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RUI CHEN

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Human Genetics
AddressOne Baylor Plaza, 231e
Houston, 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Biochemistry and Molecular Pharmacology
    DivisionBiochemistry & Mol Pharmacology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentHuman Genome Sequencing Center
    DivisionHuman Genome Sequencing Center


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    UM1DA058229     (GIBBS, RICHARD A)May 1, 2023 - Apr 30, 2028
    NIH
    Comprehensive Somatic Variant Characterization at the HGSC
    Role: Co-Principal Investigator
    U01EY034692     (PFLUGFELDER, STEPHEN C)Sep 30, 2022 - Aug 31, 2027
    NIH
    Effects of cornea epithelial barrier disruption on the cornea trigeminal neural circuit
    Role: Co-Principal Investigator
    R01EY032768     (ZHI, DEGUI)Sep 30, 2022 - Jun 30, 2025
    NIH
    Deep-Learning-Derived Endophenotypes from Retina Images
    Role: Co-Principal Investigator
    R33NS115102     (EMBORG, MARINA)Sep 30, 2019 - May 31, 2025
    NIH
    Modeling Frontotemporal Dementia in Rhesus Macaques
    Role: Co-Principal Investigator
    R61NS115102     (EMBORG, MARINA)Sep 30, 2019 - May 31, 2021
    NIH
    Modeling Frontotemporal Dementia in Rhesus Macaques
    Role: Co-Principal Investigator
    U24EY029904     (CHEN, RUI ;ROGERS, JEFFREY A. ;STOUT, JOHN T;THOMASY, SARA MICHELLE)Sep 30, 2018 - Aug 31, 2024
    NIH
    Novel model systems for the study of cone disorders and other heritable retinal diseases
    Role: Co-Principal Investigator
    S10OD023469     (CHEN, RUI)Sep 1, 2017 - Aug 31, 2018
    NIH
    High Throughput Genomic Sequencer at BCM Core Facility
    Role: Principal Investigator
    R01EY026045     (STOUT, JOHN T)Mar 1, 2016 - Feb 28, 2022
    NIH
    Animal Models of Ocular Disease
    Role: Co-Principal Investigator
    S10OD018033     (CHEN, RUI)Jul 15, 2014 - Jul 14, 2015
    NIH
    Acquisition of the Fluidigm system to accelerate functional genomics research
    Role: Principal Investigator
    R01EY022356     (CHEN, RUI)Jun 1, 2012 - May 31, 2029
    NIH
    Molecular Basis of Human Visual System Disorders
    Role: Principal Investigator
    R01EY020540     (MARDON, GRAEME)Feb 1, 2011 - Sep 29, 2018
    NIH
    Molecular Mechanisms of Human Retinal Disease
    Role: Co-Principal Investigator
    S10RR026550     (CHEN, RUI)Jun 10, 2010 - Sep 9, 2011
    NIH
    FGI: Acquisition of an Illumina Genome Analyzer System for Functional Genomic Res
    Role: Principal Investigator
    R01EY018571     (CHEN, RUI)Dec 1, 2007 - Jul 31, 2026
    NIH
    GENETICS OF EARLY ONSET RETINAL DISEASES
    Role: Principal Investigator
    R01EY016853     (CHEN, RUI)Aug 1, 2005 - May 31, 2011
    NIH
    Genome-wide Dissection of the Retinal Determination Network
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Soens ZT, Li Y, Zhao L, Eblimit A, Dharmat R, Li Y, Chen Y, Naqeeb M, Fajardo N, Lopez I, Sun Z, Koenekoop RK, Chen R. Hypomorphic mutations identified in the candidate Leber congenital amaurosis gene CLUAP1. Genet Med. 2016 10; 18(10):1044-51. PMID: 26820066; PMCID: PMC4965339.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    2. Xu M, Eblimit A, Wang J, Li J, Wang F, Zhao L, Wang X, Xiao N, Li Y, Wong LJ, Lewis RA, Chen R. ADIPOR1 Is Mutated in Syndromic Retinitis Pigmentosa. Hum Mutat. 2016 Mar; 37(3):246-9. PMID: 26662040; PMCID: PMC5383450.
