"SUMO-1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 1.5-kDa small ubiquitin-related modifier protein that can covalently bind via an isopeptide link to a number of cellular proteins. It may play a role in intracellular protein transport and a number of other cellular processes.
| Descriptor ID |
D025842
|
| MeSH Number(s) |
D12.776.947.249.500
|
| Concept/Terms |
SUMO-1 Protein- SUMO-1 Protein
- SUMO 1 Protein
- Gap-modifying Protein 1
- Gap modifying Protein 1
- PIC 1 Protein
- PIC1 Protein
- Ubiquitin-like 1 Gene Product
- Ubiquitin like 1 Gene Product
- Protein GMP1
- GMP1, Protein
- Sentrin
- Sentrin 1
- SMT3C Protein
- SUMO Protein
- UBL1 Protein
- PML-Interacting Clone Protein
- PML Interacting Clone Protein
|
Below are MeSH descriptors whose meaning is more general than "SUMO-1 Protein".
Below are MeSH descriptors whose meaning is more specific than "SUMO-1 Protein".
This graph shows the total number of publications written about "SUMO-1 Protein" by people in this website by year, and whether "SUMO-1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 2 | 0 | 2 |
| 2005 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "SUMO-1 Protein" by people in Profiles.
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Constitutively active androgen receptor supports the metastatic phenotype of endocrine-resistant hormone receptor-positive breast cancer. Cell Commun Signal. 2020 09 18; 18(1):154.
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Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function. J Allergy Clin Immunol. 2018 05; 141(5):1844-1853.e2.
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SUMO Modification Reverses Inhibitory Effects of Smad Nuclear Interacting Protein-1 in TGF-? Responses. J Biol Chem. 2016 Nov 18; 291(47):24418-24430.
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PIAS1 is a GATA4 SUMO ligase that regulates GATA4-dependent intestinal promoters independent of SUMO ligase activity and GATA4 sumoylation. PLoS One. 2012; 7(4):e35717.
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Defective sumoylation pathway directs congenital heart disease. Birth Defects Res A Clin Mol Teratol. 2011 Jun; 91(6):468-76.
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Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1alpha: regulation by SUMOylation and oxidation. Hum Mol Genet. 2008 Nov 01; 17(21):3357-67.
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Transforming growth factor-beta-independent regulation of myogenesis by SnoN sumoylation. J Biol Chem. 2007 Mar 02; 282(9):6517-24.
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A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation. Biochem Biophys Res Commun. 2005 Nov 18; 337(2):517-20.
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Repression of Smad4 transcriptional activity by SUMO modification. Biochem J. 2004 Apr 01; 379(Pt 1):23-9.
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SUMO-1/Ubc9 promotes nuclear accumulation and metabolic stability of tumor suppressor Smad4. J Biol Chem. 2003 Aug 15; 278(33):31043-8.