15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
"15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)
| Descriptor ID |
D019796
|
| MeSH Number(s) |
D01.248.497.158.685.750.744.650.500.500 D01.339.431.374.744.650.500.500 D01.650.550.750.700.650.500.500 D02.389.338.638.650.500.500 D10.251.355.255.550.025.650.500.500 D23.469.050.175.725.025.650.500.500 D23.469.700.630.500
|
| Concept/Terms |
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
- 9,11-Dideoxy-11 alpha,9-alpha-epoxymethano-PGF2 alpha
- 9,11-epoxymethano-PGH2
- 9,11 epoxymethano PGH2
- 11 alpha,9 alpha-Epoxymethano PGH2
- 11 alpha,9 alpha Epoxymethano PGH2
- (15S)hydroxy-9alpha,11alpha-(epoxymethano)prosta-5,13-dienoic acid
- (15S)-Hydroxy-11 alpha, 9 alpha-(epoxymethano)prosta-5Z, 13E-dienoic Acid
- 9,11-Dideoxy-11 alpha,9 alpha-epoxymethanoprostaglandin F2 alpha
U-44619- U-44619
- U 44619
- U46619
- U44619
- U-46619
- U 46619
|
Below are MeSH descriptors whose meaning is more general than "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid".
- Chemicals and Drugs [D]
- Inorganic Chemicals [D01]
- Electrolytes [D01.248]
- Ions [D01.248.497]
- Anions [D01.248.497.158]
- Oxides [D01.248.497.158.685]
- Peroxides [D01.248.497.158.685.750]
- Prostaglandin Endoperoxides [D01.248.497.158.685.750.744]
- Prostaglandins H [D01.248.497.158.685.750.744.650]
- Prostaglandin H2 [D01.248.497.158.685.750.744.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D01.248.497.158.685.750.744.650.500.500]
- Free Radicals [D01.339]
- Reactive Oxygen Species [D01.339.431]
- Peroxides [D01.339.431.374]
- Prostaglandin Endoperoxides [D01.339.431.374.744]
- Prostaglandins H [D01.339.431.374.744.650]
- Prostaglandin H2 [D01.339.431.374.744.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D01.339.431.374.744.650.500.500]
- Oxygen Compounds [D01.650]
- Oxides [D01.650.550]
- Peroxides [D01.650.550.750]
- Prostaglandin Endoperoxides [D01.650.550.750.700]
- Prostaglandins H [D01.650.550.750.700.650]
- Prostaglandin H2 [D01.650.550.750.700.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D01.650.550.750.700.650.500.500]
- Organic Chemicals [D02]
- Free Radicals [D02.389]
- Peroxides [D02.389.338]
- Prostaglandin Endoperoxides [D02.389.338.638]
- Prostaglandins H [D02.389.338.638.650]
- Prostaglandin H2 [D02.389.338.638.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D02.389.338.638.650.500.500]
- Lipids [D10]
- Fatty Acids [D10.251]
- Fatty Acids, Unsaturated [D10.251.355]
- Eicosanoids [D10.251.355.255]
- Prostaglandins [D10.251.355.255.550]
- Prostaglandin Endoperoxides [D10.251.355.255.550.025]
- Prostaglandins H [D10.251.355.255.550.025.650]
- Prostaglandin H2 [D10.251.355.255.550.025.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D10.251.355.255.550.025.650.500.500]
- Biological Factors [D23]
- Inflammation Mediators [D23.469]
- Autacoids [D23.469.050]
- Eicosanoids [D23.469.050.175]
- Prostaglandins [D23.469.050.175.725]
- Prostaglandin Endoperoxides [D23.469.050.175.725.025]
- Prostaglandins H [D23.469.050.175.725.025.650]
- Prostaglandin H2 [D23.469.050.175.725.025.650.500]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D23.469.050.175.725.025.650.500.500]
- Prostaglandins, Synthetic [D23.469.700]
- Prostaglandin Endoperoxides, Synthetic [D23.469.700.630]
- 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid [D23.469.700.630.500]
Below are MeSH descriptors whose meaning is more specific than "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid".
This graph shows the total number of publications written about "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid" by people in this website by year, and whether "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid" by people in Profiles.
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Calcitonin Gene Related Peptide, Adrenomedullin, and Adrenomedullin 2 Function in Uterine Artery During Human Pregnancy. Endocrinology. 2022 01 01; 163(1).
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Twik-2-/- mouse demonstrates pulmonary vascular heterogeneity in intracellular pathways for vasocontractility. Physiol Rep. 2019 01; 7(1):e13950.
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Impaired Vasodilatory Responses of Omental Arteries to CGRP Family Peptides in Pregnancies Complicated by Fetal Growth Restriction. J Clin Endocrinol Metab. 2016 08; 101(8):2984-93.
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Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice. Hypertension. 2011 Oct; 58(4):672-8.
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Structural and functional analysis of the C-terminus of Galphaq in complex with the human thromboxane A2 receptor provides evidence of constitutive activity. Biochemistry. 2010 Aug 03; 49(30):6365-74.
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Noninvasive assessment of murine pulmonary arterial pressure: validation and application to models of pulmonary hypertension. Circ Cardiovasc Imaging. 2010 Mar; 3(2):157-63.
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Augmentation of U46619 induced human platelet aggregation by aspirin. Platelets. 2009 Mar; 20(2):111-9.
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Capsaicin blocks HIV protease inhibitor ritonavir-induced vascular dysfunction in porcine pulmonary arteries. Med Sci Monit. 2009 Jan; 15(1):BR1-5.
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Characterization of the substrate mimic bound to engineered prostacyclin synthase in solution using high-resolution NMR spectroscopy and mutagenesis: implication of the molecular mechanism in biosynthesis of prostacyclin. Biochemistry. 2008 Jan 15; 47(2):680-8.
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Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol-induced acute renal failure. J Pharmacol Exp Ther. 2007 Aug; 322(2):461-8.