"Granulosa Cell Tumor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
Descriptor ID |
D006106
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MeSH Number(s) |
C04.557.475.750.656 C04.588.322.455.398 C13.351.500.056.630.705.398 C13.351.937.418.685.398 C19.344.410.398 C19.391.630.705.398
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Concept/Terms |
Granulosa Cell Tumor- Granulosa Cell Tumor
- Granulosa Cell Tumors
- Tumor, Granulosa Cell
- Tumors, Granulosa Cell
Granulosa Cell Cancer- Granulosa Cell Cancer
- Cancer, Granulosa Cell
- Cancers, Granulosa Cell
- Cell Cancer, Granulosa
- Cell Cancers, Granulosa
- Granulosa Cell Cancers
- Cancer of Granulosa Cells
- Cells Cancer, Granulosa
- Cells Cancers, Granulosa
- Granulosa Cells Cancer
- Granulosa Cells Cancers
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Below are MeSH descriptors whose meaning is more general than "Granulosa Cell Tumor".
Below are MeSH descriptors whose meaning is more specific than "Granulosa Cell Tumor".
This graph shows the total number of publications written about "Granulosa Cell Tumor" by people in this website by year, and whether "Granulosa Cell Tumor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
1996 | 0 | 1 | 1 |
1999 | 1 | 0 | 1 |
2000 | 1 | 0 | 1 |
2003 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2005 | 2 | 0 | 2 |
2006 | 1 | 0 | 1 |
2007 | 1 | 1 | 2 |
2008 | 2 | 0 | 2 |
2009 | 3 | 1 | 4 |
2011 | 1 | 1 | 2 |
2012 | 1 | 1 | 2 |
2014 | 1 | 1 | 2 |
2015 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2018 | 1 | 2 | 3 |
2019 | 1 | 0 | 1 |
2020 | 1 | 1 | 2 |
2021 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
2023 | 2 | 0 | 2 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Granulosa Cell Tumor" by people in Profiles.
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Serial cytoreductive surgery and survival outcomes in recurrent adult-type ovarian granulosa cell tumors. Am J Obstet Gynecol. 2024 05; 230(5):544.e1-544.e13.
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Comparative Tumor Microenvironment Analysis of Primary and Recurrent Ovarian Granulosa Cell Tumors. Mol Cancer Res. 2023 05 01; 21(5):483-494.
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Clinical outcomes of leuprolide acetate in the treatment of recurrent ovarian granulosa cell tumors. Am J Obstet Gynecol. 2023 06; 228(6):724.e1-724.e9.
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Integrated Analysis of Ovarian Juvenile Granulosa Cell Tumors Reveals Distinct Epigenetic Signatures and Recurrent TERT Rearrangements. Clin Cancer Res. 2022 04 14; 28(8):1724-1733.
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The clinical efficacy and safety of single-agent pembrolizumab in patients with recurrent granulosa cell tumors of the ovary: a case series from a phase II basket trial. Invest New Drugs. 2021 06; 39(3):829-835.
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Differences in gynecologic tumor development in Amhr2-Cre mice with KRASG12D or KRASG12V mutations. Sci Rep. 2020 11 26; 10(1):20678.
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Sex Cord Tumor With Annular Tubules-Like Histologic Pattern in Adult Granulosa Cell Tumor: Case Report of a Hitherto Unreported Morphologic Variant. Int J Surg Pathol. 2021 Jun; 29(4):433-437.
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RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line. Int J Mol Sci. 2019 Jul 15; 20(14).
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Multimodal molecular analysis of an atypical small cell carcinoma of the ovary, hypercalcemic type. Cold Spring Harb Mol Case Stud. 2018 10; 4(5).
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KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary. Nat Commun. 2018 06 27; 9(1):2496.