"Nicotinic Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
| Descriptor ID |
D018733
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| MeSH Number(s) |
D27.505.519.625.120.200.700 D27.505.696.577.120.200.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Nicotinic Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Nicotinic Antagonists".
This graph shows the total number of publications written about "Nicotinic Antagonists" by people in this website by year, and whether "Nicotinic Antagonists" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nicotinic Antagonists" by people in Profiles.
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Neuronal Nicotinic Acetylcholine Receptor Modulators Reduce Sugar Intake. PLoS One. 2016; 11(3):e0150270.
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Novel role of Egr-1 in nicotine-related neointimal formation. Cardiovasc Res. 2010 Nov 01; 88(2):296-303.
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Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice. J Neurosci. 2009 Mar 11; 29(10):3014-8.
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Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit. Neuropharmacology. 2007 Dec; 53(7):863-9.
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Potentiation of glutamatergic synaptic input to supraoptic neurons by presynaptic nicotinic receptors. Am J Physiol Regul Integr Comp Physiol. 2001 Oct; 281(4):R1105-13.
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Spinal endogenous acetylcholine contributes to the analgesic effect of systemic morphine in rats. Anesthesiology. 2001 Aug; 95(2):525-30.
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Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron. 2001 Jul 19; 31(1):131-41.
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Nicotinic modulation of mesoprefrontal dopamine neurons: pharmacologic and neuroanatomic characterization. J Pharmacol Exp Ther. 2000 Oct; 295(1):58-66.
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Inhibition and disinhibition of pyramidal neurons by activation of nicotinic receptors on hippocampal interneurons. J Neurophysiol. 2000 May; 83(5):2682-90.
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Role of spinal muscarinic and nicotinic receptors in clonidine-induced nitric oxide release in a rat model of neuropathic pain. Brain Res. 2000 Apr 10; 861(2):390-8.