      Citations: 23     Fields:    Translation:HumansAnimals
    3. Xu M, Yang L, Wang F, Li H, Wang X, Wang W, Ge Z, Wang K, Zhao L, Li H, Li Y, Sui R, Chen R. Mutations in human IFT140 cause non-syndromic retinal degeneration. Hum Genet. 2015 Oct; 134(10):1069-78. PMID: 26216056; PMCID: PMC4565766.
      Citations: 29     Fields:    Translation:HumansCells
    4. Sheng X, Chen X, Lei B, Chen R, Wang H, Zhang F, Rong W, Ha R, Liu Y, Zhao F, Yang P, Zhao C. Whole exome sequencing confirms the clinical diagnosis of Marfan syndrome combined with X-linked hypophosphatemia. J Transl Med. 2015 Jun 04; 13:179. PMID: 26040324; PMCID: PMC4455986.
      Citations: 1     Fields:    Translation:HumansCells
    5. Xu M, Gelowani V, Eblimit A, Wang F, Young MP, Sawyer BL, Zhao L, Jenkins G, Creel DJ, Wang K, Ge Z, Wang H, Li Y, Hartnett ME, Chen R. ATF6 Is Mutated in Early Onset Photoreceptor Degeneration With Macular Involvement. Invest Ophthalmol Vis Sci. 2015 Jun; 56(6):3889-95. PMID: 26070061; PMCID: PMC4468593.
      Citations: 29     Fields:    Translation:HumansCells
    6. Wang H, Wang X, Zou X, Xu S, Li H, Soens ZT, Wang K, Li Y, Dong F, Chen R, Sui R. Comprehensive Molecular Diagnosis of a Large Chinese Leber Congenital Amaurosis Cohort. Invest Ophthalmol Vis Sci. 2015 Jun; 56(6):3642-55. PMID: 26047050; PMCID: PMC4466882.
      Citations: 37     Fields:    Translation:Humans
    7. Mazur EC, Vasquez YM, Li X, Kommagani R, Jiang L, Chen R, Lanz RB, Kovanci E, Gibbons WE, DeMayo FJ. Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells. Endocrinology. 2015 Jun; 156(6):2239-53. PMID: 25781565; PMCID: PMC4430623.
      Citations: 39     Fields:    Translation:HumansCells
    8. Salvo J, Lyubasyuk V, Xu M, Wang H, Wang F, Nguyen D, Wang K, Luo H, Wen C, Shi C, Lin D, Zhang K, Chen R. Next-generation sequencing and novel variant determination in a cohort of 92 familial exudative vitreoretinopathy patients. Invest Ophthalmol Vis Sci. 2015 Feb 24; 56(3):1937-46. PMID: 25711638; PMCID: PMC4365990.
      Citations: 39     Fields:    Translation:Humans
    9. Zhong H, Chen Y, Li Y, Chen R, Mardon G. CRISPR-engineered mosaicism rapidly reveals that loss of Kcnj13 function in mice mimics human disease phenotypes. Sci Rep. 2015 Feb 10; 5:8366. PMID: 25666713; PMCID: PMC4322368.
      Citations: 56     Fields:    Translation:HumansAnimals
    10. Zhao L, Wang F, Wang H, Li Y, Alexander S, Wang K, Willoughby CE, Zaneveld JE, Jiang L, Soens ZT, Earle P, Simpson D, Silvestri G, Chen R. Next-generation sequencing-based molecular diagnosis of 82 retinitis pigmentosa probands from Northern Ireland. Hum Genet. 2015 Feb; 134(2):217-30. PMID: 25472526; PMCID: PMC4347882.
      Citations: 54     Fields:    Translation:HumansCTClinical Trials
    11. Zaneveld J, Siddiqui S, Li H, Wang X, Wang H, Wang K, Li H, Ren H, Lopez I, Dorfman A, Khan A, Wang F, Salvo J, Gelowani V, Li Y, Sui R, Koenekoop R, Chen R. Comprehensive analysis of patients with Stargardt macular dystrophy reveals new genotype-phenotype correlations and unexpected diagnostic revisions. Genet Med. 2015 Apr; 17(4):262-70. PMID: 25474345; PMCID: PMC4385427.
      Citations: 22     Fields:    Translation:Humans
    12. Wang F, Li H, Xu M, Li H, Zhao L, Yang L, Zaneveld JE, Wang K, Li Y, Sui R, Chen R. A homozygous missense mutation in NEUROD1 is associated with nonsyndromic autosomal recessive retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2014 Dec 04; 56(1):150-5. PMID: 25477324; PMCID: PMC4290556.
