Zinc finger domains of approximately 50 to 80 amino acids in length that are characterized by a conserved Cysteine(3)-Histidine-Cysteine(4) amino acid motif which coordinates binding of two zinc ions. They are similar structurally to RING FINGER DOMAINS, with a globular fold topology of two BETA-SHEETS and an ALPHA-HELIX. PHD fingers occur in many proteins that function in chromatin-mediated gene expression and EPIGENETICS such as POLYCOMB-GROUP PROTEINS.

Descriptor ID	D000075925
MeSH Number(s)	G02.111.570.820.709.275.500.985.438
Concept/Terms	PHD Zinc Fingers PHD Zinc Fingers Finger, PHD Zinc Fingers, PHD Zinc Zinc Finger, PHD Zinc Fingers, PHD PHD Fingers Finger, PHD Fingers, PHD PHD Finger PHD Motifs PHD Domains Domain, PHD Domains, PHD PHD Domain PHD Zinc Finger PHD Finger Domain Domain, PHD Finger Domains, PHD Finger Finger Domain, PHD Finger Domains, PHD PHD Finger Domains PHD Motif Motif, PHD Motifs, PHD

Below are MeSH descriptors whose meaning is more general than "PHD Zinc Fingers".

Below are MeSH descriptors whose meaning is related to "PHD Zinc Fingers".

Below are MeSH descriptors whose meaning is more specific than "PHD Zinc Fingers".