Mitogen-Activated Protein Kinase 14
"Mitogen-Activated Protein Kinase 14" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 38-kDa mitogen-activated protein kinase that is abundantly expressed in a broad variety of cell types. It is involved in the regulation of cellular stress responses as well as the control of proliferation and survival of many cell types. The kinase activity of the enzyme is inhibited by the pyridinyl-imidazole compound SB 203580.
| Descriptor ID |
D048308
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.567.843.937 D12.644.360.450.835.800 D12.776.476.450.835.937
|
| Concept/Terms |
Mitogen-Activated Protein Kinase 14- Mitogen-Activated Protein Kinase 14
- Mitogen Activated Protein Kinase 14
- CSAID-Binding Protein
- CSAID Binding Protein
- Kinase CSBP
- CSBP, Kinase
- p38alpha MAP Kinase
- MAP Kinase, p38alpha
- p38alphaMAPK
- Cytokine Suppressive Anti-inflammatory Drug Binding Protein
- Cytokine Suppressive Anti inflammatory Drug Binding Protein
- Mxi2 Protein
- MAX-Interacting Protein 2
- MAX Interacting Protein 2
- p38alpha Mitogen-Activated Protein Kinase
- p38alpha Mitogen Activated Protein Kinase
- MAPK14
- Stress-activated protein kinase 2a
- Stress activated protein kinase 2a
- SAPK2a
- MAPK14 Mitogen-Activated Protein Kinase
- MAPK14 Mitogen Activated Protein Kinase
|
Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase 14".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase 14".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase 14" by people in this website by year, and whether "Mitogen-Activated Protein Kinase 14" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinase 14" by people in Profiles.
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Role of p38 MAP kinase in cancer stem cells and metastasis. Oncogene. 2022 06; 41(23):3177-3185.
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mTOR Activation Initiates Renal Cell Carcinoma Development by Coordinating ERK and p38MAPK. Cancer Res. 2021 06 15; 81(12):3174-3186.
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Bone morphogenetic protein 7 promotes resistance to immunotherapy. Nat Commun. 2020 09 24; 11(1):4840.
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p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells. J Biol Chem. 2017 09 15; 292(37):15266-15276.
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Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38a activation. Nat Commun. 2017 01 09; 8:13956.
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Loss of Functionally Redundant p38 Isoforms in T Cells Enhances Regulatory T Cell Induction. J Biol Chem. 2017 02 03; 292(5):1762-1772.
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Dicer Elicits Paclitaxel Chemosensitization and Suppresses Cancer Stemness in Breast Cancer by Repressing AXL. Cancer Res. 2016 07 01; 76(13):3916-28.
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P38a MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism. Hum Mol Genet. 2014 Oct 15; 23(20):5452-63.
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Randomized, dose-escalation study of the p38a MAPK inhibitor SCIO-469 in patients with myelodysplastic syndrome. Leukemia. 2013 Apr; 27(4):977-80.
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Cellular signals underlying ?-adrenergic receptor mediated salivary gland enlargement. Differentiation. 2012 Jan; 83(1):68-76.