      Citations: 12     Fields:    Translation:Humans
    13. Jusiak B, Wang F, Karandikar UC, Kwak SJ, Wang H, Chen R, Mardon G. Genome-wide DNA binding pattern of the homeodomain transcription factor Sine oculis (So) in the developing eye of Drosophila melanogaster. Genom Data. 2014 Dec 01; 2:153-155. PMID: 25126519; PMCID: PMC4128500.
      Citations: 10     
    14. Eblimit A, Nguyen TM, Chen Y, Esteve-Rudd J, Zhong H, Letteboer S, Van Reeuwijk J, Simons DL, Ding Q, Wu KM, Li Y, Van Beersum S, Moayedi Y, Xu H, Pickard P, Wang K, Gan L, Wu SM, Williams DS, Mardon G, Roepman R, Chen R. Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina. Hum Mol Genet. 2015 Mar 15; 24(6):1584-601. PMID: 25398945; PMCID: PMC4351378.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    15. Wang F, Wang Y, Zhang B, Zhao L, Lyubasyuk V, Wang K, Xu M, Li Y, Wu F, Wen C, Bernstein PS, Lin D, Zhu S, Wang H, Zhang K, Chen R. A missense mutation in HK1 leads to autosomal dominant retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2014 Oct 14; 55(11):7159-64. PMID: 25316723; PMCID: PMC4224578.
      Citations: 11     Fields:    Translation:Humans
    16. Haelterman NA, Jiang L, Li Y, Bayat V, Sandoval H, Ugur B, Tan KL, Zhang K, Bei D, Xiong B, Charng WL, Busby T, Jawaid A, David G, Jaiswal M, Venken KJ, Yamamoto S, Chen R, Bellen HJ. Large-scale identification of chemically induced mutations in Drosophila melanogaster. Genome Res. 2014 Oct; 24(10):1707-18. PMID: 25258387; PMCID: PMC4199363.
      Citations: 40     Fields:    Translation:AnimalsCells
    17. Yamamoto S, Jaiswal M, Charng WL, Gambin T, Karaca E, Mirzaa G, Wiszniewski W, Sandoval H, Haelterman NA, Xiong B, Zhang K, Bayat V, David G, Li T, Chen K, Gala U, Harel T, Pehlivan D, Penney S, Vissers LELM, de Ligt J, Jhangiani SN, Xie Y, Tsang SH, Parman Y, Sivaci M, Battaloglu E, Muzny D, Wan YW, Liu Z, Lin-Moore AT, Clark RD, Curry CJ, Link N, Schulze KL, Boerwinkle E, Dobyns WB, Allikmets R, Gibbs RA, Chen R, Lupski JR, Wangler MF, Bellen HJ. A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases. Cell. 2014 Sep 25; 159(1):200-214. PMID: 25259927; PMCID: PMC4298142.
      Citations: 168     Fields:    Translation:HumansAnimalsCells
    18. Bejar R, Lord A, Stevenson K, Bar-Natan M, Zaneveld J, Wang H, Caughey B, Stojanov P, Getz G, Garcia-Manero G, Kantarjian H, Chen R, Stone RM, Neuberg D, Steensma DP, Ebert BL, P?rez-Ladaga A. TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients. Blood. 2014 Oct 23; 124(17):2705-12. PMID: 25224413; PMCID: PMC4208285.
      Citations: 229     Fields:    Translation:HumansAnimalsCells
    19. Tao J, Jiang MM, Jiang L, Salvo JS, Zeng HC, Dawson B, Bertin TK, Rao PH, Chen R, Donehower LA, Gannon F, Lee BH. Notch activation as a driver of osteogenic sarcoma. Cancer Cell. 2014 Sep 08; 26(3):390-401. PMID: 25203324; PMCID: PMC4159617.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    20. Karandikar UC, Jin M, Jusiak B, Kwak S, Chen R, Mardon G. Drosophila eyes absent is required for normal cone and pigment cell development. PLoS One. 2014; 9(7):e102143. PMID: 25057928; PMCID: PMC4109927.
