Receptors, Purinergic P2X7
"Receptors, Purinergic P2X7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purinergic P2X neurotransmitter receptor that plays a role in pain sensation signaling and regulation of inflammatory processes.
| Descriptor ID |
D058486
|
| MeSH Number(s) |
D12.776.157.530.400.400.750.700 D12.776.543.550.450.500.600.700 D12.776.543.585.400.500.600.700 D12.776.543.750.695.700.720.250.700 D12.776.543.750.720.700.720.500.700
|
| Concept/Terms |
Receptors, Purinergic P2X7- Receptors, Purinergic P2X7
- P2X7 Receptors, Purinergic
- Purinergic P2X7 Receptors
- P2X7 Receptor
- P2X7 Purinoceptor
- Purinoceptor, P2X7
- P2Z Receptor
- Purinoceptor P2Z
- P2Z, Purinoceptor
- P2X7 Purinoceptors
- Purinoceptors, P2X7
- Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2X7".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
- Receptors, Purinergic P2X7 [D12.776.157.530.400.400.750.700]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Receptors, Purinergic P2X [D12.776.543.550.450.500.600]
- Receptors, Purinergic P2X7 [D12.776.543.550.450.500.600.700]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
- Receptors, Purinergic P2X7 [D12.776.543.585.400.500.600.700]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.695.700.720.250]
- Receptors, Purinergic P2X7 [D12.776.543.750.695.700.720.250.700]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
- Receptors, Purinergic P2X7 [D12.776.543.750.720.700.720.500.700]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2X7".
This graph shows the total number of publications written about "Receptors, Purinergic P2X7" by people in this website by year, and whether "Receptors, Purinergic P2X7" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptors, Purinergic P2X7" by people in Profiles.
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P2X7R-primed keratinocytes are susceptible to apoptosis via GPCR-G??-pERK signal pathways. J Dermatol Sci. 2024 Dec; 116(3):90-99.
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Localized inhibition of P2X7R at the spinal cord injury site improves neurogenic bladder dysfunction by decreasing urothelial P2X3R expression in rats. Life Sci. 2017 Feb 15; 171:60-67.
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Deletion of P2X7 attenuates hyperoxia-induced acute lung injury via inflammasome suppression. Am J Physiol Lung Cell Mol Physiol. 2016 Mar 15; 310(6):L572-81.
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Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans. J Clin Endocrinol Metab. 2015 May; 100(5):E688-96.
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P2X7 signaling promotes microsphere embolism-triggered microglia activation by maintaining elevation of Fas ligand. J Neuroinflammation. 2012 Jul 12; 9:172.
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Expression and function of P2X(7) receptor and CD39/Entpd1 in patients with type 2 diabetes and their association with biochemical parameters. Cell Immunol. 2011; 269(2):135-43.
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Discovery on Target 2007--CHI's Fifth Annual Conference. Ion channels. IDrugs. 2007 Dec; 10(12):851-4.
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In vitro and in vivo evidence for a role of the P2X7 receptor in the release of IL-1 beta in the murine brain. Brain Behav Immun. 2008 Feb; 22(2):234-44.
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P2X7 polymorphism and chronic lymphocytic leukaemia. Lancet. 2003 Apr 26; 361(9367):1478; author reply 1478-9.
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Cutting edge: purinergic signaling regulates radical-mediated bacterial killing mechanisms in macrophages through a P2X7-independent mechanism. J Immunol. 1999 Jul 15; 163(2):558-61.