year, and whether "Granulosa Cell Tumor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 2 | 1 | 3 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Granulosa Cell Tumor" by people in Profiles.
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Differences in gynecologic tumor development in Amhr2-Cre mice with KRASG12D or KRASG12V mutations. Sci Rep. 2020 11 26; 10(1):20678.
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Sex Cord Tumor With Annular Tubules-Like Histologic Pattern in Adult Granulosa Cell Tumor: Case Report of a Hitherto Unreported Morphologic Variant. Int J Surg Pathol. 2021 Jun; 29(4):433-437.
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RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line. Int J Mol Sci. 2019 Jul 15; 20(14).
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Multimodal molecular analysis of an atypical small cell carcinoma of the ovary, hypercalcemic type. Cold Spring Harb Mol Case Stud. 2018 10; 4(5).
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From Follicular Development and Ovulation to Ovarian Cancers: An Unexpected Journey. Vitam Horm. 2018; 107:453-472.
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Juvenile Granulosa Cell Tumor of the Ovary: A Clinicopathologic Study. J Pediatr Adolesc Gynecol. 2017 Feb; 30(1):138-143.
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FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development. Mol Endocrinol. 2015 Jul; 29(7):1006-24.
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TGF? signaling promotes juvenile granulosa cell tumorigenesis by suppressing apoptosis. Mol Endocrinol. 2014 Nov; 28(11):1887-98.
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Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line. Biol Reprod. 2014 Oct; 91(4):100.
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BMP-specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors. Oncogene. 2013 Aug 15; 32(33):3877-85.