      Citations: 12     Fields:    Translation:AnimalsCells
    21. Sun D, Luo M, Jeong M, Rodriguez B, Xia Z, Hannah R, Wang H, Le T, Faull KF, Chen R, Gu H, Bock C, Meissner A, Darlington GJ, Li W, Goodell MA, G?ttgens B. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell. 2014 May 01; 14(5):673-88. PMID: 24792119; PMCID: PMC4070311.
      Citations: 256     Fields:    Translation:AnimalsCells
    22. Jusiak B, Karandikar UC, Kwak SJ, Wang F, Wang H, Chen R, Mardon G. Regulation of Drosophila eye development by the transcription factor Sine oculis. PLoS One. 2014; 9(2):e89695. PMID: 24586968; PMCID: PMC3934907.
      Citations: 19     Fields:    Translation:Animals
    23. Kunde-Ramamoorthy G, Coarfa C, Laritsky E, Kessler NJ, Harris RA, Xu M, Chen R, Shen L, Milosavljevic A, Waterland RA. Comparison and quantitative verification of mapping algorithms for whole-genome bisulfite sequencing. Nucleic Acids Res. 2014 Apr; 42(6):e43. PMID: 24391148; PMCID: PMC3973287.
      Citations: 29     Fields:    Translation:HumansCells
    24. Jeong M, Sun D, Luo M, Huang Y, Challen GA, Rodriguez B, Zhang X, Chavez L, Wang H, Hannah R, Kim SB, Yang L, Ko M, Chen R, Lee JS, Gunaratne P, Godley LA, Darlington GJ, Rao A, Li W, Goodell MA, G?ttgens B. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nat Genet. 2014 Jan; 46(1):17-23. PMID: 24270360; PMCID: PMC3920905.
      Citations: 164     Fields:    Translation:HumansAnimalsCells
    25. Zhou Q, Zhang T, Jemc JC, Chen Y, Chen R, Rebay I, Pignoni F. Onset of atonal expression in Drosophila retinal progenitors involves redundant and synergistic contributions of Ey/Pax6 and So binding sites within two distant enhancers. Dev Biol. 2014 Feb 01; 386(1):152-64. PMID: 24247006; PMCID: PMC5223736.
      Citations: 11     Fields:    Translation:AnimalsCells
    26. Wang F, Wang H, Tuan HF, Nguyen DH, Sun V, Keser V, Bowne SJ, Sullivan LS, Luo H, Zhao L, Wang X, Zaneveld JE, Salvo JS, Siddiqui S, Mao L, Wheaton DK, Birch DG, Branham KE, Heckenlively JR, Wen C, Flagg K, Ferreyra H, Pei J, Khan A, Ren H, Wang K, Lopez I, Qamar R, Zenteno JC, Ayala-Ramirez R, Buentello-Volante B, Fu Q, Simpson DA, Li Y, Sui R, Silvestri G, Daiger SP, Koenekoop RK, Zhang K, Chen R. Next generation sequencing-based molecular diagnosis of retinitis pigmentosa: identification of a novel genotype-phenotype correlation and clinical refinements. Hum Genet. 2014 Mar; 133(3):331-45. PMID: 24154662; PMCID: PMC3945441.
      Citations: 119     Fields:    Translation:Humans
    27. Wang X, Wang H, Sun V, Tuan HF, Keser V, Wang K, Ren H, Lopez I, Zaneveld JE, Siddiqui S, Bowles S, Khan A, Salvo J, Jacobson SG, Iannaccone A, Wang F, Birch D, Heckenlively JR, Fishman GA, Traboulsi EI, Li Y, Wheaton D, Koenekoop RK, Chen R. Comprehensive molecular diagnosis of 179 Leber congenital amaurosis and juvenile retinitis pigmentosa patients by targeted next generation sequencing. J Med Genet. 2013 Oct; 50(10):674-88. PMID: 23847139; PMCID: PMC3932025.
      Citations: 72     Fields:    Translation:HumansCells
    28. Li Y, Jiang Y, Chen Y, Karandikar U, Hoffman K, Chattopadhyay A, Mardon G, Chen R. optix functions as a link between the retinal determination network and the dpp pathway to control morphogenetic furrow progression in Drosophila. Dev Biol. 2013 Sep 01; 381(1):50-61. PMID: 23792115; PMCID: PMC3742619.
