Minichromosome Maintenance Complex Component 7
"Minichromosome Maintenance Complex Component 7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It is also found in tightly-bound trimeric complex with MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 4 and MINICHROMOSOME MAINTENANCE COMPLEX COMPONENT 6.
| Descriptor ID |
D064168
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| MeSH Number(s) |
D08.811.277.040.025.159.186.700 D08.811.399.340.186.700 D12.776.167.409.700 D12.776.660.235.500.700 D12.776.664.235.750.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Minichromosome Maintenance Complex Component 7".
Below are MeSH descriptors whose meaning is more specific than "Minichromosome Maintenance Complex Component 7".
This graph shows the total number of publications written about "Minichromosome Maintenance Complex Component 7" by people in this website by year, and whether "Minichromosome Maintenance Complex Component 7" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Minichromosome Maintenance Complex Component 7" by people in Profiles.
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High expression of carbonic anhydrase IX is significantly associated with glandular lesions in gastroesophageal junction and with tumorigenesis markers BMI1, MCM4 and MCM7. BMC Gastroenterol. 2015 Jul 09; 15:80.
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Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers. Cancer Cell. 2013 Jun 10; 23(6):796-810.
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Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions. J Biol Chem. 2010 Jul 23; 285(30):23457-65.
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Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation. Sci Signal. 2010 Apr 13; 3(117):ra29.
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E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell. 2008 Mar; 13(3):272-86.
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Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis. Oncogene. 2006 Jul 06; 25(29):4027-32.
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Direct interaction between cohesin complex and DNA replication machinery. Biochem Biophys Res Commun. 2006 Mar 17; 341(3):770-5.
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Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases. Proc Natl Acad Sci U S A. 2004 Jul 06; 101(27):10078-83.
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The cyclin D1-dependent kinase associates with the pre-replication complex and modulates RB.MCM7 binding. J Biol Chem. 2003 Mar 14; 278(11):9754-60.
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Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma. Cancer Res. 2002 Feb 15; 62(4):1123-8.