"Post-Synaptic Density" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytoskeleton specialization at the cytoplasmic side of postsynaptic membrane in SYNAPSES. It is involved in neuronal signaling and NEURONAL PLASTICITY and comprised of GLUTAMATE RECEPTORS; scaffolding molecules (e.g., PSD95, PSD93), and other proteins (e.g., CaCMKII).
| Descriptor ID |
D057907
|
| MeSH Number(s) |
A08.850.800.500 A11.284.149.165.420.780.800.500
|
| Concept/Terms |
Post-Synaptic Density- Post-Synaptic Density
- Post Synaptic Density
- Post-Synaptic Densities
- Postsynaptic Density Region
- Postsynaptic Density Regions
- Region, Postsynaptic Density
- Regions, Postsynaptic Density
- Post-Synaptic Density Region
- Post Synaptic Density Region
- Post-Synaptic Density Regions
- Region, Post-Synaptic Density
- Regions, Post-Synaptic Density
- Postsynaptic Density
- Postsynaptic Densities
|
Below are MeSH descriptors whose meaning is more general than "Post-Synaptic Density".
Below are MeSH descriptors whose meaning is more specific than "Post-Synaptic Density".
This graph shows the total number of publications written about "Post-Synaptic Density" by people in this website by year, and whether "Post-Synaptic Density" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 2 | 1 | 3 |
| 2019 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Post-Synaptic Density" by people in Profiles.
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Post-ischemic ubiquitination at the postsynaptic density reversibly influences the activity of ischemia-relevant kinases. Commun Biol. 2024 Mar 13; 7(1):321.
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An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function. Mol Psychiatry. 2020 10; 25(10):2534-2555.
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Gene Disrupting Mutations Associated with Regression in Autism Spectrum Disorder. J Autism Dev Disord. 2017 Nov; 47(11):3600-3607.
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The calcium sensor synaptotagmin 1 is expressed and regulated in hippocampal postsynaptic spines. Hippocampus. 2017 11; 27(11):1168-1177.
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The KIF1A homolog Unc-104 is important for spontaneous release, postsynaptic density maturation and perisynaptic scaffold organization. Sci Rep. 2017 03 27; 7:38172.
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Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction. Mol Psychiatry. 2013 Oct; 18(10):1077-89.
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Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission. J Neurosci. 2012 Nov 07; 32(45):16018-30.