      Citations: 8     Fields:    Translation:AnimalsCells
    29. Nasser W, Santhanam B, Miranda ER, Parikh A, Juneja K, Rot G, Dinh C, Chen R, Zupan B, Shaulsky G, Kuspa A. Bacterial discrimination by dictyostelid amoebae reveals the complexity of ancient interspecies interactions. Curr Biol. 2013 May 20; 23(10):862-72. PMID: 23664307; PMCID: PMC3914002.
      Citations: 32     Fields:    Translation:AnimalsCells
    30. Haase Gilbert E, Kwak SJ, Chen R, Mardon G. Drosophila signal peptidase complex member Spase12 is required for development and cell differentiation. PLoS One. 2013; 8(4):e60908. PMID: 23573290; PMCID: PMC3616019.
      Citations: 3     Fields:    Translation:Animals
    31. Huang Z, Chen K, Zhang J, Li Y, Wang H, Cui D, Tang J, Liu Y, Shi X, Li W, Liu D, Chen R, Sucgang RS, Pan X. A functional variomics tool for discovering drug-resistance genes and drug targets. Cell Rep. 2013 Feb 21; 3(2):577-85. PMID: 23416056; PMCID: PMC3594652.
      Citations: 32     Fields:    Translation:Animals
    32. Zaneveld J, Wang F, Wang X, Chen R. Dawn of ocular gene therapy: implications for molecular diagnosis in retinal disease. Sci China Life Sci. 2013 Feb; 56(2):125-33. PMID: 23393028; PMCID: PMC3567286.
      Citations: 4     Fields:    Translation:HumansAnimals
    33. Jusiak B, Abulimiti A, Haelterman N, Chen R, Mardon G. MAPK target sites of eyes absent are not required for eye development or survival in Drosophila. PLoS One. 2012; 7(12):e50776. PMID: 23251383; PMCID: PMC3520925.
      Citations: 7     Fields:    Translation:AnimalsCells
    34. Kriel A, Bittner AN, Kim SH, Liu K, Tehranchi AK, Zou WY, Rendon S, Chen R, Tu BP, Wang JD. Direct regulation of GTP homeostasis by (p)ppGpp: a critical component of viability and stress resistance. Mol Cell. 2012 Oct 26; 48(2):231-41. PMID: 22981860; PMCID: PMC3483369.
      Citations: 138     Fields:    Translation:HumansCells
    35. Wang H, Chen X, Dudinsky L, Patenia C, Chen Y, Li Y, Wei Y, Abboud EB, Al-Rajhi AA, Lewis RA, Lupski JR, Mardon G, Gibbs RA, Perkins BD, Chen R. Exome capture sequencing identifies a novel mutation in BBS4. Mol Vis. 2011; 17:3529-40. PMID: 22219648; PMCID: PMC3250376.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    36. Wang X, Wang H, Cao M, Li Z, Chen X, Patenia C, Gore A, Abboud EB, Al-Rajhi AA, Lewis RA, Lupski JR, Mardon G, Zhang K, Muzny D, Gibbs RA, Chen R. Whole-exome sequencing identifies ALMS1, IQCB1, CNGA3, and MYO7A mutations in patients with Leber congenital amaurosis. Hum Mutat. 2011 Dec; 32(12):1450-9. PMID: 21901789; PMCID: PMC3943164.
      Citations: 32     Fields:    Translation:Humans
    37. Malovannaya A, Lanz RB, Jung SY, Bulynko Y, Le NT, Chan DW, Ding C, Shi Y, Yucer N, Krenciute G, Kim BJ, Li C, Chen R, Li W, Wang Y, O'Malley BW, Qin J. Analysis of the human endogenous coregulator complexome. Cell. 2011 May 27; 145(5):787-99. PMID: 21620140; PMCID: PMC3131083.
      Citations: 207     Fields:    Translation:HumansCells
    38. Yang D, Xiong Y, Kim H, He Q, Li Y, Chen R, Songyang Z. Human telomeric proteins occupy selective interstitial sites. Cell Res. 2011 Jul; 21(7):1013-27. PMID: 21423278; PMCID: PMC3193500.
      Citations: 80     Fields:    Translation:HumansCells
    39. Xi Y, Yao J, Chen R, Li W, He X. Nucleosome fragility reveals novel functional states of chromatin and poises genes for activation. Genome Res. 2011 May; 21(5):718-24. PMID: 21363969; PMCID: PMC3083088.
