"Perilipin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.
| Descriptor ID |
D000070780
|
| MeSH Number(s) |
D12.776.157.464.500.750
|
| Concept/Terms |
Perilipin-2- Perilipin-2
- Perilipin 2
- ADRP Protein
- Adipose Differentiation-Related Protein
- Adipose Differentiation Related Protein
- Protein, Adipose Differentiation-Related
- PLIN2 Protein
- Protein, PLIN2
- Perilipin 2 Protein
- Protein, Perilipin 2
- Adipophilin
|
Below are MeSH descriptors whose meaning is more general than "Perilipin-2".
Below are MeSH descriptors whose meaning is more specific than "Perilipin-2".
This graph shows the total number of publications written about "Perilipin-2" by people in this website by year, and whether "Perilipin-2" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 3 | 3 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Perilipin-2" by people in Profiles.
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HPV-associated Vulvar Intraepithelial Carcinoma With Sebaceous Differentiation: Report of 2 Cases. Int J Gynecol Pathol. 2023 Jul 01; 42(4):338-346.
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Thymic epithelial neoplasms with sebaceous differentiation: a clinicopathological and immunohistochemical study of 8 cases. Hum Pathol. 2019 04; 86:124-128.
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Immunohistochemical markers informing the diagnosis of sebaceous carcinoma and its distinction from its mimics: Adipophilin and factor XIIIa to the rescue? J Cutan Pathol. 2018 01; 45(1):29-32.
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The constitutive lipid droplet protein PLIN2 regulates autophagy in liver. Autophagy. 2017 Jul 03; 13(7):1130-1144.
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PLIN2 is a Key Regulator of the Unfolded Protein Response and Endoplasmic Reticulum Stress Resolution in Pancreatic ? Cells. Sci Rep. 2017 01 19; 7:40855.
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Enhanced atheroprotection and lesion remodelling by targeting the foam cell and increasing plasma cholesterol acceptors. Cardiovasc Res. 2016 Feb 01; 109(2):294-304.
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S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease. J Hepatol. 2015 Mar; 62(3):673-81.
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Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis. Hepatology. 2013 Oct; 58(4):1296-305.
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Delayed liver regeneration after partial hepatectomy in adipose differentiation related protein-null mice. J Hepatol. 2013 Dec; 59(6):1246-54.
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PLIN2, the major perilipin regulated during sebocyte differentiation, controls sebaceous lipid accumulation in vitro and sebaceous gland size in vivo. Biochim Biophys Acta. 2013 Oct; 1830(10):4642-9.