"Duloxetine Hydrochloride" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A thiophene derivative and selective NEUROTRANSMITTER UPTAKE INHIBITOR for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC, and is also used for the treatment of pain in patients with DIABETES MELLITUS and FIBROMYALGIA.
| Descriptor ID |
D000068736
|
| MeSH Number(s) |
D02.886.778.260 D03.383.903.260
|
| Concept/Terms |
Duloxetine- Duloxetine
- N-methyl-3-(1-naphthalenyloxy)-3-(2-thiophene)propanamide
- N-methyl-3-(1-naphthalenyloxy)-2-thiophenepropanamine
|
Below are MeSH descriptors whose meaning is more general than "Duloxetine Hydrochloride".
Below are MeSH descriptors whose meaning is more specific than "Duloxetine Hydrochloride".
This graph shows the total number of publications written about "Duloxetine Hydrochloride" by people in this website by year, and whether "Duloxetine Hydrochloride" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Duloxetine Hydrochloride" by people in Profiles.
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MALDI Imaging Mass Spectrometry Visualizes the Distribution of Antidepressant Duloxetine and Its Major Metabolites in Mouse Brain, Liver, Kidney, and Spleen Tissues. Drug Metab Dispos. 2024 Jun 17; 52(7):673-680.
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Comparative effectiveness research trial for antidepressant incomplete and non-responders with treatment resistant depression (ASCERTAIN-TRD) a randomized clinical trial. Mol Psychiatry. 2024 Aug; 29(8):2287-2295.
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Duloxetine and Amitriptyline Reduce Neuropathic Pain by Inhibiting Primary Sensory Input to Spinal Dorsal Horn Neurons via a1- and a2-Adrenergic Receptors. ACS Chem Neurosci. 2023 04 05; 14(7):1261-1277.
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The roles of Cyp1a2 and Cyp2d in pharmacokinetic profiles of serotonin and norepinephrine reuptake inhibitor duloxetine and its metabolites in mice. Eur J Pharm Sci. 2023 Feb 01; 181:106358.
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Hyponatremia with Antidepressant: A Rare Side Effect from Duloxetine in a Child with Acute Leukemia. J Palliat Med. 2022 12; 25(12):1884-1887.
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Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice. Drug Metab Dispos. 2022 02; 50(2):128-139.
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Current use of drugs affecting the central nervous system for chemotherapy-induced peripheral neuropathy in cancer patients: a systematic review. Support Care Cancer. 2015 Feb; 23(2):513-24.
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Duloxetine, a serotonin and noradrenaline reuptake inhibitor (SNRI) for the treatment of stress urinary incontinence: a systematic review. Eur Urol. 2007 Jan; 51(1):67-74.
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The combination of duloxetine and bupropion for treatment-resistant major depressive disorder. Depress Anxiety. 2006; 23(3):178-81.
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Serotonin and noradrenaline reuptake inhibitors (SNRI) for stress urinary incontinence in adults. Cochrane Database Syst Rev. 2005 Jul 20; (3):CD004742.