      Citations: 62     Fields:    Translation:AnimalsCells
    40. Daines B, Wang H, Wang L, Li Y, Han Y, Emmert D, Gelbart W, Wang X, Li W, Gibbs R, Chen R. The Drosophila melanogaster transcriptome by paired-end RNA sequencing. Genome Res. 2011 Feb; 21(2):315-24. PMID: 21177959; PMCID: PMC3032934.
      Citations: 78     Fields:    Translation:AnimalsCells
    41. Wiszniewski W, Lewis RA, Stockton DW, Peng J, Mardon G, Chen R, Lupski JR. Potential involvement of more than one locus in trait manifestation for individuals with Leber congenital amaurosis. Hum Genet. 2011 Mar; 129(3):319-27. PMID: 21153841; PMCID: PMC3625363.
      Citations: 13     Fields:    Translation:Humans
    42. Kim BJ, Li Y, Zhang J, Xi Y, Li Y, Yang T, Jung SY, Pan X, Chen R, Li W, Wang Y, Qin J. Genome-wide reinforcement of cohesin binding at pre-existing cohesin sites in response to ionizing radiation in human cells. J Biol Chem. 2010 Jul 23; 285(30):22784-92. PMID: 20501661; PMCID: PMC2906269.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    43. Wang H, Chattopadhyay A, Li Z, Daines B, Li Y, Gao C, Gibbs R, Zhang K, Chen R. Rapid identification of heterozygous mutations in Drosophila melanogaster using genomic capture sequencing. Genome Res. 2010 Jul; 20(7):981-8. PMID: 20472684; PMCID: PMC2892099.
      Citations: 16     Fields:    Translation:AnimalsCells
    44. Parikh A, Miranda ER, Katoh-Kurasawa M, Fuller D, Rot G, Zagar L, Curk T, Sucgang R, Chen R, Zupan B, Loomis WF, Kuspa A, Shaulsky G. Conserved developmental transcriptomes in evolutionarily divergent species. Genome Biol. 2010; 11(3):R35. PMID: 20236529; PMCID: PMC2864575.
      Citations: 110     Fields:    Translation:AnimalsCells
    45. Daines B, Wang H, Li Y, Han Y, Gibbs R, Chen R. High-throughput multiplex sequencing to discover copy number variants in Drosophila. Genetics. 2009 Aug; 182(4):935-41. PMID: 19528327; PMCID: PMC2728881.
      Citations: 14     Fields:    Translation:Animals
    46. Wang H, den Hollander AI, Moayedi Y, Abulimiti A, Li Y, Collin RW, Hoyng CB, Lopez I, Abboud EB, Al-Rajhi AA, Bray M, Lewis RA, Lupski JR, Mardon G, Koenekoop RK, Chen R. Mutations in SPATA7 cause Leber congenital amaurosis and juvenile retinitis pigmentosa. Am J Hum Genet. 2009 Mar; 84(3):380-7. PMID: 19268277; PMCID: PMC2668010.
      Citations: 63     Fields:    Translation:HumansAnimals
    47. Srivatsan A, Han Y, Peng J, Tehranchi AK, Gibbs R, Wang JD, Chen R. High-precision, whole-genome sequencing of laboratory strains facilitates genetic studies. PLoS Genet. 2008 Aug 01; 4(8):e1000139. PMID: 18670626; PMCID: PMC2474695.
