Minichromosome Maintenance Complex Component 2
"Minichromosome Maintenance Complex Component 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A minichromosome maintenance protein that is a key component of the six member MCM protein complex. It contains a NUCLEAR LOCALIZATION SIGNAL which may provide targeting of the protein complex and an extended N-terminus which is rich in SERINE residues.
| Descriptor ID |
D064111
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| MeSH Number(s) |
D08.811.277.040.025.159.186.200 D08.811.399.340.186.200 D12.776.167.409.200 D12.776.660.235.500.200 D12.776.664.235.750.200
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| Concept/Terms |
Minichromosome Maintenance Complex Component 2- Minichromosome Maintenance Complex Component 2
- Minichromosome Maintenance Protein 2 Homolog
- Nuclear Protein BM28
- BM28, Nuclear Protein
- Protein BM28, Nuclear
- DNA Replication Licensing Factor MCM2
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Below are MeSH descriptors whose meaning is more general than "Minichromosome Maintenance Complex Component 2".
Below are MeSH descriptors whose meaning is more specific than "Minichromosome Maintenance Complex Component 2".
This graph shows the total number of publications written about "Minichromosome Maintenance Complex Component 2" by people in this website by year, and whether "Minichromosome Maintenance Complex Component 2" was a major or minor topic of these publications.
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Below are the most recent publications written about "Minichromosome Maintenance Complex Component 2" by people in Profiles.
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Human cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis. PLoS Pathog. 2010 Mar 19; 6(3):e1000814.
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Comparison of ProEx C with p16INK4a and Ki-67 immunohistochemical staining of cell blocks prepared from residual liquid-based cervicovaginal material: a pilot study. Cancer. 2008 Dec 25; 114(6):474-80.
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A novel MCM-2 fragment with potential biological function in senescence. Cell Cycle. 2008 Nov 15; 7(22):3480.
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Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer. BMC Cancer. 2006 Aug 01; 6:203.
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Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases. Proc Natl Acad Sci U S A. 2004 Jul 06; 101(27):10078-83.
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MCM2 is an independent predictor of survival in patients with non-small-cell lung cancer. J Clin Oncol. 2001 Nov 15; 19(22):4259-66.
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MCM2--a promising marker for premalignant lesions of the lung: a cohort study. BMC Cancer. 2001; 1:6.