"Giant Cell Tumor of Bone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bone tumor composed of cellular spindle-cell stroma containing scattered multinucleated giant cells resembling osteoclasts. The tumors range from benign to frankly malignant lesions. The tumor occurs most frequently in an end of a long tubular bone in young adults. (From Dorland, 27th ed; Stedman, 25th ed)
| Descriptor ID |
D018212
|
| MeSH Number(s) |
C04.557.450.565.380.380 C04.557.450.565.575.420
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Giant Cell Tumor of Bone".
Below are MeSH descriptors whose meaning is more specific than "Giant Cell Tumor of Bone".
This graph shows the total number of publications written about "Giant Cell Tumor of Bone" by people in this website by year, and whether "Giant Cell Tumor of Bone" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 |
| 2001 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Giant Cell Tumor of Bone" by people in Profiles.
-
The risk of neurological deterioration while using neoadjuvant denosumab on patients with giant cell tumor of the spine presenting with epidural disease: a meta-analysis of the literature. Spine J. 2024 Jun; 24(6):1056-1064.
-
Response to Denosumab in 2 Children With Recurrent Giant Cell Tumor of the Bone With Pulmonary Metastasis. J Pediatr Hematol Oncol. 2021 03 01; 43(2):e215-e218.
-
H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone. Cancer Discov. 2020 12; 10(12):1968-1987.
-
Comprehensive molecular imaging of malignant transformation of giant cell tumour of bone reveals diverse disease biology. BMJ Case Rep. 2019 Apr 23; 12(4).
-
Histone H3.3 G34 Mutations Alter Histone H3K36 and H3K27 Methylation In Cis. J Mol Biol. 2018 05 25; 430(11):1562-1565.
-
A Large Right Shoulder Mass. JAMA Surg. 2017 07 01; 152(7):701-702.
-
Postpartum Treatment of Metastatic Recurrent Giant Cell Tumor of Capitate Bone of Wrist. Am J Orthop (Belle Mead NJ). 2017 Jul/Aug; 46(4):E269-E275.
-
Giant Cell Tumor of Cervical Spine Presenting as Acute Asphyxia: Successful Surgical Resection After Down-Staging With Denosumab. Spine (Phila Pa 1976). 2017 May 15; 42(10):E629-E632.
-
Benign Tumors of the Spine: Has New Chemotherapy and Interventional Radiology Changed the Treatment Paradigm? Spine (Phila Pa 1976). 2016 Oct 15; 41 Suppl 20:S178-S185.
-
Chemotherapy for bone sarcomas in adults: the MD anderson experience. Am Soc Clin Oncol Educ Book. 2015; e656-60.