"Perilipin-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A perilipin that localizes to LIPID DROPLETS; CYTOPLASM; ENDOSOMES; and PLASMA MEMBRANE, especially in MACROPHAGES. It functions as a transporter of free fatty acids to lipid droplets to promote their biogenesis and growth. It is also required for the transport of the MANNOSE-6-PHOSPHATE RECEPTOR from endosomes to the TRANS-GOLGI NETWORK. Its structure consists of four helix bundles that interact with the hydrophobic lipid droplet surface.
| Descriptor ID |
D000070796
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| MeSH Number(s) |
D12.776.157.464.500.875
|
| Concept/Terms |
Perilipin-3- Perilipin-3
- Perilipin 3
- TIP47 Protein
- Protein, TIP47
- 47 kDa Mannose 6-Phosphate Receptor-Binding Protein
- 47 kDa Mannose 6 Phosphate Receptor Binding Protein
- Tail Interacting Protein of 47 kDa
- 47 kDa MPR-binding Protein
- 47 kDa MPR binding Protein
- Cargo Selection Protein TIP47
- Placental Protein 17
- Mannose-6-Phosphate Receptor-Binding Protein 1
- Mannose 6 Phosphate Receptor Binding Protein 1
- PLIN3 Protein
- Protein, PLIN3
- Perilipin 3 Protein
- Protein, Perilipin 3
|
Below are MeSH descriptors whose meaning is more general than "Perilipin-3".
Below are MeSH descriptors whose meaning is more specific than "Perilipin-3".
This graph shows the total number of publications written about "Perilipin-3" by people in this website by year, and whether "Perilipin-3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Perilipin-3" by people in Profiles.
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Phosphorylation of PLIN3 by AMPK promotes dispersion of lipid droplets during starvation. Protein Cell. 2019 05; 10(5):382-387.
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Absence of adipose differentiation related protein upregulates hepatic VLDL secretion, relieves hepatosteatosis, and improves whole body insulin resistance in leptin-deficient mice. J Lipid Res. 2010 Aug; 51(8):2132-42.
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Coatomer-dependent protein delivery to lipid droplets. J Cell Sci. 2009 Jun 01; 122(Pt 11):1834-41.
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Deficiency of adipose differentiation-related protein impairs foam cell formation and protects against atherosclerosis. Circ Res. 2008 Jun 20; 102(12):1492-501.