      Citations: 127     Fields:    Translation:Cells
    48. Rhesus Macaque Genome Sequencing and Analysis Consortium, Gibbs RA, Rogers J, Katze MG, Bumgarner R, Weinstock GM, Mardis ER, Remington KA, Strausberg RL, Venter JC, Wilson RK, Batzer MA, Bustamante CD, Eichler EE, Hahn MW, Hardison RC, Makova KD, Miller W, Milosavljevic A, Palermo RE, Siepel A, Sikela JM, Attaway T, Bell S, Bernard KE, Buhay CJ, Chandrabose MN, Dao M, Davis C, Delehaunty KD, Ding Y, Dinh HH, Dugan-Rocha S, Fulton LA, Gabisi RA, Garner TT, Godfrey J, Hawes AC, Hernandez J, Hines S, Holder M, Hume J, Jhangiani SN, Joshi V, Khan ZM, Kirkness EF, Cree A, Fowler RG, Lee S, Lewis LR, Li Z, Liu YS, Moore SM, Muzny D, Nazareth LV, Ngo DN, Okwuonu GO, Pai G, Parker D, Paul HA, Pfannkoch C, Pohl CS, Rogers YH, Ruiz SJ, Sabo A, Santibanez J, Schneider BW, Smith SM, Sodergren E, Svatek AF, Utterback TR, Vattathil S, Warren W, White CS, Chinwalla AT, Feng Y, Halpern AL, Hillier LW, Huang X, Minx P, Nelson JO, Pepin KH, Qin X, Sutton GG, Venter E, Walenz BP, Wallis JW, Worley KC, Yang SP, Jones SM, Marra MA, Rocchi M, Schein JE, Baertsch R, Clarke L, Glasscock J, Harris RA, Havlak P, Jackson AR, Jiang H, Liu Y, Messina DN, Shen Y, Song HX, Wylie T, Zhang L, Birney E, Han K, Konkel MK, Lee J, Smit AF, Ullmer B, Wang H, Xing J, Burhans R, Cheng Z, Karro JE, Ma J, Raney B, She X, Cox MJ, Demuth JP, Dumas LJ, Han SG, Hopkins J, Karimpour-Fard A, Kim YH, Pollack JR, Vinar T, Addo-Quaye C, Degenhardt J, Denby A, Hubisz MJ, Indap A, Kosiol C, Lahn BT, Lawson HA, Marklein A, Nielsen R, Vallender EJ, Clark AG, Ferguson B, Hernandez RD, Hirani K, Kehrer-Sawatzki H, Kolb J, Patil S, Pu LL, Ren Y, Smith DG, Wheeler DA, Schenck I, Ball EV, Chen R, Cooper DN, Giardine B, Hsu F, Kent WJ, Lesk A, Nelson DL, O'brien WE, Stenson PD, Wallace JC, Ke H, Liu XM, Wang P, Xiang AP, Yang F, Barber GP, Haussler D, Karolchik D, Kern AD, Kuhn RM, Smith KE, Zwieg AS, Cs?r?s M, Pr?fer K. Evolutionary and biomedical insights from the rhesus macaque genome. Science. 2007 Apr 13; 316(5822):222-34. PMID: 17431167.
      Citations: 677     Fields:    Translation:HumansAnimals
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      Citations: 18     Fields:    Translation:HumansAnimalsCells
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    52. Chen R, Mardon G. Keeping an eye on the fly genome. Dev Biol. 2005 Jun 15; 282(2):285-93. PMID: 15893305.
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    53. Pappu KS, Ostrin EJ, Middlebrooks BW, Sili BT, Chen R, Atkins MR, Gibbs R, Mardon G. Dual regulation and redundant function of two eye-specific enhancers of the Drosophila retinal determination gene dachshund. Development. 2005 Jun; 132(12):2895-905. PMID: 15930118.
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      Citations: 282     Fields:    Translation:AnimalsCells
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      Citations: 65     Fields:    Translation:AnimalsCells
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      Citations: 881     Fields:    Translation:HumansAnimalsCells
    58. Chen R, Sodergren E, Weinstock GM, Gibbs RA. Dynamic building of a BAC clone tiling path for the Rat Genome Sequencing Project. Genome Res. 2004 Apr; 14(4):679-84. PMID: 15060010; PMCID: PMC383313.
      Citations: 6     Fields:    Translation:AnimalsCells
    59. Pappu KS, Chen R, Middlebrooks BW, Woo C, Heberlein U, Mardon G. Mechanism of hedgehog signaling during Drosophila eye development. Development. 2003 Jul; 130(13):3053-62. PMID: 12756186.
      Citations: 36     Fields:    Translation:AnimalsCells
    60. Chen R, Bouck JB, Weinstock GM, Gibbs RA. Comparing vertebrate whole-genome shotgun reads to the human genome. Genome Res. 2001 Nov; 11(11):1807-16. PMID: 11691844; PMCID: PMC311156.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    61. Cai WW, Chen R, Gibbs RA, Bradley A. A clone-array pooled shotgun strategy for sequencing large genomes. Genome Res. 2001 Oct; 11(10):1619-23. PMID: 11591638.
      Citations: 20     Fields:    Translation:HumansAnimals
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